{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:29:02Z","timestamp":1787754542481,"version":"build-2784847793"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"published-print":{"date-parts":[[2015,9,23]]},"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>Although recombinant human bone morphogenetic protein-2 (rhBMP-2) is approved for treatment of open tibial fractures and anterior lumbar interbody fusion, off-label use has been associated with complications such as local inflammation, osteolysis, and dysphagia. This case report describes a patient treated with rhBMP-2 for an atrophic delayed union of a clavicular fracture who subsequently developed a profound motor and sensory brachial plexopathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Use of rhBMP-2 near peripheral nerves may cause neuropathy. This should be considered prior to its use in surgical sites with peripheral nerves in proximity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.n.00187","type":"journal-article","created":{"date-parts":[[2015,9,23]],"date-time":"2015-09-23T23:04:21Z","timestamp":1443049461000},"page":"e81","source":"Crossref","is-referenced-by-count":7,"title":["Brachial Plexopathy Following Use of Recombinant Human BMP-2 for Treatment of Atrophic Delayed Union of the Clavicle"],"prefix":"10.2106","volume":"5","author":[{"given":"John R.","family":"Matthews","sequence":"first","affiliation":[{"name":"College of Medicine \u2013 Tucson, University of Arizona, 1501 North Campbell Avenue, Tucson, AZ 85724"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Margolis","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arizona, 1609 North Warren Avenue, Room 108, Tucson, AZ 85719. E-mail address for L.M. Truchan:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arizona, 1609 North Warren Avenue, Room 108, Tucson, AZ 85719. E-mail address for L.M. Truchan:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Truchan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arizona, 1609 North Warren Avenue, Room 108, Tucson, AZ 85719. E-mail address for L.M. Truchan:"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"3","key":"bib1-20231015","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1302\/0301-620X.80B3.0800476","article-title":"Fractures of the clavicle in the adult. 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