{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T13:00:38Z","timestamp":1788786038041,"version":"build-2803163510"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8,4]]},"DOI":"10.2106\/jbjs.i.01140","type":"journal-article","created":{"date-parts":[[2010,8,4]],"date-time":"2010-08-04T18:49:13Z","timestamp":1280947753000},"page":"1876-1883","source":"Crossref","is-referenced-by-count":68,"title":["Musculoskeletal Findings of Loeys-Dietz Syndrome"],"prefix":"10.2106","volume":"92","author":[{"given":"Gurkan","family":"Erkula","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Sponseller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura C.","family":"Paulsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretchen L.","family":"Oswald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart L.","family":"Loeys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry C.","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20210131","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1056\/NEJMoa055695","article-title":"Aneurysm syndromes caused by mutations in the TGF-beta receptor","volume":"355","year":"2006","journal-title":"N Engl J Med."},{"key":"bib2-20210131","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ng1511","article-title":"A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2","volume":"37","year":"2005","journal-title":"Nat Genet."},{"key":"bib3-20210131","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jtcvs.2007.03.004","article-title":"Rapid aneurysmal degeneration of a Stanford type B aortic dissection in a patient with Loeys-Dietz syndrome","volume":"134","year":"2007","journal-title":"J Thorac Cardiovasc Surg."},{"key":"bib4-20210131","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/ncpcardio0797","article-title":"Severe aortic and arterial aneurysms associated with a TGFBR2 mutation","volume":"4","year":"2007","journal-title":"Nat Clin Pract Cardiovasc Med."},{"key":"bib5-20210131","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1002\/humu.20354","article-title":"TGFBR1 and TGFBR2 mutations in patients with features of Marfan syndrome and Loeys-Dietz syndrome","volume":"27","year":"2006","journal-title":"Hum Mutat."},{"key":"bib6-20210131","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1002\/pd.1565","article-title":"Fetal aortic root dilation: a prenatal feature of the Loeys-Dietz syndrome","volume":"26","year":"2006","journal-title":"Prenat Diagn."},{"key":"bib7-20210131","doi-asserted-by":"crossref","first-page":"e1199","DOI":"10.1542\/peds.2006-2886","article-title":"Importance of the clinical recognition of Loeys-Dietz syndrome in the neonatal period","volume":"119","year":"2007","journal-title":"Pediatrics."},{"key":"bib8-20210131","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1177\/000992286800700716","article-title":"The \"thumb sign\" in children","volume":"7","year":"1968","journal-title":"Clin Pediatr (Phila)."},{"key":"bib9-20210131","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/archinte.1970.00310080082011","article-title":"The wrist sign. A useful physical finding in the Marfan syndrome","volume":"126","year":"1970","journal-title":"Arch Intern Med."},{"key":"bib10-20210131","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/(SICI)1096-8628(19960424)62:4<417::AID-AJMG15>3.0.CO;2-R","article-title":"Revised diagnostic criteria for the Marfan syndrome","volume":"62","year":"1996","journal-title":"Am J Med Genet."},{"key":"bib11-20210131","first-page":"5","article-title":"Bony interorbital distance (BIOD), head size, and level of the cribriform plate relative to orbital height: I. Normal standards for age and sex","volume":"2","year":"1982","journal-title":"J Craniofac Genet Dev Biol."},{"key":"bib12-20210131","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2214\/ajr.137.1.83","article-title":"Estimating fetal age: effect of head shape on BPD","volume":"137","year":"1981","journal-title":"AJR Am J Roentgenol."},{"key":"bib13-20210131","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S1079-2104(05)80192-1","article-title":"Cephalometric profile evaluations in patients with cleft lip and palate","volume":"80","year":"1995","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004623-201008040-00009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:26:47Z","timestamp":1787750807000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004623-201008040-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,4]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.i.01140","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,4]]}}}