{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:36:02Z","timestamp":1787754962291,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Supplement_1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,3,16]]},"abstract":"\n BACKGROUND:<\/jats:title>\n There is a variety of treatment modalities for unicameral bone cysts, with variable outcomes reported in the literature. Although good initial outcomes have been reported, the success rate has often changed with longer-term follow-up. We introduce a novel, minimally invasive treatment method and compare its clinical outcomes with those of other methods of treatment of this lesion.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n From February 1994 to April 2008, forty patients with a unicameral bone cyst were treated with one of four techniques: serial percutaneous steroid and autogenous bone-marrow injection (Group 1, nine patients); open curettage and grafting with a calcium sulfate bone substitute either without instrumentation (Group 2, twelve patients) or with internal instrumentation (Group 3, seven patients); or minimally invasive curettage, ethanol cauterization, disruption of the cystic boundary, insertion of a synthetic calcium sulfate bone-graft substitute, and placement of a cannulated screw to provide drainage (Group 4, twelve patients). Success was defined as radiographic evidence of a healed cyst or of a healed cyst with some defect according to the modified Neer classification, and failure was defined as a persistent or recurrent cyst that needed additional treatment. Patients who sustained a fracture during treatment were also considered to have had a failure. The outcome parameters included the radiographically determined healing rate, the time to solid union, and the total number of procedures needed.<\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n The follow-up time ranged from eighteen to eighty-four months. Group-4 patients had the highest radiographically determined healing rate. Healing was seen in eleven of the twelve patients in that group compared with three of the nine in Group 1, eight of the twelve in Group 2, and six of the seven in Group 3. Group-4 patients also had the shortest mean time to union: 3.7 \u00b1 2.3 months compared with 23.4 \u00b1 14.9, 12.2 \u00b1 8.5, and 6.6 \u00b1 4.3 months in Groups 1, 2, and 3, respectively.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n This new minimally invasive method achieved a favorable outcome, with a higher radiographically determined healing rate and a shorter time to union. Thus, it can be considered an option for initial treatment of unicameral bone cysts.<\/jats:p>\n <\/jats:sec>\n \n LEVEL OF EVIDENCE:<\/jats:title>\n \n Therapeutic\n Level III<\/jats:underline>\n . See Instructions to Authors for a complete description of levels of evidence.\n <\/jats:p>\n <\/jats:sec>\n \n ORIGINAL ABSTRACT CITATION:<\/jats:title>\n \u201cTreatment of Unicameral Bone Cyst. A Comparative Study of Selected Techniques\u201d (2010;92:855-62).<\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.j.01123","type":"journal-article","created":{"date-parts":[[2011,3,16]],"date-time":"2011-03-16T13:49:14Z","timestamp":1300283354000},"page":"92-99","source":"Crossref","is-referenced-by-count":41,"title":["Treatment of Unicameral Bone Cyst"],"prefix":"10.2106","volume":"93","author":[{"given":"Hsien-Yang","family":"Hou","sequence":"first","affiliation":[{"name":"Division of Orthopaedics, Department of Surgery, Landseed Hospital, Number 77, Kwang-Tai Road, Ping-Jen, Tao-yuan, Taiwan 32449. E-mail address for H.-Y. Hou:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Orthopaedics, Department of Surgery, Far Eastern Memorial Hospital, Number 21, Section 2, Nan-Ya South Road, Pan-Chiao, Taipei, Taiwan 22060"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen-Ti","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, College of Medicine, National Taiwan University Hospital, Number 7, Chung-Shan South Road, Taipei, Taiwan 10002. E-mail address for R.-S. Yang:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun-Min","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Orthopaedics, Department of Surgery, Landseed Hospital, Number 77, Kwang-Tai Road, Ping-Jen, Tao-yuan, Taiwan 32449. E-mail address for H.-Y. Hou:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Hsin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, College of Medicine, National Taiwan University Hospital, Number 7, Chung-Shan South Road, Taipei, Taiwan 10002. E-mail address for R.-S. Yang:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Sen","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, College of Medicine, National Taiwan University Hospital, Number 7, Chung-Shan South Road, Taipei, Taiwan 10002. E-mail address for R.-S. Yang:"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20230714","first-page":"25","article-title":"Unicameral and aneurysmal bone cysts","volume":"204","year":"1986","journal-title":"Clin Orthop Relat Res."},{"key":"bib2-20230714","first-page":"204","article-title":"The natural history of unicameral bone cyst after steroid injection","volume":"166","year":"1982","journal-title":"Clin Orthop Relat Res."},{"key":"bib3-20230714","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01241398-198401000-00001","article-title":"Operative treatment versus steroid injection in the management of unicameral bone cysts","volume":"4","year":"1984","journal-title":"J Pediatr Orthop."},{"key":"bib4-20230714","first-page":"200","article-title":"The effects of methylprednisolone acetate in the treatment of bone cysts. Results of three years follow-up","volume":"61","year":"1979","journal-title":"J Bone Joint Surg Br."},{"key":"bib5-20230714","first-page":"287","article-title":"Packing with high-porosity hydroxyapatite cubes alone for the treatment of simple bone cyst","volume":"293","year":"1993","journal-title":"Clin Orthop Relat Res."},{"key":"bib6-20230714","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/01241398-199401000-00020","article-title":"Unicameral bone cyst of the calcaneus in children","volume":"14","year":"1994","journal-title":"J Pediatr Orthop."},{"key":"bib7-20230714","doi-asserted-by":"crossref","first-page":"636","DOI":"10.2106\/00004623-197658050-00010","article-title":"Solitary unicameral bone cyst: treatment with freeze-dried crushed cortical-bone allograft. A review of one hundred and forty-four cases","volume":"58","year":"1976","journal-title":"J Bone Joint Surg Am."},{"key":"bib8-20230714","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/BPB.0b013e32826d1ad6","article-title":"Continuous decompression of unicameral bone cyst with cannulated screws: a comparative study","volume":"16","year":"2007","journal-title":"J Pediatr Orthop B."},{"key":"bib9-20230714","first-page":"539","article-title":"[Continuous decompression. A new method in the treatment of juvenile bone cysts]","volume":"93","year":"1990","journal-title":"Unfallchirurg."},{"key":"bib10-20230714","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1302\/0301-620X.84B2.0840245","article-title":"Cannulation of simple bone cysts","volume":"84","year":"2002","journal-title":"J Bone Joint Surg Br."},{"key":"bib11-20230714","first-page":"147","article-title":"[The treatment of upper femoral unicameral bone cysts in children by Ender's nailing technique]","volume":"67","year":"1981","journal-title":"Rev Chir Orthop Reparatrice Appar Mot."},{"key":"bib12-20230714","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.2106\/00004623-200010000-00011","article-title":"Flexible intramedullary nailing for the treatment of unicameral bone cysts in long bones","volume":"82","year":"2000","journal-title":"J Bone Joint Surg Am."},{"key":"bib13-20230714","doi-asserted-by":"crossref","first-page":"873","DOI":"10.3928\/0147-7447-19880601-06","article-title":"Treatment of solitary bone cysts with intramedullary nailing","volume":"11","year":"1988","journal-title":"Orthopedics."},{"key":"bib14-20230714","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.orthres.2005.02.012","article-title":"Zoledronate induces apoptosis in cells from fibro-cellular membrane of unicameral bone cyst (UBC)","volume":"23","year":"2005","journal-title":"J Orthop Res."},{"key":"bib15-20230714","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1097\/01241398-199809000-00012","article-title":"Autogenic bone marrow injections as a treatment for simple bone cyst","volume":"18","year":"1998","journal-title":"J Pediatr Orthop."},{"key":"bib16-20230714","first-page":"186","article-title":"The clinical use of autologous marrow to improve osteogenic potential of bone grafts in pediatric orthopedics","volume":"9","year":"1989","journal-title":"J Pediatr Orthop."},{"key":"bib17-20230714","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1302\/0301-620X.78B6.0780934","article-title":"Simple bone cysts treated by percutaneous autologous marrow grafting. A preliminary report","volume":"78","year":"1996","journal-title":"J Bone Joint Surg Br."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004623-201103001-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:35:34Z","timestamp":1787751334000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004623-201103001-00010"}},"subtitle":["Surgical Technique"],"short-title":[],"issued":{"date-parts":[[2011,3,16]]},"references-count":17,"journal-issue":{"issue":"Supplement_1","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.j.01123","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,16]]}}}