{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:23:15Z","timestamp":1788258195935,"version":"build-2803163510"},"reference-count":81,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,5,2]]},"DOI":"10.2106\/jbjs.j.01743","type":"journal-article","created":{"date-parts":[[2012,4,19]],"date-time":"2012-04-19T17:41:36Z","timestamp":1334857296000},"page":"815-823","source":"Crossref","is-referenced-by-count":111,"title":["The Effect of Nonsteroidal Anti-Inflammatory Drug Administration on Acute Phase Fracture-Healing: A Review"],"prefix":"10.2106","volume":"94","author":[{"given":"Andrew P.","family":"Kurmis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy P.","family":"Kurmis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin X.","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tore","family":"Dal\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"bib1-20210131","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/ALN.0b013e318164938c","article-title":"Impact of analgesia on bone fracture healing","volume":"108","year":"2008","journal-title":"Anesthesiology."},{"key":"bib2-20210131","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1067\/mem.2003.275","article-title":"Emergency department analgesia for fracture pain","volume":"42","year":"2003","journal-title":"Ann Emerg Med."},{"key":"bib3-20210131","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S0022-3565(25)21156-9","article-title":"Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance","volume":"279","year":"1996","journal-title":"J Pharmacol Exp Ther."},{"key":"bib4-20210131","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3109\/17453679809117607","article-title":"Indomethacin for prevention of heterotopic ossification after hip arthroplasty. A randomized comparison between 4 and 8 days of treatment","volume":"69","year":"1998","journal-title":"Acta Orthop Scand."},{"key":"bib5-20210131","first-page":"2020","article-title":"Nonsteroidal anti-inflammatory drugs in orthopaedics","volume":"91","year":"2009","journal-title":"J Bone Joint Surg Am."},{"key":"bib6-20210131","first-page":"407","article-title":"NSAID use following skeletal trauma","volume":"53","year":"2003","journal-title":"Br J Gen Prac."},{"key":"bib7-20210131","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0736-0266(03)00003-2","article-title":"Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs","volume":"21","year":"2003","journal-title":"J Orthop Res."},{"key":"bib8-20210131","first-page":"569","article-title":"Nonsteroidal anti-inflammatory drugs (NSAIDs) in the perioperative phase in traumatology and orthopedics effects on bone healing","volume":"17","year":"2005","journal-title":"Oper Orthop Traumatol."},{"key":"bib9-20210131","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF02850267","article-title":"Effect of diclofenac sodium on union of tibial fractures in rats","volume":"19","year":"2002","journal-title":"Adv Ther."},{"key":"bib10-20210131","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.csm.2005.08.004","article-title":"Pharmacologic agents in fracture healing","volume":"25","year":"2006","journal-title":"Clin Sports Med."},{"key":"bib11-20210131","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1080\/17453670710014365","article-title":"Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial","volume":"78","year":"2007","journal-title":"Acta Orthop."},{"key":"bib12-20210131","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1592\/phco.2005.25.11.1566","article-title":"Effects of perioperative antiinflammatory and immunomodulating therapy on surgical wound healing","volume":"25","year":"2005","journal-title":"Pharmacotherapy."},{"key":"bib13-20210131","doi-asserted-by":"crossref","first-page":"139","DOI":"10.5435\/00124635-200405000-00001","article-title":"Effects of nonsteroidal anti-inflammatory drugs on bone formation and soft-tissue healing","volume":"12","year":"2004","journal-title":"J Am Acad Orthop Surg."},{"key":"bib14-20210131","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1742-7843.2007.00149.x","article-title":"Non-steroidal anti-inflammatory drugs, cyclooxygenase-2 and the bone healing process","volume":"102","year":"2008","journal-title":"Basic Clin Pharmacol Toxicol."},{"key":"bib15-20210131","doi-asserted-by":"crossref","first-page":"116","DOI":"10.2106\/00004623-200401000-00017","article-title":"Effect of COX-2-specific inhibition on fracture-healing in the rat femur","volume":"86","year":"2004","journal-title":"J Bone Joint Surg Am."},{"key":"bib16-20210131","doi-asserted-by":"crossref","first-page":"588","DOI":"10.3109\/17453677608988744","article-title":"Effect of indomethacin on fracture healing in rats","volume":"47","year":"1976","journal-title":"Acta Orthop Scand."},{"key":"bib17-20210131","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF00415452","article-title":"Indomethacin-induced delayed fracture healing","volume":"85","year":"1976","journal-title":"Arch Orthop Unfallchir."},{"key":"bib19-20210131","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/newbio231232a0","article-title":"Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs","volume":"231","year":"1971","journal-title":"Nat New Biol."},{"key":"bib20-20210131","first-page":"5","article-title":"Cox-2: Where are we in 2003? The role of cyclooxygenase-2 in bone repair","volume":"5","year":"2003","journal-title":"Arthritis Res Ther."},{"key":"bib21-20210131","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1517\/14740338.3.2.131","article-title":"COX inhibitors and their effects on bone healing","volume":"3","year":"2004","journal-title":"Expert Opin Drug Saf."},{"key":"bib22-20210131","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1136\/emj.2005.028647","article-title":"Best evidence topic report. Do non-steroidal anti-inflammatory drugs cause a delay in fracture healing?","volume":"22","year":"2005","journal-title":"Emerg Med J."},{"key":"bib23-20210131","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00402-007-0288-9","article-title":"The non-steroidal anti-inflammatory drug diclofenac reduces appearance of osteoblasts in bone defect healing in rats","volume":"127","year":"2007","journal-title":"Arch Orthop Trauma Surg."},{"key":"bib24-20210131","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0736-0266(03)00003-2","article-title":"Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs","volume":"21","year":"2003","journal-title":"J Orthop Res."},{"key":"bib25-20210131","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1097\/01.bot.0000184144.98071.5d","article-title":"A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats","volume":"19","year":"2005","journal-title":"J Orthop Trauma."},{"key":"bib26-20210131","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.injury.2005.12.018","article-title":"Effect of COX-2 inhibitors and non-steroidal anti-inflammatory drugs on a mouse fracture model","volume":"37","year":"2006","journal-title":"Injury."},{"key":"bib27-20210131","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jbspin.2004.02.003","article-title":"COX-3: fact or fancy?","volume":"71","year":"2004","journal-title":"Joint Bone Spine."},{"issue":"Suppl. 3A","key":"bib28-20210131","first-page":"43S","article-title":"Potential impact of selective cyclooxygenase-2 inhibitors on bone metabolism in health and disease","volume":"110","year":"2001","journal-title":"Am J Med."},{"key":"bib29-20210131","first-page":"290","article-title":"Effects of cyclooxygenase inhibitors on bone and cartilage metabolism\u2014a review","volume":"16","year":"2007","journal-title":"Niger J Med."},{"key":"bib30-20210131","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1177\/014107680609900315","article-title":"Risk of cardiovascular events and celecoxib: a systematic review and meta-analysis","volume":"99","year":"2006","journal-title":"J R Soc Med."},{"key":"bib31-20210131","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/j.gastro.2004.04.003","article-title":"The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice","volume":"127","year":"2004","journal-title":"Gastroenterology."},{"key":"bib32-20210131","doi-asserted-by":"crossref","first-page":"452","DOI":"10.12968\/hmed.2007.68.8.24506","article-title":"Should non-steroidal anti-inflammatory drugs be given to orthopaedic patients with fractures?","volume":"68","year":"2007","journal-title":"Br J Hosp Med (Lond)."},{"key":"bib33-20210131","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1359\/jbmr.2002.17.6.963","article-title":"Cyclo-oxygenase 2 function is essential for bone fracture healing","volume":"17","year":"2002","journal-title":"J Bone Miner Res."},{"key":"bib34-20210131","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1172\/JCI0215681","article-title":"Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair","volume":"109","year":"2002","journal-title":"J Clin Invest."},{"key":"bib35-20210131","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1524-475X.2007.00243.x","article-title":"Cbfa1\/Runx2-deficiency delays bone wound healing and locally delivered Cbfa1\/Runx2 promotes bone repair in animal models","volume":"15","year":"2007","journal-title":"Wound Repair Regen."},{"key":"bib36-20210131","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1359\/jbmr.081248","article-title":"Positive regulation of adult bone formation by osteoblast-specific transcription factor osterix","volume":"24","year":"2009","journal-title":"J Bone Miner Res."},{"key":"bib37-20210131","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1056\/NEJM200011233432103","article-title":"Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group","volume":"343","year":"2000","journal-title":"N Engl J Med."},{"key":"bib38-20210131","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1056\/NEJMoa050493","article-title":"Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial","volume":"352","year":"2005","journal-title":"N Engl J Med."},{"key":"bib39-20210131","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1093\/ajhp\/61.21.2234","article-title":"MI risk prompts rofecoxib withdrawal","volume":"61","year":"2004","journal-title":"Am J Health Syst Pharm."},{"key":"bib40-20210131","first-page":"3","article-title":"Effects of diclofenac on periosteal callus maturation in osteotomy healing in an animal model","volume":"127","year":"2007","journal-title":"Arch Orthop Trauma Surg."},{"key":"bib41-20210131","first-page":"411","article-title":"Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib","volume":"92","year":"2003","journal-title":"Am J Cardiol."},{"key":"bib42-20210131","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.injury.2007.10.035","article-title":"Pharmacological agents and impairment of fracture healing: what is the evidence?","volume":"39","year":"2008","journal-title":"Injury."},{"key":"bib43-20210131","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/jor.1100090310","article-title":"The influence of ibuprofen on fracture repair: biomechanical, biochemical, histologic, and histomorphometric parameters in rats","volume":"9","year":"1991","journal-title":"J Orthop Res."},{"key":"bib44-20210131","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/jor.20461","article-title":"Low-intensity pulsed ultrasound and nonsteroidal anti-inflammatory drugs have opposing effects during stress fracture repair","volume":"25","year":"2007","journal-title":"J Orthop Res."},{"key":"bib45-20210131","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.phrs.2003.12.017","article-title":"Is there an inhibitory effect of COX-2 inhibitors on bone healing?","volume":"50","year":"2004","journal-title":"Pharmacol Res."},{"key":"bib46-20210131","doi-asserted-by":"crossref","first-page":"500","DOI":"10.2106\/JBJS.F.00127","article-title":"Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing","volume":"89","year":"2007","journal-title":"J Bone Joint Surg Am."},{"key":"bib47-20210131","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1080\/17453670510041439","article-title":"Cyclooxygenase-2 inhibitor delays fracture healing in rats","volume":"76","year":"2005","journal-title":"Acta Orthop."},{"key":"bib48-20210131","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.ejphar.2007.06.030","article-title":"Inhibition of cyclooxygenase-2 down-regulates osteoclast and osteoblast differentiation and favours adipocyte formation in vitro","volume":"572","year":"2007","journal-title":"Eur J Pharmacol."},{"key":"bib49-20210131","first-page":"351","article-title":"Histological aspects of bone fracture healing","volume":"7","year":"2005","journal-title":"Ortop Traumatol Rehabil."},{"key":"bib50-20210131","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s00011-005-1367-4","article-title":"Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing","volume":"54","year":"2005","journal-title":"Inflamm Res."},{"key":"bib51-20210131","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1097\/00005131-200211000-00006","article-title":"Bone formation following intramedullary femoral reaming is decreased by indomethacin and antibodies to insulin-like growth factors","volume":"16","year":"2002","journal-title":"J Orthop Trauma."},{"key":"bib52-20210131","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1365-2362.1979.tb00893.x","article-title":"Inhibition of fracture healing by indomethacin in rats","volume":"9","year":"1979","journal-title":"Eur J Clin Invest."},{"key":"bib53-20210131","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3109\/17453679809117606","article-title":"Heterotopic ossification","volume":"69","year":"1998","journal-title":"Acta Orthop Scand."},{"key":"bib54-20210131","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1023\/A:1024830213832","article-title":"Prevention of heterotopic ossification after total hip replacement with NSAIDs","volume":"25","year":"2003","journal-title":"Pharm World Sci."},{"key":"bib55-20210131","doi-asserted-by":"crossref","first-page":"419","DOI":"10.2165\/11533350-000000000-00000","article-title":"Oral cyclo-oxygenase 2 inhibitors versus other oral analgesics for acute soft tissue injury: systematic review and meta-analysis","volume":"30","year":"2010","journal-title":"Clin Drug Investig."},{"issue":"Suppl. 3","key":"bib56-20210131","first-page":"140","article-title":"Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis?","volume":"88","year":"2006","journal-title":"J Bone Joint Surg Am."},{"key":"bib57-20210131","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1080\/17453670710015373","article-title":"Negative effect of parecoxib on bone mineral during fracture healing in rats","volume":"79","year":"2008","journal-title":"Acta Orthop."},{"key":"bib58-20210131","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3109\/17453679209154794","article-title":"Fracture healing in rats inhibited by locally administered indomethacin","volume":"63","year":"1992","journal-title":"Acta Orthop Scand."},{"key":"bib59-20210131","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s00402-003-0537-5","article-title":"Influence of diclofenac (group of nonsteroidal anti-inflammatory drugs) on fracture healing","volume":"123","year":"2003","journal-title":"Arch Orthop Trauma Surg."},{"key":"bib60-20210131","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/S0736-0266(02)00079-7","article-title":"COX-2 selective NSAID decreases bone ingrowth in vivo","volume":"20","year":"2002","journal-title":"J Orthop Res."},{"key":"bib61-20210131","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1177\/039463200301600303","article-title":"COX-2 selective inhibitors and bone","volume":"16","year":"2003","journal-title":"Int J Immunopathol Pharmacol."},{"key":"bib62-20210131","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/00005131-199505000-00006","article-title":"Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats","volume":"9","year":"1995","journal-title":"J Orthop Trauma."},{"key":"bib63-20210131","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1136\/bjsm.2004.012492","article-title":"Do non-steroidal anti-inflammatory drugs adversely affect stress fracture healing? A short review","volume":"39","year":"2005","journal-title":"Br J Sports Med."},{"key":"bib64-20210131","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s004020050310","article-title":"Effects of ketoralac tromethamine and indomethacin on primary and secondary bone healing. An experimental study in rats","volume":"118","year":"1998","journal-title":"Arch Orthop Trauma Surg."},{"issue":"6 Pt 1","key":"bib65-20210131","first-page":"621","article-title":"Indomethacin-induced inhibition of haversian remodelling in rabbits","volume":"50","year":"1979","journal-title":"Acta Orthop Scand."},{"key":"bib66-20210131","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0020-1383(02)00199-7","article-title":"Effect of tenoxicam on fracture healing in rat tibiae","volume":"34","year":"2003","journal-title":"Injury."},{"key":"bib67-20210131","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.biopha.2006.06.017","article-title":"Selective cyclooxygenase inhibition: its role in pain and anaesthesia","volume":"60","year":"2006","journal-title":"Biomed Pharmacother."},{"key":"bib68-20210131","first-page":"79","article-title":"Effects of a cyclooxygenase-2 inhibitor (rofecoxib) on bone healing","volume":"35","year":"2006","journal-title":"Am J Orthop (Belle Mead NJ)."},{"key":"bib69-20210131","first-page":"279","article-title":"Temporal effects of a COX-2-selective NSAID on bone in growth","volume":"72","year":"2005","journal-title":"J Biomed Mater Res A."},{"key":"bib70-20210131","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1590\/S1806-83242005000400014","article-title":"Selective COX-2 inhibitor reduces bone healing in bone defects","volume":"19","year":"2005","journal-title":"Braz Oral Res."},{"key":"bib71-20210131","first-page":"1253","article-title":"The effects of the short-term administration of low therapeutic doses of anti-COX-2 agents on the healing of fractures. An experimental study in rabbits","volume":"89","year":"2007","journal-title":"J Bone Joint Surg Br."},{"key":"bib72-20210131","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.2106\/00004623-200210000-00004","article-title":"The effect of cyclooxygenase-2 inhibitors on spinal fusion","volume":"84","year":"2002","journal-title":"J Bone Joint Surg Am."},{"key":"bib73-20210131","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2114\/jpa.21.235","article-title":"Cyclooxygenase-2 inhibitor inhibits the fracture healing","volume":"21","year":"2002","journal-title":"J Physiol Anthropol Appl Human Sci."},{"key":"bib74-20210131","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1302\/0301-620X.82B5.0820655","article-title":"Nonunion of the femoral diaphysis. The influence of reaming and non-steroidal anti-inflammatory drugs","volume":"82","year":"2000","journal-title":"J Bone Joint Surg Br."},{"key":"bib75-20210131","first-page":"1553","article-title":"Inhibition of fracture healing","volume":"89","year":"2007","journal-title":"J Bone Joint Surg Br."},{"key":"bib77-20210131","first-page":"700","article-title":"Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion","volume":"85","year":"2003","journal-title":"J Bone Joint Surg Br."},{"key":"bib78-20210131","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/00005131-199509060-00005","article-title":"Fracture healing and mast cells","volume":"9","year":"1995","journal-title":"J Orthop Trauma."},{"key":"bib79-20210131","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/BF03016531","article-title":"High dose nonsteroidal anti-inflammatory drugs compromise spinal fusion","volume":"52","year":"2005","journal-title":"Can J Anaesth."},{"key":"bib80-20210131","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/art.21170","article-title":"Nonsteroidal antiinflammatory drugs and nonunion of humeral shaft fractures","volume":"53","year":"2005","journal-title":"Arthritis Rheum."},{"key":"bib81-20210131","first-page":"740","article-title":"Effects of local infusion of OP-1 on particle-induced and NSAID-induced inhibition of bone ingrowth in vivo","volume":"79","year":"2006","journal-title":"J Biomed Mater Res A."},{"key":"bib82-20210131","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1080\/00016470310014021","article-title":"COX inhibitors and bone healing","volume":"74","year":"2003","journal-title":"Acta Orthop Scand."},{"key":"bib83-20210131","doi-asserted-by":"crossref","first-page":"114","DOI":"10.2106\/00004623-200701000-00016","article-title":"Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment","volume":"89","year":"2007","journal-title":"J Bone Joint Surg Am."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004623-201205020-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:28:02Z","timestamp":1787750882000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004623-201205020-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,2]]},"references-count":81,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.j.01743","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,2]]}}}