{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:23:37Z","timestamp":1787754217454,"version":"build-2784847793"},"reference-count":53,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10,2]]},"DOI":"10.2106\/jbjs.l.01328","type":"journal-article","created":{"date-parts":[[2013,10,2]],"date-time":"2013-10-02T17:49:42Z","timestamp":1380736182000},"page":"1801-1811","source":"Crossref","is-referenced-by-count":84,"title":["Prevention of Venous Thromboembolic Disease After Total Hip and Knee Arthroplasty"],"prefix":"10.2106","volume":"95","author":[{"given":"Jay R.","family":"Lieberman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Pensak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"9","key":"bib1-20210131","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.2106\/00004623-200509000-00025","article-title":"Prevention of venous thromboembolic disease after total hip and knee arthroplasty","volume":"87","year":"2005 Sep","journal-title":"J Bone Joint Surg Am."},{"issue":"12","key":"bib2-20210131","doi-asserted-by":"crossref","first-page":"777","DOI":"10.5435\/00124635-201112000-00008","article-title":"AAOS clinical practice guideline: preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty","volume":"19","year":"2011 Dec","journal-title":"J Am Acad Orthop Surg."},{"issue":"2 Suppl","key":"bib3-20210131","first-page":"e278S","article-title":"Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","year":"2012 Feb","journal-title":"Chest."},{"issue":"7","key":"bib4-20210131","first-page":"1756","article-title":"American academy of orthopaedic surgeons clinical practice guideline on. Prevention of symptomatic pulmonary embolism in patients undergoing total hip or knee arthroplasty","volume":"91","year":"2009 Jul","journal-title":"J Bone Joint Surg Am."},{"issue":"12","key":"bib5-20210131","doi-asserted-by":"crossref","first-page":"717","DOI":"10.5435\/00124635-201112000-00001","article-title":"The new AAOS clinical practice guidelines on venous thromboembolic prophylaxis: how to adapt them to your practice","volume":"19","year":"2011 Dec","journal-title":"J Am Acad Orthop Surg."},{"issue":"12","key":"bib6-20210131","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1161\/CIRCULATIONAHA.108.813667","article-title":"Safety of short-term discontinuation of antiplatelet therapy in patients with drug-eluting stents","volume":"119","year":"2009 Mar 31","journal-title":"Circulation."},{"issue":"6","key":"bib7-20210131","doi-asserted-by":"crossref","first-page":"333","DOI":"10.5435\/JAAOS-20-06-333","article-title":"American College of Chest Physicians evidence-based guidelines for venous thromboembolic prophylaxis: the guideline wars are over","volume":"20","year":"2012 Jun","journal-title":"J Am Acad Orthop Surg."},{"issue":"6 Suppl","key":"bib8-20210131","first-page":"381S","article-title":"Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)","volume":"133","year":"2008 Jun","journal-title":"Chest."},{"issue":"2 Suppl","key":"bib9-20210131","first-page":"53S","article-title":"Methodology for the development of antithrombotic therapy and prevention of thrombosis guidelines: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","year":"2012 Feb","journal-title":"Chest."},{"issue":"9212","key":"bib10-20210131","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/S0140-6736(00)02110-3","article-title":"Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial","volume":"355","year":"2000 Apr 15","journal-title":"Lancet."},{"issue":"19","key":"bib11-20210131","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1056\/NEJM199311043291902","article-title":"A comparison of subcutaneous low-molecular-weight heparin with warfarin sodium for prophylaxis against deep-vein thrombosis after hip or knee implantation","volume":"329","year":"1993 Nov 4","journal-title":"N Engl J Med."},{"issue":"6","key":"bib12-20210131","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1055\/s-0038-1649959","article-title":"Subcutaneous low-molecular weight heparin or oral anticoagulants for the prevention of deep-vein thrombosis in elective hip and knee replacement? Fraxiparine Oral Anticoagulant Study Group","volume":"74","year":"1995 Dec","journal-title":"Thromb Haemost."},{"issue":"8","key":"bib13-20210131","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.2106\/00004623-199408000-00008","article-title":"RD heparin compared with warfarin for prevention of venous thromboembolic disease following total hip or knee arthroplasty","volume":"76","year":"1994 Aug","journal-title":"J Bone Joint Surg Am."},{"issue":"9","key":"bib14-20210131","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.2106\/00004623-199709000-00011","article-title":"Prevention of deep-vein thrombosis after total hip arthroplasty. Comparison of warfarin and dalteparin","volume":"79","year":"1997 Sep","journal-title":"J Bone Joint Surg Am."},{"issue":"7","key":"bib15-20210131","doi-asserted-by":"crossref","first-page":"932","DOI":"10.2106\/00004623-199907000-00005","article-title":"Comparison of enoxaparin and warfarin for the prevention of venous thromboembolic disease after total hip arthroplasty. Evaluation during hospitalization and three months after discharge","volume":"81","year":"1999 Jul","journal-title":"J Bone Joint Surg Am."},{"issue":"7","key":"bib16-20210131","doi-asserted-by":"crossref","first-page":"619","DOI":"10.7326\/0003-4819-124-7-199604010-00001","article-title":"Prevention of venous thromboembolism after knee arthroplasty. A randomized, double-blind trial comparing enoxaparin with warfarin","volume":"124","year":"1996 Apr 1","journal-title":"Ann Intern Med."},{"issue":"1","key":"bib17-20210131","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1055\/s-0038-1655902","article-title":"Efficacy and safety of low molecular weight heparin (ardeparin sodium) compared to warfarin for the prevention of venous thromboembolism after total knee replacement surgery: a double-blind, dose-ranging study","volume":"77","year":"1997 Jan","journal-title":"Thromb Haemost."},{"issue":"6","key":"bib18-20210131","doi-asserted-by":"crossref","first-page":"900","DOI":"10.2106\/00004623-200106000-00012","article-title":"Prevention of venous thromboembolic disease following primary total knee arthroplasty. A randomized, multicenter, open-label, parallel-group comparison of enoxaparin and warfarin","volume":"83","year":"2001 Jun","journal-title":"J Bone Joint Surg Am."},{"issue":"4 Suppl","key":"bib19-20210131","first-page":"337S","article-title":"Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety","volume":"102","year":"1992 Oct","journal-title":"Chest."},{"issue":"1","key":"bib20-20210131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1182\/blood.V79.1.1.1","article-title":"Low molecular weight heparin","volume":"79","year":"1992 Jan 1","journal-title":"Blood."},{"issue":"4","key":"bib21-20210131","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1055\/s-2002-34309","article-title":"The synthetic pentasaccharide fondaparinux: first in the class of antithrombotic agents that selectively inhibit coagulation factor Xa","volume":"28","year":"2002 Aug","journal-title":"Semin Thromb Hemost."},{"issue":"1","key":"bib22-20210131","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0049-3848(88)90279-4","article-title":"The inhibition of the generation of thrombin and the antithrombotic effect of a pentasaccharide with sole anti-factor Xa activity","volume":"51","year":"1988 Jul 1","journal-title":"Thromb Res."},{"issue":"9319","key":"bib23-20210131","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1016\/S0140-6736(02)08652-X","article-title":"Postoperative fondaparinux versus preoperative enoxaparin for prevention of venous thromboembolism in elective hip-replacement surgery: a randomised double-blind comparison","volume":"359","year":"2002 May 18","journal-title":"Lancet."},{"issue":"9319","key":"bib24-20210131","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/S0140-6736(02)08648-8","article-title":"Postoperative fondaparinux versus postoperative enoxaparin for prevention of venous thromboembolism after elective hip-replacement surgery: a randomised double-blind trial","volume":"359","year":"2002 May 18","journal-title":"Lancet."},{"issue":"18","key":"bib25-20210131","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1056\/NEJMoa011099","article-title":"Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery","volume":"345","year":"2001 Nov 1","journal-title":"N Engl J Med."},{"issue":"26","key":"bib26-20210131","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1056\/NEJMoa0800374","article-title":"Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty","volume":"358","year":"2008 Jun 26","journal-title":"N Engl J Med."},{"issue":"9632","key":"bib27-20210131","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(08)60880-6","article-title":"Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial","volume":"372","year":"2008 Jul 5","journal-title":"Lancet."},{"issue":"26","key":"bib28-20210131","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1056\/NEJMoa076016","article-title":"Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty","volume":"358","year":"2008 Jun 26","journal-title":"N Engl J Med."},{"issue":"9676","key":"bib29-20210131","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/S0140-6736(09)60734-0","article-title":"Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial","volume":"373","year":"2009 May 16","journal-title":"Lancet."},{"issue":"1","key":"bib30-20210131","first-page":"91","article-title":"Return to theatre following total hip and knee replacement, before and after the introduction of rivaroxaban: a retrospective cohort study","volume":"93","year":"2011 Jan","journal-title":"J Bone Joint Surg Br."},{"issue":"26","key":"bib31-20210131","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1056\/NEJMoa1006885","article-title":"Apixaban versus enoxaparin for thromboprophylaxis after hip replacement","volume":"363","year":"2010 Dec 23","journal-title":"N Engl J Med."},{"issue":"6","key":"bib32-20210131","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1056\/NEJMoa0810773","article-title":"Apixaban or enoxaparin for thromboprophylaxis after knee replacement","volume":"361","year":"2009 Aug 6","journal-title":"N Engl J Med."},{"issue":"9717","key":"bib33-20210131","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S0140-6736(09)62125-5","article-title":"Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial","volume":"375","year":"2010 Mar 6","journal-title":"Lancet."},{"issue":"9591","key":"bib34-20210131","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0140-6736(07)61445-7","article-title":"Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial","volume":"370","year":"2007 Sep 15","journal-title":"Lancet."},{"issue":"4","key":"bib35-20210131","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1160\/TH10-10-0679","article-title":"Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II*). A randomised, double-blind, non-inferiority trial","volume":"105","year":"2011 Apr","journal-title":"Thromb Haemost."},{"issue":"11","key":"bib36-20210131","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1111\/j.1538-7836.2007.02748.x","article-title":"Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial","volume":"5","year":"2007 Nov","journal-title":"J Thromb Haemost."},{"issue":"1","key":"bib37-20210131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.arth.2008.01.132","article-title":"Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery","volume":"24","year":"2009 Jan","journal-title":"J Arthroplasty."},{"issue":"Suppl","key":"bib38-20210131","first-page":"S29","article-title":"Prospective randomized trial of sequential compression devices vs low-dose warfarin for deep venous thrombosis prophylaxis in total hip arthroplasty","volume":"6","year":"1991","journal-title":"J Arthroplasty."},{"issue":"1","key":"bib39-20210131","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0883-5403(87)80027-X","article-title":"Low-dose warfarin versus external pneumatic compression for prophylaxis against venous thromboembolism following total hip replacement","volume":"2","year":"1987","journal-title":"J Arthroplasty."},{"issue":"21","key":"bib40-20210131","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1001\/jama.1992.03480210073035","article-title":"Comparison of warfarin and external pneumatic compression in prevention of venous thrombosis after total hip replacement","volume":"267","year":"1992 Jun 3","journal-title":"JAMA."},{"issue":"269","key":"bib41-20210131","first-page":"89","article-title":"Intermittent pneumatic compression versus coumadin. Prevention of deep vein thrombosis in lower-extremity total joint arthroplasty","year":"1991 Aug","journal-title":"Clin Orthop Relat Res."},{"issue":"1","key":"bib42-20210131","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2106\/00004623-199072010-00005","article-title":"Pneumatic sequential-compression boots compared with aspirin prophylaxis of deep-vein thrombosis after total knee arthroplasty","volume":"72","year":"1990 Jan","journal-title":"J Bone Joint Surg Am."},{"issue":"6213","key":"bib43-20210131","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1136\/bmj.280.6213.514","article-title":"Prevention of venous thromboembolism after total knee replacement by high-dose aspirin or intermittent calf and thigh compression","volume":"280","year":"1980 Feb 23","journal-title":"Br Med J."},{"issue":"1-2","key":"bib44-20210131","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0049-3848(79)90267-6","article-title":"Effectiveness of intermittent pulsatile elastic stockings for the prevention of calf and thigh vein thrombosis in patients undergoing elective knee surgery","volume":"16","year":"1979","journal-title":"Thromb Res."},{"issue":"4","key":"bib45-20210131","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1302\/0301-620X.81B4.0810654","article-title":"Prevention of deep-vein thrombosis after total knee replacement. Randomised comparison between a low-molecular-weight heparin (nadroparin) and mechanical prophylaxis with a foot-pump system","volume":"81","year":"1999 Jul","journal-title":"J Bone Joint Surg Br."},{"issue":"3","key":"bib46-20210131","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0883-5403(99)90060-8","article-title":"Sequential foot compression reduces lower limb swelling and pain after total knee arthroplasty","volume":"14","year":"1999 Apr","journal-title":"J Arthroplasty."},{"issue":"6","key":"bib47-20210131","doi-asserted-by":"crossref","first-page":"826","DOI":"10.2106\/00004623-199606000-00004","article-title":"Prophylaxis against deep venous thrombosis after total knee arthroplasty. Pneumatic plantar compression and aspirin compared with aspirin alone","volume":"78","year":"1996 Jun","journal-title":"J Bone Joint Surg Am."},{"issue":"8","key":"bib48-20210131","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.2106\/00004623-199808000-00009","article-title":"Comparison of the use of a foot pump with the use of low-molecular-weight heparin for the prevention of deep-vein thrombosis after total hip replacement. A prospective, randomized trial","volume":"80","year":"1998 Aug","journal-title":"J Bone Joint Surg Am."},{"issue":"8","key":"bib49-20210131","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.arth.2007.11.006","article-title":"Portable compression device and low-molecular-weight heparin compared with low-molecular-weight heparin for thromboprophylaxis after total joint arthroplasty","volume":"23","year":"2008 Dec","journal-title":"J Arthroplasty."},{"issue":"5","key":"bib50-20210131","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.2106\/00004623-200705000-00018","article-title":"Rapid-inflation intermittent pneumatic compression for prevention of deep venous thrombosis","volume":"89","year":"2007 May","journal-title":"J Bone Joint Surg Am."},{"issue":"6","key":"bib51-20210131","first-page":"809","article-title":"Prevention of deep-vein thrombosis after total hip and knee replacement. Low-molecular-weight heparin in combination with intermittent pneumatic compression","volume":"86","year":"2004 Aug","journal-title":"J Bone Joint Surg Br."},{"issue":"3","key":"bib52-20210131","doi-asserted-by":"crossref","first-page":"527","DOI":"10.2106\/JBJS.I.00047","article-title":"Thrombosis prevention after total hip arthroplasty: a prospective, randomized trial comparing a mobile compression device with low-molecular-weight heparin","volume":"92","year":"2010 Mar","journal-title":"J Bone Joint Surg Am."},{"issue":"3","key":"bib53-20210131","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1086\/505220","article-title":"The surgical infection prevention and surgical care improvement projects: national initiatives to improve outcomes for patients having surgery","volume":"43","year":"2006 Aug 1","journal-title":"Clin Infect Dis."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004623-201310020-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:24:10Z","timestamp":1787750650000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004623-201310020-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,2]]},"references-count":53,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.l.01328","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,2]]}}}