{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:39:52Z","timestamp":1787755192012,"version":"build-2784847793"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Acute compartment syndrome of the foot is a controversial topic. Release of the foot has been seen as complicated because of large incisions and postoperative morbidity, and there has been debate over whether this procedure is actually effective for releasing all areas of increased pressure. New sensor technology affords the opportunity to advance our understanding of acute compartment syndrome of the foot and its treatment. The purpose of the present study was to determine whether percutaneous decompression could be performed for the treatment of compartment syndrome in a forefoot model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The present study utilized a validated continuous pressure sensor to model compartment syndrome in human cadaveric feet. We utilized a pressure-controlled saline solution infusion system to induce increased pressure. A novel percutaneous release of the forefoot was investigated to assess its efficacy in achieving decompression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>For all cadaveric specimens, continuous pressure monitoring was accomplished with use of a continuous pressure sensor. There were 4 discrete compartment areas that could be reliably pressurized in all feet. The average baseline, pressurized, and post-release pressures (and standard deviations) were 4.5 \u00b1 2.9, 43.8 \u00b1 7.7, and 9.5 \u00b1 3.6 mm Hg, respectively. Percutaneous decompression produced a significant decrease in pressure in all 4 compartments (p &lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>With use of continuous compartment pressure monitoring, 4 consistent areas were established as discrete compartments in the foot. All 4 compartments were pressurized with a standard pump system. With use of 2 small dorsal incisions, all 4 compartments were successfully released, with no injuries identified in the cutaneous nerve branches, extensor tendons, or arteries. These results have strong implications for the future of modeling compartment syndrome as well as for guiding clinical studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>A reproducible and accurate method of continuous pressure monitoring of foot compartments after trauma is needed (1) to reliably identify patients who are likely to benefit from compartment release and (2) to help avoid missed or evolving cases of acute compartment syndrome. In addition, a reproducible method for percutaneous compartment release that minimizes collateral structural damage and the need for secondary surgical procedures is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.oa.21.00040","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T17:16:29Z","timestamp":1637687789000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Percutaneous Forefoot Decompression in a Foot Compartment Syndrome Model"],"prefix":"10.2106","volume":"6","author":[{"given":"Drew E.","family":"Schupbach","sequence":"first","affiliation":[{"name":"Experimental Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9487-3042","authenticated-orcid":false,"given":"Mohamad","family":"Nasser Eddine","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Orthopedic Surgery, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1467-0366","authenticated-orcid":false,"given":"Yazan","family":"Honjol","sequence":"additional","affiliation":[{"name":"Experimental Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"Merle","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Orthopedic Surgery, McGill University, Montreal, Quebec, Canada"},{"name":"Department of Chemical Engineering, Polytechnique Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3934-8920","authenticated-orcid":false,"given":"Edward J.","family":"Harvey","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Orthopedic Surgery, McGill University, Montreal, Quebec, Canada"},{"name":"Injury Repair and Recovery Program, McGill University Health Centre Research Institute, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,10]]},"reference":[{"issue":"6","key":"R1-20240801","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1177\/096721090201000620","article-title":"The pathophysiology of skeletal muscle ischemia and the reperfusion syndrome: a review","volume":"10","author":"Blaisdell","year":"2002","journal-title":"Cardiovasc Surg"},{"issue":"12","key":"R2-20240801","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1097\/BOT.0b013e31826df980","article-title":"What\u2019s new in acute compartment syndrome?","volume":"26","author":"Harvey","year":"2012","journal-title":"J Orthop 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