{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:50:26Z","timestamp":1787755826326,"version":"build-2784847793"},"reference-count":71,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The most common reason for lower-extremity amputations remains the management of complications of diabetes mellitus (DM) and\/or peripheral vascular disease. Traditional socket prostheses remain the rehabilitation standard, although transcutaneous osseointegration for amputees (TOFA) is proving a viable alternative. Limited studies of TOFA for vascular amputees have been published, but no study has focused on TOFA for patients with DM, neglecting this important patient population. The primary aim of the present study exploring this potential care option was to report the frequencies and types of adverse events following TOFA for patients with well-controlled DM. The secondary aims were to report their mobility and quality-of-life changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective review was performed of 17 consecutive patients with well-controlled DM who had undergone unilateral transfemoral TOFA from 2013 to 2019 and had been followed for at least 2 years. Outcomes were perioperative complications, additional surgery (soft-tissue refashioning, debridement, implant removal, periprosthetic fracture treatment), mobility (daily prosthesis wear hours, K-level, Timed Up and Go Test, 6-Minute Walk Test), and patient-reported outcomes (Questionnaire for Persons with a Transfemoral Amputation, Short Form-36).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There were no perioperative systemic complications, deaths, or proximal amputations. Two patients (12%) sustained a periprosthetic fracture following a fall, managed by internal fixation with implant retention, and regained independent ambulation. Eight patients (47%) had additional surgery or surgeries for non-traumatic complications: 4 (24%) had soft-tissue refashioning, 3 (18%) had debridement, and 3 others had implant removal with subsequent revision osseointegration for aseptic loosening (1) or infection (2). The proportion of patients wearing their prosthesis at least 8 hours daily improved from 5 (36%) to 11 (79%) of 14 (p = 0.054). The proportion of patients who achieved at least K-level 2 improved from 6% to 94% (p &lt; 0.001). Other changes were not significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Contraindicating TOFA for all patients with DM seems draconian. Patients with well-controlled DM experienced significant mobility improvements, although additional surgery was somewhat common. Improvements in selection criteria or surgical technique to reduce risks are needed so that TOFA can be routinely considered for amputees with well-controlled DM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Therapeutic\n                      <jats:underline>Level IV<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.oa.23.00168","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T14:01:53Z","timestamp":1733148113000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Transfemoral Osseointegration for Amputees with Well-Managed Diabetes Mellitus"],"prefix":"10.2106","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7065-0656","authenticated-orcid":false,"given":"Jason S.","family":"Hoellwarth","sequence":"first","affiliation":[{"name":"Osseointegration Limb Replacement Center, Limb Lengthening and Complex Reconstruction Service, Hospital for Special Surgery, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5760-6466","authenticated-orcid":false,"given":"Shakib","family":"Al-Jawazneh","sequence":"additional","affiliation":[{"name":"Limb Reconstruction Centre, Macquarie University Hospital, Macquarie University, Macquarie Park, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5201-4058","authenticated-orcid":false,"given":"Atiya","family":"Oomatia","sequence":"additional","affiliation":[{"name":"Limb Reconstruction Centre, Macquarie University Hospital, Macquarie University, Macquarie Park, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3069-4141","authenticated-orcid":false,"given":"Kevin","family":"Tetsworth","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Royal Brisbane and Women\u2019s Hospital, Herston, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munjed","family":"Al Muderis","sequence":"additional","affiliation":[{"name":"Limb Reconstruction Centre, Macquarie University Hospital, Macquarie University, Macquarie Park, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10]]},"reference":[{"issue":"1","key":"R1-20250310","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1053\/j.semvascsurg.2021.02.011","article-title":"The epidemiology of lower extremity amputations, strategies for amputation prevention, and the importance of patient-centered care","volume":"34","author":"Bernatchez","year":"2021","journal-title":"Semin Vasc Surg"},{"issue":"3","key":"R2-20250310","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1046\/j.1365-2168.2000.01344.x","article-title":"Epidemiology of lower extremity amputation in centres in Europe, North America and East Asia","volume":"87","author":"Unwin","year":"2000","journal-title":"Br J Surg"},{"issue":"2","key":"R3-20250310","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.jvs.2011.01.046","article-title":"Defining successful mobility after lower extremity amputation for complications of peripheral vascular disease and diabetes","volume":"54","author":"Norvell","year":"2011","journal-title":"J Vasc Surg"},{"issue":"5","key":"R4-20250310","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1365-4632.2008.03604.x","article-title":"Skin problems in amputees: a descriptive study","volume":"47","author":"Koc","year":"2008","journal-title":"Int J Dermatol"},{"issue":"2","key":"R5-20250310","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2340\/00015555-1040","article-title":"Skin problems of the stump in lower limb amputees: 1. A clinical study","volume":"91","author":"Meulenbelt","year":"2011","journal-title":"Acta Derm Venereol"},{"issue":"8","key":"R6-20250310","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1682\/JRRD.2010.09.0189","article-title":"Residual limb volume change: systematic review of measurement and management","volume":"48","author":"Sanders","year":"2011","journal-title":"J Rehabil Res Dev"},{"issue":"8","key":"R7-20250310","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/00002060-200108000-00003","article-title":"Use and satisfaction with prosthetic devices among persons with trauma-related amputations: a long-term outcome study","volume":"80","author":"Dillingham","year":"2001","journal-title":"Am J Phys Med Rehabil"},{"issue":"3","key":"R8-20250310","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1080\/03093640208726650","article-title":"A comparison of traditional prosthetic training versus proprioceptive neuromuscular facilitation resistive gait training with trans-femoral amputees","volume":"26","author":"Yi\u011fiter","year":"2002","journal-title":"Prosthet Orthot Int"},{"issue":"1","key":"R9-20250310","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.hkpj.2013.02.002","article-title":"Efficacy of proprioceptive neuromuscular facilitation techniques versus traditional prosthetic training for improving ambulatory function in transtibial amputees","volume":"32","author":"Sahay","year":"2014","journal-title":"Hong Kong Physiother J"},{"issue":"3","key":"R10-20250310","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1053\/j.jfas.2016.01.012","article-title":"Mortality After Nontraumatic Major Amputation Among Patients With Diabetes and Peripheral Vascular Disease: A Systematic Review","volume":"55","author":"Thorud","year":"2016","journal-title":"J Foot Ankle Surg"},{"issue":"8","key":"R11-20250310","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.apmr.2015.04.001","article-title":"Suicidal ideation among individuals with dysvascular lower extremity amputation","volume":"96","author":"Turner","year":"2015","journal-title":"Arch Phys Med Rehabil"},{"issue":"3","key":"R12-20250310","doi-asserted-by":"crossref","first-page":"e0043","DOI":"10.2106\/JBJS.RVW.19.00043","article-title":"Osseointegration for Amputees: Current Implants, Techniques, and Future Directions","volume":"8","author":"Hoellwarth","year":"2020","journal-title":"JBJS Rev"},{"issue":"22","key":"R13-20250310","doi-asserted-by":"crossref","first-page":"e977","DOI":"10.5435\/JAAOS-D-19-00016","article-title":"Orthopaedic Osseointegration: State of the Art","volume":"27","author":"Zaid","year":"2019","journal-title":"J Am Acad Orthop Surg"},{"issue":"10","key":"R14-20250310","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.2106\/JBJS.RVW.17.00037","article-title":"Osseointegration for Lower-Limb Amputation: A Systematic Review of Clinical Outcomes","volume":"5","author":"Hebert","year":"2017","journal-title":"JBJS Rev"},{"issue":"11","key":"R15-20250310","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1016\/j.apmr.2013.05.020","article-title":"Walking ability and quality of life in subjects with transfemoral amputation: a comparison of osseointegration with socket prostheses","volume":"94","author":"Van de Meent","year":"2013","journal-title":"Arch Phys Med Rehabil"},{"issue":"3","key":"R16-20250310","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1682\/JRRD.2008.06.0080","article-title":"One hundred patients treated with osseointegrated transfemoral amputation prostheses--rehabilitation perspective","volume":"46","author":"Hagberg","year":"2009","journal-title":"J Rehabil Res Dev"},{"issue":"12","key":"R17-20250310","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1007\/s11999-017-5507-2","article-title":"Osteomyelitis Risk in Patients With Transfemoral Amputations Treated With Osseointegration Prostheses","volume":"475","author":"Tillander","year":"2017","journal-title":"Clin Orthop Relat Res"},{"issue":"5","key":"R18-20250310","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s00064-011-0054-6","article-title":"Implantation of the endo-exo femur prosthesis to improve the mobility of amputees","volume":"23","author":"Aschoff","year":"2011","journal-title":"Oper Orthop Traumatol"},{"issue":"2","key":"R19-20250310","first-page":"e20","article-title":"Transtibial Osseointegration for Patients with Peripheral Vascular Disease: A Case Series of 6 Patients with Minimum 3-Year Follow-up","volume":"6","author":"Akhtar","year":"2021","journal-title":"JB JS Open Access"},{"issue":"18","key":"R20-20250310","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.2106\/JBJS.16.01295","article-title":"Osseointegrated transtibial implants in patients with peripheral vascular disease: A multicenter case series of 5 patients with 1-year follow-up","volume":"99","author":"Atallah","year":"2017","journal-title":"J Bone Joint Surg Am"},{"issue":"3","key":"R21-20250310","doi-asserted-by":"crossref","first-page":"e013508","DOI":"10.1136\/bmjopen-2016-013508","article-title":"Single-stage osseointegrated reconstruction and rehabilitation of lower limb amputees: the Osseointegration Group of Australia Accelerated Protocol-2 (OGAAP-2) for a prospective cohort study","volume":"7","author":"Al Muderis","year":"2017","journal-title":"BMJ Open"},{"issue":"10","key":"R22-20250310","doi-asserted-by":"crossref","first-page":"e038346","DOI":"10.1136\/bmjopen-2020-038346","article-title":"Osseointegrated reconstruction and rehabilitation of transtibial amputees: the Osseointegration Group of Australia surgical technique and protocol for a prospective cohort study","volume":"10","author":"Haque","year":"2020","journal-title":"BMJ Open"},{"issue":"3","key":"R24-20250310","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/00006416-200605000-00015","article-title":"Diabetes and diabetes medications","volume":"25","author":"Turkoski","year":"2006","journal-title":"Orthop Nurs"},{"issue":"2","key":"R25-20250310","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.2106\/JBJS.ST.21.00068","article-title":"Revision Amputation with Press-Fit Osseointegration for Transfemoral Amputees","volume":"12","author":"Hoellwarth","year":"2022","journal-title":"JBJS Essent Surg Tech"},{"issue":"5","key":"R26-20250310","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1682\/JRRD.2003.11.0167","article-title":"Questionnaire for Persons with a Transfemoral Amputation (Q-TFA): initial validity and reliability of a new outcome measure","volume":"41","author":"Hagberg","year":"2004","journal-title":"J Rehabil Res Dev"},{"issue":"1","key":"R27-20250310","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s12603-009-0010-4","article-title":"The SF-36: a simple, effective measure of mobility-disability for epidemiological studies","volume":"13","author":"Syddall","year":"2009","journal-title":"J Nutr Health Aging"},{"issue":"7","key":"R28-20250310","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0003-9993(99)90234-4","article-title":"The Timed \u201cup and go\u201d test: reliability and validity in persons with unilateral lower limb amputation","volume":"80","author":"Schoppen","year":"1999","journal-title":"Arch Phys Med Rehabil"},{"issue":"6329","key":"R29-20250310","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1136\/bmj.284.6329.1607","article-title":"Two-, six-, and 12-minute walking tests in respiratory disease","volume":"284","author":"Butland","year":"1982","journal-title":"Br Med J (Clin Res Ed)."},{"issue":"12","key":"R31-20250310","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1097\/PHM.0000000000000796","article-title":"Standard and Amputation-Adjusted Body Mass Index Measures: Comparison and Relevance to Functional Measures, Weight-Related Comorbidities, and Dieting","volume":"96","author":"Wong","year":"2017","journal-title":"Am J Phys Med Rehabil"},{"issue":"2","key":"R32-20250310","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1302\/0301-620X.102B2.BJJ-2019-0697.R2","article-title":"Periprosthetic osseointegration fractures are infrequent and management is familiar","volume":"102-B","author":"Hoellwarth","year":"2020","journal-title":"Bone Joint J"},{"issue":"3","key":"R33-20250310","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.CC.21.00778","article-title":"Periprosthetic Femur Fractures in Osseointegration Amputees: A Report of 2 Cases Using a Modified Traction Technique","volume":"12","author":"Hoellwarth","year":"2022","journal-title":"JBJS Case Connect"},{"issue":"1","key":"R34-20250310","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1302\/0301-620X.102B1.BJJ-2019-0611.R1","article-title":"A 15-year follow-up of transfemoral amputees with bone-anchored transcutaneous prostheses","volume":"102-B","author":"Hagberg","year":"2020","journal-title":"Bone Joint J"},{"issue":"6","key":"R35-20250310","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00132-015-3117-9","article-title":"[Endo-exo prostheses following limb-amputation]","volume":"44","author":"Juhnke","year":"2015","journal-title":"Orthopade"},{"issue":"1","key":"R36-20250310","doi-asserted-by":"crossref","first-page":"24","DOI":"10.2337\/diacare.12.1.24","article-title":"Lower-extremity amputation in people with diabetes. Epidemiology and prevention","volume":"12","author":"Bild","year":"1989","journal-title":"Diabetes Care"},{"issue":"4","key":"R37-20250310","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1586\/17446651.2015.1058151","article-title":"Reducing diabetic limb amputations in developing countries","volume":"10","author":"Abbas","year":"2015","journal-title":"Expert Rev Endocrinol Metab"},{"issue":"10","key":"R38-20250310","first-page":"e3418","article-title":"Review of Socioeconomic Disparities in Lower Extremity Amputations: A Continuing Healthcare Problem in the United States","volume":"10","author":"Girijala","year":"2018","journal-title":"Cureus"},{"issue":"11","key":"R39-20250310","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.2522\/ptj.20080020","article-title":"Epidemiology of diabetes and diabetes-related complications","volume":"88","author":"Deshpande","year":"2008","journal-title":"Phys Ther"},{"issue":"2","key":"R40-20250310","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1503\/cjs.013115","article-title":"A Canadian population-based description of the indications for lower-extremity amputations and outcomes","volume":"59","author":"Kayssi","year":"2016","journal-title":"Can J Surg"},{"issue":"9","key":"R41-20250310","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/j.apmr.2005.03.025","article-title":"Changing dynamics in lower-extremity amputation in China","volume":"86","author":"Wan-Nar Wong","year":"2005","journal-title":"Arch Phys Med Rehabil"},{"issue":"4","key":"R42-20250310","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-277X.2010.01061.x","article-title":"Diet and exercise in the prevention of diabetes","volume":"23","author":"Walker","year":"2010","journal-title":"J Hum Nutr Diet"},{"issue":"2","key":"R43-20250310","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.sapharm.2010.03.002","article-title":"Relationship between diet, exercise habits, and health status among patients with diabetes","volume":"7","author":"Campbell","year":"2011","journal-title":"Res Social Adm Pharm"},{"issue":"9","key":"R44-20250310","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1097\/PHM.0000000000001925","article-title":"Mobility Analysis of AmpuTees (MAAT 7): Normative Mobility Values for Lower Limb Prosthesis Users of Varying Age, Etiology, and Amputation Level","volume":"101","author":"England","year":"2022","journal-title":"Am J Phys Med Rehabil"},{"key":"R45-20250310","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.diabres.2017.10.030","article-title":"Diabetes-related amputations create considerable public health burden in the UK","volume":"135","author":"Graz","year":"2018","journal-title":"Diabetes Res Clin Pract"},{"issue":"17","key":"R46-20250310","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1080\/09638280701320797","article-title":"Return to work after lower limb amputation","volume":"29","author":"Burger","year":"2007","journal-title":"Disabil Rehabil"},{"issue":"10","key":"R47-20250310","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1080\/09638280500265219","article-title":"Predictors of return to work following traumatic work-related lower extremity amputation","volume":"28","author":"Hebert","year":"2006","journal-title":"Disabil Rehabil"},{"issue":"4","key":"R48-20250310","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1007\/s10926-018-9757-y","article-title":"Factors Influencing Functional Outcomes and Return-to-Work After Amputation: A Review of the Literature","volume":"28","author":"Darter","year":"2018","journal-title":"J Occup Rehabil"},{"issue":"10","key":"R49-20250310","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1053\/apmr.2001.26074","article-title":"Factors related to successful job reintegration of people with a lower limb amputation","volume":"82","author":"Schoppen","year":"2001","journal-title":"Arch Phys Med Rehabil"},{"key":"R50-20250310","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.gaitpost.2018.05.023","article-title":"Peak pressure data and pressure-time integral in the contralateral limb in patients with diabetes and a trans-tibial prosthesis","volume":"64","author":"Borg","year":"2018","journal-title":"Gait Posture"},{"issue":"1","key":"R51-20250310","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/JPO.0b013e3181ccc53d","article-title":"Functional Outcome of Transfemoral Amputees Fitted With an Osseointegrated Fixation: Temporal Gait Characteristics","volume":"22","author":"Frossard","year":"2010","journal-title":"J Prosthet Orthot"},{"key":"R52-20250310","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.gaitpost.2022.12.011","article-title":"Osseointegrated prostheses improve balance and balance confidence in individuals with unilateral transfemoral limb loss","volume":"100","author":"Gaffney","year":"2023","journal-title":"Gait Posture"},{"issue":"2","key":"R53-20250310","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3109\/03093641003645528","article-title":"Prosthetic liners for lower limb amputees: a review of the literature","volume":"34","author":"Klute","year":"2010","journal-title":"Prosthet Orthot Int"},{"issue":"11","key":"R54-20250310","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/01720610-200711010-00017","article-title":"Common skin pathology in LE prosthesis users","volume":"20","author":"Highsmith","year":"2007","journal-title":"JAAPA"},{"issue":"1","key":"R55-20250310","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1109\/JBHI.2014.2368774","article-title":"Skin Temperature Prediction in Lower Limb Prostheses","volume":"20","author":"Mathur","year":"2016","journal-title":"IEEE J Biomed Health Inform"},{"key":"R57-20250310","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.medengphy.2019.04.003","article-title":"A motor-driven adjustable prosthetic socket operated using a mobile phone app: A technical note","volume":"68","author":"Sanders","year":"2019","journal-title":"Med Eng Phys."},{"issue":"19","key":"R58-20250310","doi-asserted-by":"crossref","first-page":"6841","DOI":"10.3390\/app10196841","article-title":"Towards Management of Residual Limb Volume: Monitoring the Prosthetic Interface Pressure to Detect Volume Fluctuations\u2014A Feasibility Study","volume":"10","author":"Ahmadizadeh","year":"2020","journal-title":"Applied Sciences"},{"issue":"14","key":"R59-20250310","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1080\/09638288.2022.2093997","article-title":"Feasibility testing of a novel prosthetic socket sensor system","volume":"45","author":"Rich","year":"2023","journal-title":"Disabil Rehabil"},{"issue":"5","key":"R60-20250310","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1080\/17483107.2018.1479782","article-title":"The AirCirc: design and development of a thermal management prototype device for below-knee prosthesis leg socket","volume":"14","author":"Nurhanisah","year":"2019","journal-title":"Disabil Rehabil Assist Technol"},{"issue":"1","key":"R61-20250310","doi-asserted-by":"crossref","first-page":"35213","DOI":"10.33137\/cpoj.v4i1.35213","article-title":"Using a sweating residuum\/socket interface simulator for the evaluation of sweat management liners in lower limb prosthetics","volume":"4","author":"McGrath","year":"2021","journal-title":"Can Prosthet Orthot J"},{"issue":"4","key":"R62-20250310","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.pmr.2009.06.014","article-title":"Prosthetic rehabilitation issues in the diabetic and dysvascular amputee","volume":"20","author":"Uustal","year":"2009","journal-title":"Phys Med Rehabil Clin N Am"},{"issue":"S1","key":"R63-20250310","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1097\/SAP.0000000000002329","article-title":"Soft Tissue Contouring at the Time of Osseointegrated Implant Reconstruction for Lower Extremity Amputation","volume":"85","author":"Marano","year":"2020","journal-title":"Ann Plast Surg"},{"issue":"11","key":"R64-20250310","doi-asserted-by":"crossref","first-page":"900","DOI":"10.2106\/JBJS.15.00808","article-title":"Safety of osseointegrated implants for transfemoral amputees: A two-center prospective cohort study","volume":"98","author":"Al Muderis","year":"2016","journal-title":"J Bone Joint Surg Am"},{"issue":"4","key":"R65-20250310","doi-asserted-by":"crossref","first-page":"155","DOI":"10.5194\/jbji-7-155-2022","article-title":"Unexpected positive intraoperative cultures (UPIC) at index osseointegration do not lead to increased postoperative infectious events","volume":"7","author":"Hoellwarth","year":"2022","journal-title":"J Bone Jt Infect"},{"issue":"3","key":"R66-20250310","first-page":"e21","article-title":"Early Experience with Femoral and Tibial Bone-Anchored Osseointegration Prostheses","volume":"6","author":"Reif","year":"2021","journal-title":"JB JS Open Access"},{"issue":"10","key":"R67-20250310","doi-asserted-by":"crossref","first-page":"e2235074","DOI":"10.1001\/jamanetworkopen.2022.35074","article-title":"Association Between Osseointegration of Lower Extremity Amputation and Mortality Among Adults","volume":"5","author":"Hoellwarth","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"7S","key":"R68-20250310","doi-asserted-by":"crossref","first-page":"S337","DOI":"10.1016\/j.arth.2018.12.024","article-title":"Mortality During Total Hip Periprosthetic Joint Infection","volume":"34","author":"Natsuhara","year":"2019","journal-title":"J Arthroplasty"},{"issue":"1","key":"R69-20250310","first-page":"27","article-title":"Total joint arthroplasty: When do fatal or near-fatal complications occur?","volume":"89","author":"Parvizi","year":"2007","journal-title":"J Bone Joint Surg Am"},{"issue":"10016","key":"R70-20250310","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0140-6736(14)61798-0","article-title":"Periprosthetic joint infection","volume":"387","author":"Kapadia","year":"2016","journal-title":"Lancet"},{"issue":"5","key":"R71-20250310","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3109\/17453674.2015.1044389","article-title":"Diabetes is associated with persistent pain after hip and knee replacement","volume":"86","author":"Rajam\u00e4ki","year":"2015","journal-title":"Acta Orthop"},{"issue":"7","key":"R72-20250310","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1007\/s00402-021-03826-y","article-title":"Management, outcome, and novel classification system of periprosthetic fractures in patients with transcutaneous osseointegrated prosthetic systems (TOPS)-a retrospective cohort analysis","volume":"142","author":"\u00d6rgel","year":"2022","journal-title":"Arch Orthop Trauma Surg"},{"issue":"6","key":"R73-20250310","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.injury.2007.02.049","article-title":"Risk factors for periprosthetic femoral fracture","volume":"38","author":"Franklin","year":"2007","journal-title":"Injury"},{"issue":"6","key":"R75-20250310","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.amjsurg.2017.09.015","article-title":"Informed consent-It\u2019s more than a signature on a piece of paper","volume":"214","author":"Cocanour","year":"2017","journal-title":"Am J Surg"}],"container-title":["JBJS Open Access"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.OA.23.00168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:53:46Z","timestamp":1787752426000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.OA.23.00168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":71,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.oa.23.00168","relation":{},"ISSN":["2472-7245"],"issn-type":[{"value":"2472-7245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}