{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:19:13Z","timestamp":1787753953639,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Isolating the causative microorganism in patients with a periprosthetic joint infection (PJI) before revision surgery is critical to determine the right surgical and antibiotic strategy. A wide variety in concordance between p-SFC and intraoperative cultures is reported in the literature.<\/jats:p>\n                    <jats:p>The objective was to determine the incidence of discordance and analyze risk factors for discordance between a positive preoperative synovial culture and intraoperative cultures in revision arthroplasty for PJI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>An international multicenter retrospective observational cohort study was conducted including patients with septic total revision arthroplasty, between January 2020 and January 2024. Discordance and risk factors were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Discordance was 36% (n = 647). Risk factors for discordance were center specific: OR 4.22 (95% confidence interval [CI] 2.97-5.99), the presence of a sinus tract: odds ratio (OR) 1.80 (95% CI 1.22-2.66), and the hip joint: OR 1.61 (95% CI 1.12-2.30).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Discordance between positive preoperative synovial fluid culture and intraoperative cultures in revision arthroplasty is relatively high, center-specific, and less reliable in patients with hip arthroplasty and\/or a sinus tract.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.oa.26.00067","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T18:03:50Z","timestamp":1776362630000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Risk Factors for Discordance Between Synovial Fluid Culture and Intraoperative Cultures in Revision Arthroplasties"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3168-6562","authenticated-orcid":false,"given":"Karsten D.","family":"Ottink","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, the University of Groningen, Groningen, the Netherlands"},{"name":"Department of Orthopedic surgery, Spaarne Gasthuis Haarlem\/ Hoofddorp, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5118-9523","authenticated-orcid":false,"given":"Flaminia","family":"Olearo","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, Universit\u00e4ts-Krankenhaus Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9114-9537","authenticated-orcid":false,"given":"Danguole","family":"Vaznaisiene","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Lithuanian University of Health Sciences, Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1058-1307","authenticated-orcid":false,"given":"Tim","family":"Rolvien","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedic Surgery, Division of Orthopaedics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3201-3457","authenticated-orcid":false,"given":"Salma","family":"Kaoual","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology, Mohamed Kassab Institute of Orthopedics, Tunis, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4674-6953","authenticated-orcid":false,"given":"Elizabeth","family":"Morreel","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infection Prevention, Maastricht University Medical Center, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7391-3394","authenticated-orcid":false,"given":"Victoria","family":"B\u00eerlu\u0163iu","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, County Clinical Emergency Hospital, Sibiu, Roumania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1752-1382","authenticated-orcid":false,"given":"Joan","family":"G\u00f3mez-Junyent","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Hospital del Mar, Hospital del Mar Research Institute, Universitat Pompeu Fabra, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4483-677X","authenticated-orcid":false,"given":"Martin","family":"Lindberg-Larsen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Centre for Prosthetic Infections, Odense University Hospital, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2806-4739","authenticated-orcid":false,"given":"Sophie","family":"Reissier","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, CHU Rennes University Hospital, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0240-0879","authenticated-orcid":false,"given":"Nicol\u00f2","family":"Rossi","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery, Ospedale Gugliemo da Saliceto, Piacenza, Italia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4935-8754","authenticated-orcid":false,"given":"Maria","family":"Dolores Del Toro Lopez","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1483-4255","authenticated-orcid":false,"given":"Micael","family":"Widerstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2885-1208","authenticated-orcid":false,"given":"Marta","family":"Fernandez Sampedro","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Hospital Universitario Marques de Valdecilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6334-0967","authenticated-orcid":false,"given":"Ewout S.","family":"Veltman","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, University Medical Center Rotterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Petersdorf","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Virology & Hygiene, Helios Universit\u00e4tsklinikum Universit\u00e4t Witten\/ HerdeckeBochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8587-4433","authenticated-orcid":false,"given":"Holger","family":"Rohde","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, Universit\u00e4ts-Krankenhaus Eppendorf, Hamburg, 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