{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T02:58:10Z","timestamp":1785466690842,"version":"3.56.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Legg-Calv\u00e9-Perthes disease (LCPD) is idiopathic osteonecrosis of the femoral head. The effects of proximal femoral varus osteotomy (PFVO) on femoral head revascularization are unknown. We evaluated whether patients with early-stage LCPD treated with PFVO had a higher revascularization rate than those receiving nonoperative treatment with serial perfusion magnetic resonance imaging (pMRI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Forty-nine patients (49 hips) in early-stage LCPD with \u22652 pMRIs treated nonoperatively (n = 22) or with PFVO (n = 27) were retrospectively analyzed. The mean age of diagnosis was 8.2 \u00b1 1.7 years (range: 5.3-12.2), median pMRI of 3 (IQR:2-4; range: 2-6), and Waldenstr\u00f6m stage I (n = 37) or IIa (n = 12). The revascularization rate (%\/month) was assessed in 4-month intervals. Time to Waldenstr\u00f6m stage IIIb and full weight-bearing status (FWB) were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Baseline characteristics (age, initial perfusion, Waldenstr\u00f6m stage) were similar between groups. Perfusion was higher in the PFVO group at 4 to 8 (56 \u00b1 20 vs. 80 \u00b1 12%, p = 0.001) and 12 to 16 months (68 \u00b1 25 vs. 91 \u00b1 7%, p = 0.02) follow-ups. The PFVO group had significantly higher revascularization rates at 3 intervals: 4 to 8 (4.2 \u00b1 2.7 vs. 7.0 \u00b1 2.1%\/month, p = 0.006), 8 to 12 (3.4 \u00b1 1.7 vs. 6.1 \u00b1 1.5%\/month, p = 0.004), and 12 to 16 months (2.5 \u00b1 1.3 vs. 4.9 \u00b1 1.1%\/month, p = 0.002). The PFVO group had a shorter time to Waldenstr\u00f6m stage IIIb (22.7 \u00b1 8.7 vs. 17.1 \u00b1 6.9 months, p = 0.02) and was associated with earlier FWB (18.8 \u00b1 6.5 vs. 13.1 \u00b1 4.7 months, p = 0.008).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The PFVO group had faster revascularization and a shorter time to the late-reossification stage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance:<\/jats:title>\n                    <jats:p>This study is the first to investigate the effects of PFVO on revascularization rate using serial pMRI. These findings provide novel insight into the biologic effect of PFVO on femoral head revascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      <jats:underline>Level IV<\/jats:underline>\n                      , therapeutic. See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.oa.26.00164","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T21:01:16Z","timestamp":1784322076000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Proximal Femoral Varus Osteotomy Performed in the Early Stage of Legg-Calv\u00e9-Perthes Disease Increases Femoral Head Revascularization"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9079-6568","authenticated-orcid":false,"given":"Joonoh","family":"Lee","sequence":"first","affiliation":[{"name":"University of Texas Southwestern Medical Center, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7331-7654","authenticated-orcid":false,"given":"Ahan","family":"Mistry","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Center of Excellence in Hip, Scottish Rite for Children, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0330-4777","authenticated-orcid":false,"given":"Harry K.W.","family":"Kim","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center, Dallas, Texas"},{"name":"Department of Orthopaedic Surgery, Center of Excellence in Hip, Scottish Rite for Children, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7]]},"reference":[{"issue":"1-4","key":"R1-20260731","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/17453673408991314","article-title":"The first stages of Coxa Plana","volume":"5","author":"Waldenstrom","year":"1934","journal-title":"Acta Orthop Scand"},{"issue":"8","key":"R2-20260731","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/s00247-002-0732-5","article-title":"Femoral head vascularisation in Legg-Calv\u00e9-Perthes disease: comparison of dynamic gadolinium-enhanced subtraction MRI with bone scintigraphy","volume":"32","author":"Lamer","year":"2002","journal-title":"Pediatr Radiol"},{"issue":"3","key":"R3-20260731","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1034\/j.1600-0455.2002.430317.x","article-title":"MR signal intensity characteristics in Legg-Calv\u00e9-Perthes disease. 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