{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T02:16:16Z","timestamp":1787969776913,"version":"build-2784847793"},"reference-count":85,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Rev"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:p>\n                    <jats:list list-type=\"plain\">\n                      <jats:list-item>\n                        <jats:p>* Symptomatic spinal metastasis is increasingly more common in patients with cancer as therapy for the primary disease advances and patients\u2019 outcomes and life expectancy improve.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>* Treatment for this condition is almost always palliative, with the goals being prevention and treatment of spine-related events, such as pain, vertebral fracture, and spinal cord compression.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>* The main approaches for the management of spinal metastasis are chemotherapy with targeted agents for overall disease control and radiation therapy and surgical procedures to treat spine-related events and to improve local control.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>* Optimal management of patients with spinal metastasis is a challenge that requires a multidisciplinary approach. Treatment must be selected on an individual basis after careful evaluation of the tumor, the patient\u2019s performance status, and the characteristics of the spinal lesion by the respective specialists.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>* Long-term palliation and local control are now feasible with newer techniques\u2014a minimally invasive surgical procedure, a separation surgical procedure, stereotactic body radiation therapy, and radiosurgery\u2014that have changed the treatment paradigms.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.2106\/jbjs.rvw.17.00118","type":"journal-article","created":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T17:54:16Z","timestamp":1526406856000},"page":"e6-e6","source":"Crossref","is-referenced-by-count":9,"title":["Team Approach: Metastatic Disease of the 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