{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:47:25Z","timestamp":1787755645841,"version":"build-2784847793"},"reference-count":189,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    <jats:list list-type=\"plain\">\n                      <jats:list-item>\n                        <jats:p>\u00bb New knowledge about the molecular biology of fracture-healing provides opportunities for intervention and reduction of risk for specific phases that are affected by disease and medications.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\u00bb Modifiable and nonmodifiable risk factors can prolong healing, and the informed clinician should optimize each patient to provide the best chance for union.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\u00bb Techniques to monitor progression of fracture-healing have not changed substantially over time; new objective modalities are needed.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.2106\/jbjs.rvw.19.00221","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T11:00:29Z","timestamp":1597316429000},"page":"e19.00221","source":"Crossref","is-referenced-by-count":27,"title":["The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union"],"prefix":"10.2106","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3421-5363","authenticated-orcid":false,"given":"Justin E.","family":"Hellwinkel","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, New York Presbyterian 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