{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:39:38Z","timestamp":1788575978829,"version":"build-2803163510"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    <jats:list list-type=\"plain\">\n                      <jats:list-item>\n                        <jats:p>\u00bb Skin adhesives are increasingly used in orthopaedic surgery because they provide secure incision closure, limit postoperative drainage, support wound integrity, and may reduce operative time. However, allergic contact dermatitis (ACD) remains an important consideration with their use. ACD is a hypersensitivity skin reaction seen in some patients exposed to surgical adhesives, particularly the 2-octyl cyanoacrylate ingredient. It can be difficult to distinguish ACD from cellulitis or surgical site infections due to overlapping clinical features. Timely recognition is critical, as early management can minimize wound complications and optimize outcomes. Management options include removal of the adhesive, topical corticosteroids, oral antihistamines, and antibiotics with concomitant infection. This review highlights the role of surgical adhesives across several orthopaedic surgery subspecialties, emphasizing the incidence, recognition, and management of surgical adhesive\u2013related ACD.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.2106\/jbjs.rvw.25.00178","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T19:00:28Z","timestamp":1765911628000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Hypersensitivity Reactions to Liquid Skin Adhesives in Orthopaedic Surgery"],"prefix":"10.2106","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2665-3096","authenticated-orcid":false,"given":"Matthew T.","family":"Geiselmann","sequence":"first","affiliation":[{"name":"Northwell, New Hyde Park, New York"},{"name":"Department of Orthopaedic Surgery, Northwell Health Huntington Hospital, Huntington, New York"},{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1071-4038","authenticated-orcid":false,"given":"George","family":"Economou","sequence":"additional","affiliation":[{"name":"Northwell, New Hyde Park, New York"},{"name":"Department of Orthopaedic Surgery, Northwell Health Huntington Hospital, Huntington, New York"},{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2773-314X","authenticated-orcid":false,"given":"Constantina","family":"Economou","sequence":"additional","affiliation":[{"name":"New York Institute of Technology, College of Osteopathic Medicine, Old Westbury, New 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Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York"},{"name":"Orlin and Cohen Orthopedic Group, Lynbrook, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12]]},"reference":[{"issue":"10","key":"r1-20251216","first-page":"476","article-title":"Dermabond efficacy in total joint arthroplasty wounds","volume":"39","author":"Miller","year":"2010","journal-title":"Am J Orthop (Belle Mead NJ)"},{"issue":"2","key":"r2-20251216","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/DER.0000000000000163","article-title":"Severe allergic contact dermatitis to Dermabond Prineo, a topical skin adhesive of 2-octyl cyanoacrylate increasingly used in surgeries to close wounds","volume":"27","author":"Davis","year":"2016","journal-title":"Dermatitis"},{"issue":"1","key":"r3-20251216","doi-asserted-by":"crossref","first-page":"e0306","DOI":"10.2106\/JBJS.CC.18.00306","article-title":"Severe wound 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