{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T14:57:37Z","timestamp":1791730657032,"version":"4.3.4"},"reference-count":22,"publisher":"Zoological Society of Japan","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zoological Science"],"published-print":{"date-parts":[[2024,9,4]]},"abstract":"<jats:p>Yawning is a stereotyped behavior widely observed in vertebrates, serving as an adaptation to the environment. Previous research has highlighted the correlations between yawning and physiological arousal or temperature regulation. However, the majority of those studies have primarily focused on endothermic animals. Thus far, the function of yawning in ectothermic animals remains unclear. In this study, we observed the behavior of leopard geckos, Eublepharis macularius, ectothermic reptiles, over a period of 3 days under constant ambient temperatures of 25\u00b0C, 30\u00b0C, or 35\u00b0C. By investigating the relationship between temperature, spontaneous yawning, and activity levels, we found that yawning frequency is affected by ambient temperature, and also observed a significant increase in post-yawning activity particularly under the 30\u00b0C and 35\u00b0C conditions. Furthermore, a near 24-hour periodicity in yawning was detected under all temperature conditions. These results align with previous studies conducted on endothermic animals, suggesting the conservation of primitive functions of yawning across vertebrate species.<\/jats:p>","DOI":"10.2108\/zs230123","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T01:17:05Z","timestamp":1725326225000},"page":"25-30","source":"Crossref","is-referenced-by-count":7,"title":["Yawning and Its Temperature-Dependent Modulation in Leopard Geckos"],"prefix":"10.2108","volume":"42","author":[{"given":"Koki T.","family":"Kotake","sequence":"first","affiliation":[{"name":"Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho T.","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasutaka","family":"Mukai","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwen","family":"Zhou","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Norimoto","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"848","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"R Baenninger, S Binkley, M Baenninger,  \"Physiol Behav.\"  59, \"Field observations of yawning and activity in humans.\" 421 (1996)","DOI":"10.1016\/0031-9384(95)02014-4"},{"key":"2","unstructured":"KA Bakkegard,  \"Herpetol Rev.\"  48, \"Yawning by Red Hills salamanders (Phaeognathus hubrichti) at their burrow entrance.\" 32 (2017)"},{"key":"3","doi-asserted-by":"crossref","unstructured":"J Barbizet,  \"J Neurol Neurosur Psychiatry.\"  21, \"Yawning.\" 203 (1958)","DOI":"10.1136\/jnnp.21.3.203"},{"key":"4","doi-asserted-by":"crossref","unstructured":"MA Barbour  and RW Clark  \"Ethology.\"  118, \"Diel cycles in chemosensory behaviors of free-ranging rattlesnakes lying in wait for prey.\" 480 (2012)","DOI":"10.1111\/j.1439-0310.2012.02035.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"BL Deputte,  \"Ethology.\"  98, \"Ethological study of yawning in primates. I. Quantitative analysis and study of causation in two species of old world monkeys (Cercocebus albigena and Macaca fascicularis).\" 221 (1994)","DOI":"10.1111\/j.1439-0310.1994.tb01073.x"},{"key":"6","doi-asserted-by":"crossref","unstructured":"AC Gallup, ML Miller, AB Clark,  \"Anim Behav.\"  77, \"Yawning and thermoregulation in budgerigars, Melopsittacus undulatus.\" 109 (2009)","DOI":"10.1016\/j.anbehav.2008.09.014"},{"key":"7","doi-asserted-by":"crossref","unstructured":"AC Gallup, RR Miller, AB Clark,  \"Ethology.\"  116, \"Changes in ambient temperature trigger yawing but not stretching in rats.\" 1 (2010)","DOI":"10.1111\/j.1439-0310.2010.01854.x"},{"key":"8","doi-asserted-by":"crossref","unstructured":"AC Gallup, AM Church, AJ Pelegrino,  \"Biol Lett.\"  12, \"Yawn duration predicts brain weight and cortical neuron number in mammals.\" 20160545 (2016)","DOI":"10.1098\/rsbl.2016.0545"},{"key":"9","doi-asserted-by":"crossref","unstructured":"BM Graves  and D Duvall  \"J Exp Zool.\"  227, \"Occurrence and function of prairie rattlesnake mouth gaping in a non-feeding context.\" 471 (1983)","DOI":"10.1002\/jez.1402270316"},{"key":"10","doi-asserted-by":"crossref","unstructured":"SE Lazic,  \"BMC Neurosci.\"  11, \"The problem of pseudoreplication in neuroscientific studies: is it affecting your analysis?\" 5 (2010)","DOI":"10.1186\/1471-2202-11-5"},{"key":"11","doi-asserted-by":"crossref","unstructured":"JJM Massen, K Dusch, OT Eldakar, et al.  \"Physiol Behav.\"  130, \"A thermal window for yawning in humans: yawning as a brain cooling mechanism.\" 145 (2014)","DOI":"10.1016\/j.physbeh.2014.03.032"},{"key":"12","doi-asserted-by":"crossref","unstructured":"JJM Massen, M Hartlieb, JS Martin, et al.  \"Commun Biol.\"  4, \"Brain size and neuron numbers drive differences in yawn duration across mammals and birds.\" 503 (2021)","DOI":"10.1038\/s42003-021-02019-y"},{"key":"13","doi-asserted-by":"crossref","unstructured":"A Mathis, P Mamidanna, KM Cury, et al.  \"Nat Neurosci.\"  21, \"DeepLabCut: markerless pose estimation of user-defined body parts with deep learning.\" 1281 (2018)","DOI":"10.1038\/s41593-018-0209-y"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Y Mukai, T Okubo, M Lazarus, et al.  \"J Neurosci.\"  43, \"Prostaglandin E2 induces long-lasting inhibition of noradrenergic neurons in the locus coeruleus and moderates the behavioral response to stressors.\" 7982 (2023)","DOI":"10.1523\/JNEUROSCI.0353-23.2023"},{"key":"15","doi-asserted-by":"crossref","unstructured":"E Palagi, F Guill\u00e9n-Salazar, C Llamazares-Mart\u00edn,  \"Sci Rep.\"  9, \"Spontaneous yawning and its potential functions in South American Sea Lions (Otaria flavescens).\" 17226 (2019)","DOI":"10.1038\/s41598-019-53613-4"},{"key":"16","doi-asserted-by":"crossref","unstructured":"RR Provine,  \"Ethology.\"  72, \"Yawning as a stereotyped action pattern and releasing stimulus.\" 109 (1986)","DOI":"10.1111\/j.1439-0310.1986.tb00611.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"S-J Vick  and A Paukner  \"Am J Primatol.\"  72, \"Variation and context of yawns in captive chimpanzees (Pan troglodytes).\" 262 (2010)","DOI":"10.1002\/ajp.20781"},{"key":"18","doi-asserted-by":"crossref","unstructured":"MD Whitford, GA Freymiller, TE Higham, et al.  \"J Exp Biol.\"  223, \"The effects of temperature on the defensive strikes of rattlesnakes.\" jeb223859 (2020)","DOI":"10.1242\/jeb.223859"},{"key":"19","doi-asserted-by":"crossref","unstructured":"H Yamada  and S Wada  \"J Ethol.\"  41, \"Fish yawn: the state-change hypothesis in juvenile white-spotted char Salvelinus leucomaenis.\" 111 (2023)","DOI":"10.1007\/s10164-023-00777-2"},{"key":"20","doi-asserted-by":"crossref","unstructured":"ST Yamaguchi, S Hatori, KT Kotake, et al.  \"PNAS Nexus.\"  3, \"Circadian control of sleep-related neuronal activity in lizards.\" pgad481 (2024)","DOI":"10.1093\/pnasnexus\/pgad481"},{"key":"21","doi-asserted-by":"crossref","unstructured":"Z Yu, M Guindani, SF Grieco, et al.  \"Neuron.\"  110, \"Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research.\" 21 (2022)","DOI":"10.1016\/j.neuron.2021.10.030"},{"key":"22","doi-asserted-by":"crossref","unstructured":"I Zilli, F Giganti, V Uga,  \"J Sleep Res.\"  17, \"Yawning and subjective sleepiness in the elderly.\" 303 (2008)","DOI":"10.1111\/j.1365-2869.2008.00666.x"}],"container-title":["Zoological Science"],"original-title":[],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:18:20Z","timestamp":1791245900000},"score":1,"resource":{"primary":{"URL":"https:\/\/bioone.org\/journals\/zoological-science\/volume-42\/issue-1\/zs230123\/Yawning-and-Its-Temperature-Dependent-Modulation-in-Leopard-Geckos\/10.2108\/zs230123.full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,4]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,2,1]]}},"URL":"https:\/\/doi.org\/10.2108\/zs230123","relation":{},"ISSN":["0289-0003","2212-3830"],"issn-type":[{"value":"0289-0003","type":"print"},{"value":"2212-3830","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,4]]}}}