{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T03:44:56Z","timestamp":1768794296040,"version":"3.49.0"},"reference-count":31,"publisher":"Instituto Nacional de Salud Publica","issue":"6, nov-dic","license":[{"start":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T00:00:00Z","timestamp":1544659200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/legalcode"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Salud Publica Mex"],"abstract":"<jats:p>Objective. To estimate the burden of genital warts (GW) in Mexico. Materials and methods. We estimated the annual incidence of GW based on data reported by specialist physicians. We also assessed GW treatment practices, the average cost of treatment, and the psychosocial burden of GW among patients. Results. The annual incidence of GW in Mexico was estimated to be 547 200 cases. Treatment procedures vary by specialist and patient gender. The estimated annual cost was $195 million USD. The psychosocial impact of GW was slightly greater in males than females. Conclusions. This is the first evaluation of the burden of GW in Mexico. Our data suggest that GW are common, with significant health-related costs and psychosocial impact.<\/jats:p>","DOI":"10.21149\/10008","type":"journal-article","created":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T00:50:59Z","timestamp":1544748659000},"page":"624","source":"Crossref","is-referenced-by-count":15,"title":["Incidence, psychosocial burden, and economic impact of genital warts in Mexico"],"prefix":"10.21149","volume":"60","author":[{"given":"Marta","family":"Domenech-Vi\u00f1olas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leith","family":"Le\u00f3n-Maldonado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2586-4396","authenticated-orcid":false,"given":"Paula","family":"Ram\u00edrez-Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne N","family":"Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Granados-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgar","family":"Corona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Lazcano-Ponce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Salmer\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8786","published-online":{"date-parts":[[2018,12,13]]},"reference":[{"issue":"10","key":"ref0","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1128\/JCM.37.10.3316-3322.1999","article-title":"Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients.","volume":"37","author":"Brown","year":"1999","unstructured":"1. Brown DR, Schroeder JM, Bryan JT, Stoler MH, Fife KH. Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients. J Clin Microbiol. 1999;37(10):3316-22.","journal-title":"J Clin Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Hernandez-Suarez G, Pineros M, Vargas JC, Orjuela L, Hernandez F, Peroza C, et al. Human papillomavirus genotypes in genital warts in Latin America: a cross-sectional study in Bogota, Colombia. Int J STD AIDS. 2013;24(7):567-72. https:\/\/doi.org\/10.1177\/0956462412474538","DOI":"10.1177\/0956462412474538"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Forman D, de Martel C, Lacey CJ, Soerjomataram I, Lortet-Tieulent J, Bruni L, et al. Global burden of human papillomavirus and related diseases. Vaccine. 2012;30(Suppl 5):F12-23. https:\/\/doi.org\/10.1016\/j.vaccine.2012.07.055","DOI":"10.1016\/j.vaccine.2012.07.055"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"2. Lacey CJ, Lowndes CM, Shah KV. Chapter 4: Burden and management of non-cancerous HPV-related conditions: HPV-6\/11 disease. Vaccine. 2006;24(Suppl 3):S3\/35-41.","DOI":"10.1016\/j.vaccine.2006.06.015"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Parkin DM, Louie KS, Clifford G. Burden and trends of type-specific human papillomavirus infections and related diseases in the Asia Pacific region. Vaccine. 2008;26(Suppl 12):M1-16. https:\/\/doi.org\/10.1016\/j.vaccine.2008.05.010","DOI":"10.1016\/j.vaccine.2008.05.010"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Pr\u00e9aud E, Largeron N. Economic burden of non-cervical cancers attributable to human papillomavirus: a European scoping review. J Med Econ. 2013;16(6):763-76. https:\/\/doi.org\/10.3111\/13696998.2013.793691","DOI":"10.3111\/13696998.2013.793691"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. Dominiak-Felden G, Cohet C, Atrux-Tallau S, Gilet H, Tristram A, Fiander A. Impact of human papillomavirus-related genital diseases on quality of life and psychosocial wellbeing: results of an observational, healthrelated quality of life study in the UK. BMC Public Health. 2013;13:1065. https:\/\/doi.org\/10.1186\/1471-2458-13-1065","DOI":"10.1186\/1471-2458-13-1065"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8. Coles VA, Chapman R, Lanitis T, Carroll SM. The costs of managing genital warts in the UK by devolved nation: England, Scotland, Wales and Northern Ireland. Int J STD AIDS. 2016;27(1):51-7. https:\/\/doi.org\/10.1177\/0956462415573121","DOI":"10.1177\/0956462415573121"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"9. Brotherton JM, Heywood A, Heley S. The incidence of genital warts in Australian women prior to the national vaccination program. Sex Health. 2009;6(3):178-84. https:\/\/doi.org\/10.1071\/SH08079","DOI":"10.1071\/SH08079"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. Park IU, Introcaso C, Dunne EF. Human Papillomavirus and Genital Warts: A Review of the Evidence for the 2015 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines. Clin Infect Dis. 2015;61 Suppl 8:S849-55. https:\/\/doi.org\/10.1093\/cid\/civ813","DOI":"10.1093\/cid\/civ813"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. Scarbrough-Lefebvre CD, Van Kriekinge G, Gon\u00e7alves MA, de Sanjose S. Appraisal of the burden of genital warts from a healthcare and individual patient perspective. Public Health. 2011;125(7):464-75. https:\/\/doi.org\/10.1016\/j.puhe.2011.01.016","DOI":"10.1016\/j.puhe.2011.01.016"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. Parkin DM, Almonte M, Bruni L, Clifford G, Curado MP, Pi-eros M. Burden and trends of type-specific human papillomavirus infections and related diseases in Latin America and Caribbean region. Vaccine. 2008;26 (Suppl 11):L1-15. https:\/\/doi.org\/10.1016\/j.vaccine.2008.05.043","DOI":"10.1016\/j.vaccine.2008.05.043"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Tejada RA, Vargas KG, Benites-Zapata V, Mezones-Holgu\u00edn E, Bola-osD\u00edaz R, Hernandez AV. Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis. Salud Publica Mex. 2017;59(1):84-94. https:\/\/doi.org\/10.21149\/7824","DOI":"10.21149\/7824"},{"issue":"5","key":"ref13","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1136\/sti.73.5.365","article-title":"Epidemiology of genital warts in England and Wales: 1971 to 1994","volume":"73","author":"Simms","year":"1997","unstructured":"14. Simms I, Fairley CK. Epidemiology of genital warts in England and Wales: 1971 to 1994. Genitourin Med. 1997;73(5):365-7.","journal-title":"Genitourin Med"},{"issue":"5","key":"ref14","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1038\/bjc.1983.243","article-title":"Genital warts and cervical neoplasia: an epidemiological study","volume":"48","author":"Franceschi","year":"1983","unstructured":"15. Franceschi S, Doll R, Gallwey J, La Vecchia C, Peto R, Spriggs AI. Genital warts and cervical neoplasia: an epidemiological study. Br J Cancer. 1983;48(5):621-8.","journal-title":"Br J Cancer"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Canvin M, Sinka K, Hughes G, Mesher D. Decline in genital warts diagnoses among young women and young men since the introduction of the bivalent HPV (16\/18) vaccination programme in England: an ecological analysis. Sex Transm Infect. 2017;93(2):125-8. https:\/\/doi.org\/10.1136\/sextrans-2016-052626","DOI":"10.1136\/sextrans-2016-052626"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17. Patel H, Wagner M, Singhal P, Kothari S. Systematic review of the incidence and prevalence of genital warts. BMC Infect Dis. 2013;13:39. https:\/\/doi.org\/10.1186\/1471-2334-13-39","DOI":"10.1186\/1471-2334-13-39"},{"issue":"6","key":"ref17","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1002\/ijc.23260","article-title":"Safety, immunogenicity, and efficacy of quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like-particle vaccine in Latin American women","volume":"122","author":"Perez","year":"2008","unstructured":"18. Perez G, Lazcano-Ponce E, Hernandez-Avila M, Garc\u00eda PJ, Mu-oz N, Villa LL, et al. Safety, immunogenicity, and efficacy of quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like-particle vaccine in Latin American women. Int J Cancer. 2008;122(6):1311-8.","journal-title":"Int J Cancer"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19. Anic GM, Lee JH, Stockwell H, Rollison DE, Wu Y, Papenfuss MR, et al. Incidence and human papillomavirus (HPV) type distribution of genital warts in a multinational cohort of men: the HPV in men study. J Infect Dis. 2011;204(12):1886-92. https:\/\/doi.org\/10.1093\/infdis\/jir652","DOI":"10.1093\/infdis\/jir652"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20. Lacey CJN. Genital warts and mucosal papillomavirus disease. Med (United Kingdom). 2014;42(7):349-53. https:\/\/doi.org\/10.1016\/j.mpmed.2014.04.012","DOI":"10.1016\/j.mpmed.2014.04.012"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. Pirotta M, Stein AN, Conway EL, Harrison C, Britt H, Garland S. Genital warts incidence and healthcare resource utilisation in Australia. Sex Transm Infect. 2010;86(3):181-6. https:\/\/doi.org\/10.1136\/sti.2009.040188","DOI":"10.1136\/sti.2009.040188"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22. Raymakers AJ, Sadatsafavi M, Marra F, Marra CA. Economic and humanistic burden of external genital warts. Pharmacoeconomics. 2012;30(1):1-16. https:\/\/doi.org\/10.2165\/11591170-000000000-00000","DOI":"10.2165\/11591170-000000000-00000"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23. Castellsagu\u00e9 X, Cohet C, Puig-Tintor\u00e9 LM, Acebes LO, Salinas J, San Martin M, et al. Epidemiology and cost of treatment of genital warts in Spain. Eur J Public Health. 2009;19(1):106-10. https:\/\/doi.org\/10.1093\/eurpub\/ckn127","DOI":"10.1093\/eurpub\/ckn127"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"24. Scarbrough-Lefebvre CD, Van Kriekinge G, Gon\u00e7alves MA, de Sanjose S. Appraisal of the burden of genital warts from a healthcare and individual patient perspective. Public Health. 2011;125(7):464-75. https:\/\/doi.org\/10.1016\/j.puhe.2011.01.016","DOI":"10.1016\/j.puhe.2011.01.016"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"25. Mast TC, Zhu X, Demuro-Mercon C, Cummings HW, Sings HL, Ferris DG. Development and psychometric properties of the HPV Impact Profile (HIP) to assess the psychosocial burden of HPV. Curr Med Res Opin. 2009;25(11):2609-19. https:\/\/doi.org\/10.1185\/03007990903238786","DOI":"10.1185\/03007990903238786"},{"issue":"3","key":"ref25","first-page":"257","article-title":"Validation and clinical use of the CECA, a disease-specific quality of life questionnaire for patients with anogenital condylomata acuminata.","volume":"88","author":"Vilata","year":"2008","unstructured":"26. Vilata JJ, Varela JA, Olmos L, Colombo JA, Llorens MA, de los Terreros MS, et al. ECCAVIM Study Group. Validation and clinical use of the CECA, a disease-specific quality of life questionnaire for patients with anogenital condylomata acuminata. Acta Derm Venereol. 2008;88(3):257-62. https:\/\/doi.org\/10.2340\/00015555-0422","journal-title":"Acta Derm Venereol","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5555","issn-type":"print"},{"issue":"5","key":"ref26","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1177\/0193841X09340214","article-title":"A comparison of web-based and paper-based survey methods: testing assumptions of survey mode and response cost.","volume":"33","author":"Greenlaw","year":"2009","unstructured":"27. Greenlaw C, Brown-Welty S. A comparison of web-based and paper-based survey methods: testing assumptions of survey mode and response cost. Eval Rev. 2009;33(5):464-80. https:\/\/doi.org\/10.1177\/0193841X09340214","journal-title":"Eval Rev","ISSN":"https:\/\/id.crossref.org\/issn\/0193-841X","issn-type":"print"},{"issue":"1","key":"ref27","first-page":"33","article-title":"A new approach to estimate Genital Warts incidence and prevalence in the Italian general female population.","volume":"20","author":"Vittori","year":"2008","unstructured":"28. Vittori G, Matteelli A, Boselli F, Naldi L, Gialloreti LE. A new approach to estimate Genital Warts incidence and prevalence in the Italian general female population. Ital J Gynaecol Obstet. 2008;20(1):33-42.","journal-title":"Int J Gynaecol Obstet","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7292","issn-type":"print"},{"key":"ref28","volume-title":"VillalpandoHern\u00e1ndez S Franco A Cuevas-Nasu L et al Encuesta Nacional de Salud y Nutrici\u00f3n 2012 Resultados Nacionales","author":"Guti\u00e9rrez","year":"2012","unstructured":"29. Guti\u00e9rrez JP, Rivera-Dommarco J, Shamah-Levy T, VillalpandoHern\u00e1ndez S, Franco A, Cuevas-Nasu L. et al. Encuesta Nacional de Salud y Nutrici\u00f3n 2012. Resultados Nacionales. Cuernavaca, M\u00e9xico: Instituto Nacional de Salud P\u00fablica, 2012."},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"30. Garland SM, Steben M, Sings HL, James M, Lu S, Railkar R, et al. Natural history of genital warts: analysis of the placebo arm of 2 randomized phase III trials of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine. J Infect Dis. 2009;199(6):805-14. https:\/\/doi.org\/10.1086\/597071","DOI":"10.1086\/597071"},{"issue":"9","key":"ref30","doi-asserted-by":"publisher","first-page":"e005687","DOI":"10.1136\/bmjopen-2014-005687","article-title":"A prospective cohort study characterising the role of anogenital warts in HIV acquisition among men who have sex with men: a study protocol.","volume":"4","author":"Brown","year":"2014","unstructured":"31. Brown B, Davtyan M, Leon SR, Sanchez H, Calvo G, Klausner JD, Galea J. A prospective cohort study characterising the role of anogenital warts in HIV acquisition among men who have sex with men: a study protocol. BMJ Open. 2014;4(9):e005687.","journal-title":"BMJ Open","ISSN":"https:\/\/id.crossref.org\/issn\/2044-6055","issn-type":"print"}],"container-title":["Salud P\u00fablica de M\u00e9xico"],"original-title":[],"link":[{"URL":"http:\/\/www.saludpublica.mx\/index.php\/spm\/article\/viewFile\/10008\/11678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.saludpublica.mx\/index.php\/spm\/article\/viewFile\/10008\/11678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T15:46:42Z","timestamp":1605628002000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.saludpublica.mx\/index.php\/spm\/article\/view\/10008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,13]]},"references-count":31,"journal-issue":{"issue":"6, nov-dic","published-online":{"date-parts":[[2018,12,13]]}},"URL":"https:\/\/doi.org\/10.21149\/10008","relation":{},"ISSN":["1606-7916","0036-3634"],"issn-type":[{"value":"1606-7916","type":"electronic"},{"value":"0036-3634","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12,13]]}}}