{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:27:36Z","timestamp":1764174456560},"reference-count":21,"publisher":"Instituto Nacional de Salud Publica","issue":"2,mar-abr","license":[{"start":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T00:00:00Z","timestamp":1521763200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/legalcode"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Salud Publica Mex"],"abstract":"<jats:p>Objetivo. Describir la tendencia de cepas multidrogorre\u00adsistentes (MDR) aisladas en hemocultivos de pacientes con c\u00e1ncer durante el periodo de 2005 a 2015. Material y m\u00e9todos. An\u00e1lisis retrospectivo en el que se procesaron 33 127 hemocultivos. La identificaci\u00f3n y la sensibilidad antimicro\u00adbianas se realizaron a trav\u00e9s de m\u00e9todos automatizados WaLK away (Siemens Laboratory Diagnostics) y BD Phoenix (Becton, Dickinson and Company). Se determinaron cepas resistentes de acuerdo con la concentraci\u00f3n m\u00ednima inhibitoria, seg\u00fan los pa\u00adr\u00e1metros del Clinical and Laboratory Standards Institute (CLSI). Resultados. 5 604 (16.9%) aislamientos fueron positivos, con 6 397 aislamientos, 3 732 (58.4%) bacilos gramnegativos, 2 355 (36.9%) cocos grampositivos, 179 (2.7%) levaduras y 126 (1.9%) bacilos grampositivos. Escherichia coli (n=1 591, 24.5%) fue la bacteria m\u00e1s frecuente, 652 (41%) productoras de beta-lactamasas de espectro-extendido (BLEE); Enterococ\u00adcus faecium 143 (2.1%), 45 (31.5%) resistente a vancomicina; Staphylococcus aureus 571 (8.7%), 121 (21.2%) resistentes a meticilina (SARM); Klebsiella pneumoniae 367 (5.6%), 41 (11.2%) BLEE, Acinetobacter baumannii 96 (1.4%), 23 (24%) MDR; Pseudomonas aeruginosa 384 (5.6%), 43 (11.2%) MDR. Las cepas MDR se aislaron m\u00e1s frecuentemente en pacientes con neoplasias hematol\u00f3gicas en comparaci\u00f3n con tumores s\u00f3lidos; SARM (RM=4.48, IC95% 2.9-6.8); E. coli BLEE (RM=1.3, IC95% 1.10-1.65) y A. baumannii-MDR (RM=3.2, IC95% 1.2-8.3). Conclusiones. Se observ\u00f3 un aislamiento significativamente mayor de cepas E-ESKAPE MDR en pacientes con neoplasias hematol\u00f3gicas.<\/jats:p>","DOI":"10.21149\/8767","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T01:36:26Z","timestamp":1521855386000},"page":"151","source":"Crossref","is-referenced-by-count":5,"title":["Cepas E-ESKAPE multidrogorresistentes aisladas en hemocultivos de pacientes con c\u00e1ncer"],"prefix":"10.21149","volume":"60","author":[{"given":"Consuelo","family":"Vel\u00e1zquez-Acosta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Cornejo-Ju\u00e1rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Volkow-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8786","published-online":{"date-parts":[[2018,3,23]]},"reference":[{"key":"ref0","unstructured":"1. 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