{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:17:00Z","timestamp":1761920220423},"reference-count":0,"publisher":"Pomorski Uniwersytet Medyczny w Szczecinie","issue":"2","license":[{"start":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T00:00:00Z","timestamp":1481155200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/pl\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pomeranian J Life Sci"],"abstract":"<jats:p>Wst\u0119p:Niealkoholowa st\u0142uszczeniowa choroba w\u0105troby (NAFLD) jest zwi\u0105zana z wysokim ryzykiem zaburze\u0144 metabolicznych (zesp\u00f3\u0142 metaboliczny, cukrzyca typu 2) oraz choroby wie\u0144cowej.Materia\u0142y i metody: Grup\u0119 badan\u0105 stanowi\u0142o 108 os\u00f3b doros\u0142ych rasy kaukaskiej (39 kobiet i 69 m\u0119\u017cczyzn) w wieku 20\u201377 lat z rozpoznan\u0105 NAFLD. Podstaw\u0105 diagnozy by\u0142o dok\u0142adne badanie USG w\u0105troby oraz analiza parametr\u00f3w w\u0105trobowych: aminotransferazy alaninowej i aminotransferazy asparaginianowej w surowicy. Wszystkie badania przeprowadzono podczas pierwszej i ostatniej wizyty pacjent\u00f3w w plac\u00f3wce badawczej (po 6 miesi\u0105cach od interwencji dietetycznej). Dokonywano tak\u017ce pomiar\u00f3w antropometrycznych (wska\u017anik masy cia\u0142a \u2013 BMI, obw\u00f3d pasa \u2013 WC, wska\u017anik talia\u2013biodra \u2013 WHR, wska\u017a- nik talia\u2013wzrost \u2013 WHtR, wska\u017anik sto\u017ckowato\u015bci \u2013 C -Index) w odniesieniu do metabolicznych czynnik\u00f3w ryzyka choroby niedokrwiennej serca (podwy\u017cszone st\u0119\u017cenie w surowicy: triacylogliceroli, cholesterolu lipoprotein niskiej g\u0119sto\u015bci, cholesterolu ca\u0142kowitego, glukozy oraz obni\u017cone st\u0119\u017cenie cholesterolu lipoprotein wysokiej g\u0119sto\u015bci).Wyniki: Zar\u00f3wno w grupie kobiet, jak i m\u0119\u017cczyzn wykazano istotn\u0105 statystycznie redukcj\u0119 warto\u015bci parametr\u00f3w takich jak: masa cia\u0142a, BMI, WC, WHR, WHtR i C -Index (p &lt; 0,05), co mia\u0142o wp\u0142yw na popraw\u0119 st\u0119\u017cenia triacylogliceroli w surowicy u obu p\u0142ci (p &lt; 0,05). Wska\u017aniki identy\u03d0ikuj\u0105ce oty\u0142o\u015b\u0107 brzuszn\u0105 (WC, WHR, WHtR, C -Index) korelowa\u0142y istotnie z warto\u015bci\u0105 glikemii (p &lt; 0,05) zar\u00f3wno przed interwencj\u0105 dietetyczn\u0105, jak i po niej oraz ze st\u0119\u017ceniem lipid\u00f3w w surowicy przed interwencj\u0105 lub po (p &lt; 0,05) u obu p\u0142ci.Wnioski: Rozpowszechnienie u\u017cycia prostych narz\u0119dzi antropometrycznych (przede wszystkim C -Index i WHtR) wydaje si\u0119 by\u0107 korzystne, zw\u0142aszcza na szczeblu podstawowej opieki zdrowotnej. Narz\u0119dzia te mog\u0105 s\u0142u\u017cy\u0107 zar\u00f3wno do prewencji, jak i wczesnego wykrywania metabolicznych czynnik\u00f3w ryzyka choroby niedokrwiennej serca, a co za tym idzie potencjalnie \u015bmiertelnych konsekwencji incydent\u00f3w wie\u0144cowych u pacjent\u00f3w z NAFLD lub z innymi zaburzeniami metabolizmu.<\/jats:p>","DOI":"10.21164\/pomjlifesci.141","type":"journal-article","created":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T13:23:29Z","timestamp":1481203409000},"source":"Crossref","is-referenced-by-count":2,"title":["Metabolic risk factors of coronary heart disease in relation to\u00a0anthropometric measures in nonalcoholic fatty liver disease patients following dietary intervention"],"prefix":"10.21164","volume":"62","author":[{"given":"Ma\u0142gorzata","family":"Kaczorowska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Ryterska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Ossowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominika","family":"Maciejewska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Sabinicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominika","family":"Jamio\u0142-Milc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Raszeja-Wyszomirska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Stachowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8816","published-online":{"date-parts":[[2016,12,8]]},"container-title":["Pomeranian Journal of Life Sciences"],"original-title":[],"link":[{"URL":"http:\/\/ojs.pum.edu.pl\/pomjlifesci\/article\/viewFile\/141\/113","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ojs.pum.edu.pl\/pomjlifesci\/article\/viewFile\/141\/113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T13:23:30Z","timestamp":1481203410000},"score":1,"resource":{"primary":{"URL":"http:\/\/ojs.pum.edu.pl\/pomjlifesci\/article\/view\/141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,8]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,12,8]]}},"URL":"https:\/\/doi.org\/10.21164\/pomjlifesci.141","relation":{},"ISSN":["2450-4637"],"issn-type":[{"value":"2450-4637","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12,8]]}}}