{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"Research Square"}],"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T09:24:52Z","timestamp":1772529892466,"version":"3.50.1"},"posted":{"date-parts":[[2025,8,25]]},"group-title":"In Review","reference-count":0,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2025,7,28]]},"abstract":"<title>Abstract<\/title>\n                <p>Digital self-guided single-session interventions (SSIs) provide a structured psychological intervention within one interaction. We crowdsourced 66 diverse 10-minute SSIs for depression and selected 11 for testing in a pre-registered \u201cmegastudy\u201d (ClinicalTrials.gov ID: NCT06856668). American adults (N = 7,505) experiencing elevated depressive symptoms were recruited online and randomly assigned to one of the 11 crowdsourced SSIs, a previously-validated active comparison SSI, or a control without intervention content. Nearly all SSIs boosted agency and hope for improvement immediately after completion (ds \u2264 0.37). However, only two significantly reduced depression at four-week follow-up (ds = 0.14 and 0.15). Unexpectedly, some SSIs may have decreased readiness to change at four weeks (ds \u2264 0.14). The most successful SSIs provided focused, engaging, and actionable guidance on a skill that directly addressed users\u2019 struggles. Future work should aim to leverage SSIs\u2019 short-term gains to promote longer-term behavior change or service engagement.<\/p>","DOI":"10.21203\/rs.3.rs-7236847\/v1","type":"posted-content","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T08:22:31Z","timestamp":1756110151000},"source":"Crossref","is-referenced-by-count":0,"title":["A Crowdsourced Megastudy of 12 Digital Single-Session Interventions for Depression in American Adults"],"prefix":"10.21203","author":[{"given":"Benjamin","family":"Kaveladze","sequence":"first","affiliation":[{"name":"University of California, Irvine, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Voelkel","sequence":"additional","affiliation":[{"name":"Cornell University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Stagnaro","sequence":"additional","affiliation":[{"name":"Yale 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