{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"Research Square"}],"indexed":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T12:32:27Z","timestamp":1709469147924},"posted":{"date-parts":[[2020,12,23]]},"group-title":"In Review","reference-count":0,"publisher":"Research Square Platform LLC","license":[{"start":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:00:00Z","timestamp":1608681600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2020,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p><jats:bold>Background:<\/jats:bold> Nowadays, rabbits and guinea pigs are frequently adopted as companion animals, representing a vehicle for the dissemination of potentially pathogenic and allergenic fungi to their tutors. This study aimed to characterize the cutaneous mycobiota of these species and evaluate the association between mycological cultures results and several variables related to these animals\u2019 husbandry. Hair and scales samples (n=102) were collected from 32 rabbits and 19 guinea pigs: 51 by pulling hairs surrounding lesions and collecting scales (if lesions present) or along the body of the animal (if absent); the other 51 samples were collected using Mackenzie\u2019s technique. Samples were inoculated in Sabouraud Chloramphenicol Agar and Dermatophyte Test Media and observed daily during the incubation period. Isolated fungal species were identified based on their macro and microscopic morphology. A questionnaire was provided to the animal\u2019s tutors to collect information on animal husbandry.<jats:bold>Results:<\/jats:bold> Most frequently isolated species corresponded to saprophytic fungi, such as <jats:italic>Aspergillus<\/jats:italic> spp., <jats:italic>Penicillium<\/jats:italic> spp., <jats:italic>Scopulariopsis <\/jats:italic>spp.; <jats:italic>Candida<\/jats:italic> sp. and<jats:italic> Rhodotorula<\/jats:italic> sp. were also found. Statistical analysis showed that a positive mycological culture was related with animal\u2019s age and the administration of ongoing medication, while the number of isolated fungal species was related with animal\u2019s species and outdoor access.<jats:bold>Conclusions:<\/jats:bold> These fungi have already been reported as responsible for mycotic infections in humans and animals, including dogs and cats, although they usually affect immunocompromised individuals. Therefore, these animals can represent a zoonotic risk, which may be related with animals age, species, ongoing medication and outdoor access.<\/jats:p>","DOI":"10.21203\/rs.3.rs-128988\/v1","type":"posted-content","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T20:55:10Z","timestamp":1608756910000},"source":"Crossref","is-referenced-by-count":0,"title":["Pet Rabbits (Oryctolagus Cuniculus) and Guinea Pigs (Cavia Porcellus) are Vehicles of Pathogenic and Allergenic Fungi"],"prefix":"10.21203","author":[{"given":"Raquel","family":"Abreu","sequence":"first","affiliation":[{"name":"CIISA \u2013 Centro de Investiga\u00e7\u00e3o Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade Te\u0301cnica, 1300-477 Lisboa"}]},{"given":"Soraia","family":"Pereira","sequence":"additional","affiliation":[{"name":"DEIO, Centro de Estat\u00edstica e Aplica\u00e7\u00f5es, Universidade de Lisboa"}]},{"given":"Anabela","family":"Ramos","sequence":"additional","affiliation":[{"name":"CIISA \u2013 Centro de Investiga\u00e7\u00e3o Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade Te\u0301cnica, 1300-477 Lisboa"}]},{"given":"Eva","family":"Cunha","sequence":"additional","affiliation":[{"name":"CIISA \u2013 Centro de Investiga\u00e7\u00e3o Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade Te\u0301cnica, 1300-477 Lisboa"}]},{"given":"Ana","family":"Reisinho","sequence":"additional","affiliation":[{"name":"CIISA \u2013 Centro de Investiga\u00e7\u00e3o Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade Te\u0301cnica, 1300-477 Lisboa"}]},{"given":"Tiago","family":"Marques","sequence":"additional","affiliation":[{"name":"Centre for Research into Ecological and Environmental Modelling, University of St Andrews; Departamento de Biologia Animal, Centro de Estat\u00edstica e Aplica\u00e7\u00f5es, Universidade de Lisboa"}]},{"given":"Manuela","family":"Oliveira","sequence":"additional","affiliation":[{"name":"CIISA \u2013 Centro de Investiga\u00e7\u00e3o Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterin\u00e1ria, Universidade de Lisboa, Avenida da Universidade Te\u0301cnica, 1300-477 Lisboa"}]}],"member":"8761","container-title":[],"original-title":[],"link":[{"URL":"https:\/\/www.researchsquare.com\/article\/rs-128988\/v1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.researchsquare.com\/article\/rs-128988\/v1.html","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:42:02Z","timestamp":1659055322000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.researchsquare.com\/article\/rs-128988\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.21203\/rs.3.rs-128988\/v1","relation":{"is-preprint-of":[{"id-type":"doi","id":"10.51585\/gjm.2021.3.0010","asserted-by":"subject"}]},"subject":[],"published":{"date-parts":[[2020,12,23]]},"subtype":"preprint"}}