{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"Research Square"}],"indexed":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T04:04:24Z","timestamp":1745035464532,"version":"3.40.4"},"posted":{"date-parts":[[2025,4,18]]},"group-title":"In Review","reference-count":0,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2025,4,16]]},"abstract":"<title>Abstract<\/title>\n        <p>In 2024, unprecedented outbreaks of dengue virus (DENV) and Oropouche virus (OROV) were reported in Latin America and the Caribbean. We describe a case of co-infection with DENV serotype 3 and OROV imported into Portugal from Cuba. RT-PCR and next-generation sequencing confirmed the presence of both viruses in a 35-year-old male patient. Our findings highlight the importance of comprehensive multi-arbovirus diagnostics, particularly in travelers from regions experiencing concurrent outbreaks.<\/p>","DOI":"10.21203\/rs.3.rs-6466047\/v1","type":"posted-content","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T03:54:21Z","timestamp":1744948461000},"source":"Crossref","is-referenced-by-count":0,"title":["Case report: Dengue virus serotype 3 and Oropouche virus co-infection in a Cuban traveller diagnosed in Portugal, November 2024"],"prefix":"10.21203","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7258-1439","authenticated-orcid":false,"given":"L\u00edbia","family":"Z\u00e9-Z\u00e9","sequence":"first","affiliation":[{"name":"INSA, Centre for Vectors and Infectious Diseases Research, National Institute of Health Doctor Ricardo Jorge, Avenida da Liberdade, \u00c1guas de Moura, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9733-0724","authenticated-orcid":false,"given":"Joana","family":"Laranjinha","sequence":"additional","affiliation":[{"name":"Braga Local Health Unit, Braga Hospital"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3767-2209","authenticated-orcid":false,"given":"V\u00edtor","family":"Borges","sequence":"additional","affiliation":[{"name":"INSA, Genomics and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Doctor Ricardo Jorge, Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3775-8187","authenticated-orcid":false,"given":"Ana Lu\u00edsa","family":"Gra\u00e7a","sequence":"additional","affiliation":[{"name":"Braga Local Health Unit, Braga Hospital"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3955-0117","authenticated-orcid":false,"given":"Daniel","family":"Sobral","sequence":"additional","affiliation":[{"name":"INSA, Genomics and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Doctor Ricardo Jorge, Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4548-4606","authenticated-orcid":false,"given":"Jo\u00e3o Dourado","family":"Santos","sequence":"additional","affiliation":[{"name":"INSA, Genomics and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Doctor Ricardo Jorge, Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8512-9940","authenticated-orcid":false,"given":"Ana Cl\u00e1udia","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Braga Local Health Unit, Braga Hospital"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8839-2798","authenticated-orcid":false,"given":"Nuno Rodrigues","family":"Faria","sequence":"additional","affiliation":[{"name":"MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, Sir Michael Uren Hub, 86 Wood Lane, London W12 0BZ, United Kingdom"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2697-2399","authenticated-orcid":false,"given":"Jo\u00e3o Paulo","family":"Gomes","sequence":"additional","affiliation":[{"name":"INSA, Genomics and Bioinformatics Unit, Department of Infectious Diseases, National Institute of Health Doctor Ricardo Jorge, Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0065-9000","authenticated-orcid":false,"given":"Maria Jo\u00e3o","family":"Alves","sequence":"additional","affiliation":[{"name":"INSA, Centre for Vectors and Infectious Diseases Research, National Institute of Health Doctor Ricardo Jorge, Avenida da Liberdade, \u00c1guas de Moura, Portugal"}]}],"member":"297","container-title":[],"original-title":[],"link":[{"URL":"https:\/\/www.researchsquare.com\/article\/rs-6466047\/v1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.researchsquare.com\/article\/rs-6466047\/v1.html","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T03:54:21Z","timestamp":1744948461000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.researchsquare.com\/article\/rs-6466047\/v1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,18]]},"references-count":0,"URL":"https:\/\/doi.org\/10.21203\/rs.3.rs-6466047\/v1","relation":{},"subject":[],"published":{"date-parts":[[2025,4,18]]},"subtype":"preprint"}}