{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T05:20:52Z","timestamp":1786684852334,"version":"build-2736575974"},"reference-count":42,"publisher":"Japanese Society of Toxicology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Toxicol. Sci."],"published-print":{"date-parts":[[2005]]},"DOI":"10.2131\/jts.30.195","type":"journal-article","created":{"date-parts":[[2005,9,2]],"date-time":"2005-09-02T05:55:32Z","timestamp":1125640532000},"page":"195-206","source":"Crossref","is-referenced-by-count":44,"title":["EFFECTS OF MALE REPRODUCTIVE TOXICANTS ON GENE EXPRESSION IN RAT TESTES"],"prefix":"10.2131","volume":"30","author":[{"given":"Tamio","family":"FUKUSHIMA","sequence":"first","affiliation":[{"name":"Worldwide Safety Sciences, Pfizer Global Research & Development, Nagoya Laboratories, Pfizer Japan Inc."},{"name":"Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshinori","family":"YAMAMOTO","sequence":"additional","affiliation":[{"name":"Worldwide Safety Sciences, Pfizer Global Research & Development, Nagoya Laboratories, Pfizer Japan Inc."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"KIKKAWA","sequence":"additional","affiliation":[{"name":"Worldwide Safety Sciences, Pfizer Global Research & Development, Nagoya Laboratories, Pfizer Japan Inc."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimasa","family":"HAMADA","sequence":"additional","affiliation":[{"name":"Worldwide Safety Sciences, Pfizer Global Research & Development, Nagoya Laboratories, Pfizer Japan Inc."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"KOMIYAMA","sequence":"additional","affiliation":[{"name":"Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University"},{"name":"Center for Environment, Health and Field Sciences, Chiba University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chisato","family":"MORI","sequence":"additional","affiliation":[{"name":"Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University"},{"name":"Environmental Health Science Project for Future Generations, Graduate School of Medicine, Chiba University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuo","family":"HORII","sequence":"additional","affiliation":[{"name":"Worldwide Safety Sciences, Pfizer Global Research & Development, Nagoya Laboratories, Pfizer Japan Inc."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"898","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/mrd.10178","volume":"63","author":"Adachi, T., Komiyama, M., Ono, Y., Koh, K-B., Sakurai, K., Shibayama, T., Kato, M., Yoshikawa, T., Seki, N., Iguchi, T. and Mori, C.","year":"2002","journal-title":"Mol. Reprod. Dev.","ISSN":"https:\/\/id.crossref.org\/issn\/1040-452X","issn-type":"print"},{"key":"2","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/mrd.1092","volume":"60","author":"Aguilar-Mahecha, A., Hales, B. F. and Robaire, B.","year":"2001","journal-title":"Mol Reprod.","ISSN":"https:\/\/id.crossref.org\/issn\/0386-5495","issn-type":"print"},{"key":"3","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1289\/ehp.6683","volume":"112","author":"Amin, R.P., Vickers, A.E., Sistare, F., Thompson, K.L., Roman, R.J., Lawton, M., Kramer, J., Hamadeh, H.K., Collins, J., Grissom, S., Bennett, L., Tucker, C.J., Wild, S., Kind, C., Oreffo, V., Davis, J. W.","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.26.15675"},{"key":"5","first-page":"1094","volume":"1","author":"Baron, J.M., Connell, A.M., Lennard-Jones, J.E. and Jones, F.A.","year":"1962","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(94)00709-8"},{"key":"7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1146\/annurev.pharmtox.43.100901.135930","volume":"43","author":"Boekelheide, K., Fleming, S.L., Allio, T., Embree-Ku, M.E., Hall, S.J., Johnson, K.J., Kwon, E.J., Patel, S.R., Rasoulpour, R.J., Schoenfeld, H.A. and Thompson, S.","year":"2003","journal-title":"Annu. Rev. Pharmacol. Toxicol.","ISSN":"https:\/\/id.crossref.org\/issn\/0362-1642","issn-type":"print"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfg064"},{"key":"9","first-page":"111","volume":"34","author":"Carreau, S.","year":"1996","journal-title":"Folia. Histochem. Cytobiol.","ISSN":"https:\/\/id.crossref.org\/issn\/0015-5586","issn-type":"print"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4800(83)90082-5"},{"key":"11","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/j.1939-4640.1984.tb00803.x","volume":"5","author":"Chapin, R.E., Dutton, S.L., Ross, M.D., Sumrell, B.M. and Lamb, J.C.","year":"1984","journal-title":"J. Androl.","ISSN":"https:\/\/id.crossref.org\/issn\/0196-3635","issn-type":"print"},{"key":"12","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0272-0590(85)90099-5","volume":"5","author":"Chapin, R.E., Dutton, S.L., Ross, M.D., Swaisgood, R.R. and Lamb, J.C.","year":"1985","journal-title":"Fundam. Appl. Toxicol.","ISSN":"https:\/\/id.crossref.org\/issn\/0272-0590","issn-type":"print"},{"key":"13","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0014-4800(86)90020-1","volume":"45","author":"Creasy, D.M., Beech, L.M., Gray, T.J. and Butler, W.H.","year":"1986","journal-title":"Exp. Mol. Pathol.","ISSN":"https:\/\/id.crossref.org\/issn\/0014-4800","issn-type":"print"},{"key":"14","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/toxsci\/kfg196","volume":"75","author":"Longueville, F., Atienzar, F. A., Marcq, L., Dufrane, S., Evrard, S., Wouters, L., Leroux, F., Bertholet, V., Gerin, B., Whomsley, R., Arnould, T., Remacle, J. and Canning, M.","year":"2003","journal-title":"Toxicol. Sci.","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"key":"15","doi-asserted-by":"crossref","first-page":"482","DOI":"10.2307\/2528490","author":"Dunnet, C.W.","year":"1964","ISSN":"https:\/\/id.crossref.org\/issn\/0006-341X","issn-type":"print"},{"key":"16","first-page":"23","volume":"4","author":"Eddy, E.M.","year":"1999","journal-title":"J. Reprod. Fertil.","ISSN":"https:\/\/id.crossref.org\/issn\/0022-4251","issn-type":"print"},{"key":"17","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1093\/toxsci\/kfi071","volume":"85","author":"Fukushima, T., Kato, M., Adachi, T., Hamada, Y., Horimoto, M., Komiyama, M., Mori, C. and Horii, I.","year":"2005","journal-title":"Toxicol. Sci.","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(99)00061-1"},{"key":"19","first-page":"259","volume":"6","author":"Huleihel, M. and Lunenfeld, E.","year":"2004","journal-title":"Asian J Androl.","ISSN":"https:\/\/id.crossref.org\/issn\/1008-682X","issn-type":"print"},{"key":"20","first-page":"29A","volume":"57","author":"Isobe, Y., Horimoto, M., Tachibana, M. and Kawashima, K.","year":"1998","journal-title":"Teratology","ISSN":"https:\/\/id.crossref.org\/issn\/0040-3709","issn-type":"print"},{"key":"21","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/01485019408987821","volume":"33","author":"Ito, N., Nanbu, A., Tachiki, H., Akagashi, K., Nitta, T., Mikuma, N., Tsukamoto, T. and Kumamoto, Y.","year":"1994","journal-title":"Arch. Androl.","ISSN":"https:\/\/id.crossref.org\/issn\/0148-5016","issn-type":"print"},{"key":"22","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1210\/endo.141.2.7334","volume":"141","author":"Johnson, K.J., Patel, S.R. and Boekelheide, K.","year":"2000","journal-title":"Endocrinology.","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"key":"23","first-page":"227","volume":"3","author":"Kaurm, P. and Bansal, M. P.","year":"2004","journal-title":"Asian. J. Androl.","ISSN":"https:\/\/id.crossref.org\/issn\/1008-682X","issn-type":"print"},{"key":"24","first-page":"276","volume":"2","author":"Levi, A. J., Fisher, A. M., Hughes, L. and Hendry, W. F.","year":"1979","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"key":"25","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1093\/toxsci\/kfg073","volume":"73","author":"L?e, A., Hildebrand, H., Bach, U., Dingermann, T. and Ahr, H.J.","year":"2003","journal-title":"Toxicol. Sci.","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"4","key":"26","doi-asserted-by":"crossref","first-page":"407","DOI":"10.2131\/jts.20.4_407","volume":"20","author":"MATSUI H","year":"1995","journal-title":"J. Toxicol. Sci.","ISSN":"https:\/\/id.crossref.org\/issn\/0388-1350","issn-type":"print"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1042\/0264-6021:3400309"},{"issue":"2","key":"28","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0041-008X(80)90422-6","volume":"53","year":"1980","journal-title":"Toxicol. Appl. Pharmacol.","ISSN":"https:\/\/id.crossref.org\/issn\/0041-008X","issn-type":"print"},{"key":"29","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1095\/biolreprod52.2.419","volume":"52","author":"Rappaport, M.S. and Smith, E.P.","year":"1995","journal-title":"Biol. Reprod.","ISSN":"https:\/\/id.crossref.org\/issn\/0006-3363","issn-type":"print"},{"key":"30","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1093\/oxfordjournals.humrep.a137952","volume":"8","author":"Schaller, J., Glander, H. J. and Dethloff, J.","year":"1993","journal-title":"Hum. Reprod.","ISSN":"https:\/\/id.crossref.org\/issn\/0268-1161","issn-type":"print"},{"key":"31","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1210\/en.2002-221035","volume":"144","author":"Siu, M.K., Mruk, D.D., Lee, W.M. and Cheng, C.Y.","year":"2003","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"key":"32","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1210\/endo-127-6-2744","volume":"127","author":"Smith, E.P., Dickson, B.A. and Chernausek, S.D.","year":"1990","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"key":"33","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0040-8166(94)90015-9","volume":"26","author":"Suarez-Quian, C.A., Oke, B.O. and Radhakrishnan, B.","year":"1994","journal-title":"Tissue Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0040-8166","issn-type":"print"},{"key":"34","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0016-5085(79)90385-8","volume":"77","author":"Summers, R.W., Switz, D.M. and Sessions, J.T.","year":"1979","journal-title":"Result of drug treatment. Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"key":"35","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.0954-6820.1942.tb06841.x","volume":"110","author":"Svartz, N.","year":"1942","journal-title":"Acta Med. Scan","ISSN":"https:\/\/id.crossref.org\/issn\/0515-2917","issn-type":"print"},{"key":"36","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1289\/ehp.6676","volume":"112","author":"Thompson, K.L., Afshari, C.A., Amin, R.P., Bertram, T.A., Car, B., Cunningham, M., Kind, C., Kramer, J.A., Lawton, M., Mirsky, M., Naciff, J. M., Oreffo, V., Pine, P.S. and Sistare, F.D.","year":"2004","journal-title":"Environ. Health. Perspect."},{"key":"37","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/S0015-0282(16)44000-8","volume":"31","author":"Toth, A.","year":"1979","journal-title":"Fertil Steril.","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1007\/BF01246673"},{"key":"39","doi-asserted-by":"crossref","first-page":"4049","DOI":"10.1210\/endo.136.9.7544275","volume":"136","author":"Wang, D., Nagpal, M. L., Shimasaki, S., Ling, N. and Lin, T.","year":"1995","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"key":"40","first-page":"39","volume":"137","author":"Wang, J.E., Josefsen, G.M., Hansson, V. and Haugen, T.B.","year":"1998","journal-title":"Mol. Cell. Endocrinol.","ISSN":"https:\/\/id.crossref.org\/issn\/0303-7207","issn-type":"print"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/56.1.165"},{"issue":"Special","key":"42","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2131\/jts.25.SpecialIssue_129","volume":"25","author":"WATANABE T","year":"2000","journal-title":"Effects of cyclophosphamide on spermatogenesis. J. Toxicol. Sci.","ISSN":"https:\/\/id.crossref.org\/issn\/0388-1350","issn-type":"print"}],"container-title":["The Journal of Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jts\/30\/3\/30_3_195\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T03:23:14Z","timestamp":1620962594000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jts\/30\/3\/30_3_195\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.2131\/jts.30.195","relation":{},"ISSN":["0388-1350","1880-3989"],"issn-type":[{"value":"0388-1350","type":"print"},{"value":"1880-3989","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}