{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:23:42Z","timestamp":1789201422923,"version":"build-2803163510"},"reference-count":43,"publisher":"Japanese Society of Toxicology","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Toxicol. Sci."],"published-print":{"date-parts":[[2010]]},"DOI":"10.2131\/jts.35.871","type":"journal-article","created":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T06:08:27Z","timestamp":1291183707000},"page":"871-879","source":"Crossref","is-referenced-by-count":14,"title":["Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone"],"prefix":"10.2131","volume":"35","author":[{"given":"Morihiko","family":"Hirota","sequence":"first","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Motoyama","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mie","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Yanagi","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Kitagaki","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Kouzuki","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigenobu","family":"Hagino","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Itagaki","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Sasa","sequence":"additional","affiliation":[{"name":"Shiseido Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saori","family":"Kagatani","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tohoku University of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Setsuya","family":"Aiba","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Tohoku University of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"898","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830271141"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-1811(99)00005-5"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12065.x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"Alvarez, C., Garcia-Mata, R., Brandon, E. and Sztul, E. (2003): COPI recruitment is modulated by a Rab1b-dependent mechanism. Mol. Biol. Cell, <b>14<\/b>, 2116-2127.","DOI":"10.1091\/mbc.e02-09-0625"},{"key":"5","doi-asserted-by":"crossref","unstructured":"Basketter, D.A., Evans, P., Gerberick, G.F. and Kimber, I.A. (2002): Factors affecting thresholds in allergic contact dermatitis: safety and regulatory considerations. Contact Dermatitis, <b>47<\/b>, 1-6.","DOI":"10.1034\/j.1600-0536.2002.470101.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12026.x"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.23229.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/52.2.189"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(01)02341-2"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M412708200"},{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1042\/BJ20070379","volume":"407","author":"DE HEMPTINNE VIRGINIE","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/0264-6021","issn-type":"print"},{"issue":"10","key":"12","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1242\/jcs.110.10.1199","volume":"110","year":"1997","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9533","issn-type":"print"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Filomeni, G., Rotilio, G. and Ciriolo, M.R. (2003): Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway. FASEB J., <b>17<\/b>, 64-66.","DOI":"10.1096\/fj.02-0105fje"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2000.4111"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfh213"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1021\/bi982844p"},{"key":"17","unstructured":"Holzer, A.M., Kaplan, L.L. and Levis, W.R. (2006): Haptens as drugs: contact allergens are powerful topical immunomodulators. J. Drugs Dermatol.,<b> 5<\/b>, 410-416."},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.2131\/jts.31.149"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.2131\/jts.34.139"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.4.2416"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.229"},{"key":"23","doi-asserted-by":"crossref","unstructured":"Kim, S.J., Zhang, Z., Hitomi, E., Lee, Y.C. and Mukherjee, A.B. (2006): Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. Hum. Mol. Genet., <b>15<\/b>, 1826-1834.","DOI":"10.1093\/hmg\/ddl105"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2434516100"},{"key":"25","doi-asserted-by":"crossref","unstructured":"Lawrence, D.A., Song, R. and Weber, P. (1996): Surface thiols of human lymphocytes and their changes after <i>in vitro<\/i> and <i>in vivo <\/i>activation. J. Leukoc. Biol., <b>60<\/b>, 611-618.","DOI":"10.1002\/jlb.60.5.611"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(02)02245-2"},{"key":"27","doi-asserted-by":"crossref","unstructured":"Mielenz, D., Vettermann, C., Hampel, M., Lang, C., Avramidou, A., Karas, M. and J&auml;ck, H.M. (2005): Lipid rafts associate with intracellular B cell receptors and exhibit a B cell stage-specific protein composition. J. Immunol., <b>174<\/b>, 3508-3517.","DOI":"10.4049\/jimmunol.174.6.3508"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23624.x"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1021\/ac062292d"},{"key":"30","doi-asserted-by":"crossref","unstructured":"Nagai, H., Noguchi, T., Takeda, K. and Ichijo, H. (2007): Pathophysiological Roles of ASK1-MAP Kinase Signaling Pathways. J. Biochem. Mol. Biol., <b>40<\/b>, 1-6.","DOI":"10.5483\/BMBRep.2007.40.1.001"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4401378"},{"key":"32","doi-asserted-by":"crossref","unstructured":"Ryu, E.J., Harding, H.P., Angelastro, J.M., Vitolo, O.V., Ron, D. and Greene, L.A. (2002): Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson&rsquo;s disease. J. Neurosci., <b>22<\/b>, 10690-10698.","DOI":"10.1523\/JNEUROSCI.22-24-10690.2002"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(86)90516-6"},{"issue":"2","key":"34","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1042\/bj3300675","volume":"330","year":"1998","ISSN":"https:\/\/id.crossref.org\/issn\/0264-6021","issn-type":"print"},{"key":"35","unstructured":"Snedecor, G.M. and Cochan, W.G. (1989): Statistical Methods. 8<sup>th<\/sup> edn, pp.86-106, Iowa State Universary Press, Ames, IA, USA."},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.33.19551"},{"key":"37","doi-asserted-by":"crossref","unstructured":"Suzuki, M., Hirota, M., Hagino, S., Itagaki, H. and Aiba, S. (2009): Evaluation of changes of cell-surface thiols as a new biomarker for in vitro sensitization test. Toxicol. In Vitro, <b>23<\/b>, 687-696.","DOI":"10.1016\/j.tiv.2009.02.002"},{"key":"38","doi-asserted-by":"crossref","unstructured":"Urano, F., Wang, X., Bertolotti, A., Zhang, Y., Chung, P., Harding, H.P. and Ron, D. (2000): Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science, <b>287<\/b>, 664-666.","DOI":"10.1126\/science.287.5453.664"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00611-0"},{"key":"40","doi-asserted-by":"crossref","unstructured":"Wallenstein, S., Zucker, C.L. and Fleiss, J.L. (1980): Some statistical methods useful in circulation research. Circ. Res., <b>47<\/b>, 1-9.","DOI":"10.1161\/01.RES.47.1.1"},{"key":"41","doi-asserted-by":"crossref","unstructured":"Werner, C.J., Heyny-von Haussen, R., Mall, G. and Wolf, S. (2008): Proteome analysis of human substantia nigra in Parkinson&rsquo;s disease. Proteome Sci., <b>6<\/b>, 8.","DOI":"10.1186\/1477-5956-6-8"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1038\/nsb932"},{"key":"43","doi-asserted-by":"crossref","unstructured":"Zhu, B., Fukada, K., Zhu, H. and Kyprianou, N. (2006): Prohibitin and cofilin are intracellular effectors of transforming growth factor beta signaling in human prostate cancer cells. Cancer Res., <b>66<\/b>, 8640-8647.","DOI":"10.1158\/0008-5472.CAN-06-1443"}],"container-title":["The Journal of Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jts\/35\/6\/35_6_871\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,14]],"date-time":"2021-11-14T12:32:39Z","timestamp":1636893159000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jts\/35\/6\/35_6_871\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.2131\/jts.35.871","relation":{},"ISSN":["0388-1350","1880-3989"],"issn-type":[{"value":"0388-1350","type":"print"},{"value":"1880-3989","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]}}}