{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:59:38Z","timestamp":1787497178932,"version":"build-2736575974"},"reference-count":34,"publisher":"Japanese Society of Toxicology","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Toxicol. Sci."],"published-print":{"date-parts":[[2013]]},"DOI":"10.2131\/jts.38.671","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T05:34:58Z","timestamp":1378877698000},"page":"671-678","source":"Crossref","is-referenced-by-count":16,"title":["c-Fos immunoreactivity of neural cells in intoxication due to high-dose methamphetamine"],"prefix":"10.2131","volume":"38","author":[{"given":"Masafumi","family":"Tomita","sequence":"first","affiliation":[{"name":"Department of Medical Toxicology, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironobu","family":"Katsuyama","sequence":"additional","affiliation":[{"name":"Department of Public Health, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Natural Sciences, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Shibaike","sequence":"additional","affiliation":[{"name":"Department of Medical Toxicology, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Yoshinari","sequence":"additional","affiliation":[{"name":"Department of Medical Toxicology, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia Wei","family":"Tee","sequence":"additional","affiliation":[{"name":"Department of Medical Toxicology, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhisa","family":"Iwachidou","sequence":"additional","affiliation":[{"name":"Tissue Biology & Electron Microscopy Research Center, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Physiology 2, Kawasaki Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"898","reference":[{"key":"1","unstructured":"Ali, S.F., Newport, G.D. and Slikker, Jr.W. (1996): Methamphetamine-induced dopaminergic toxicity in mice. Role of environmental temperature and pharmacological agents. Ann. N.Y. Acad. Sci., 801<\/b>, 187-198."},{"key":"2","doi-asserted-by":"crossref","unstructured":"Bachtell, R.K., Tsivkovskaia, N.O. and Ryabinin, A.E. (2003): Identification of temperature-sensitive neural circuits in mice using c-Fos expression mapping. Brain Res., 960<\/b>, 157-164.","DOI":"10.1016\/S0006-8993(02)03807-6"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Boulant, J.A. (2000): Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clin. Infect. Dis., 31<\/b>, S157-S161.","DOI":"10.1086\/317521"},{"key":"4","doi-asserted-by":"crossref","unstructured":"Bowyer, J.F., Gough, B., Slikker, Jr.W., Lipe, G.W., Newport, G.D. and <\/b>Holson, R.R. (1993): Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats. Pharmacol. Biochem. Behav., 44<\/b>, 87-98.","DOI":"10.1016\/0091-3057(93)90284-Z"},{"key":"5","doi-asserted-by":"crossref","unstructured":"Cerri, M. and Morrison, S.F. (2005): Activation of lateral hypothalamic neurons stimulates brown adipose tissue thermogenesis. Neuroscience, 135<\/b>, 627-638.","DOI":"10.1016\/j.neuroscience.2005.06.039"},{"key":"6","doi-asserted-by":"crossref","unstructured":"Evanson, N.K., Tasker, J.G., Hill, M.N., Hillard, C.J. and Herman, J.P. (2010): Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signaling. Endocrinology, 151<\/b>, 4811-4819.","DOI":"10.1210\/en.2010-0285"},{"key":"7","unstructured":"Franklin, K.B.J. and Paxinos, G. (2007): in: The Mouse Brain in Stereotaxic Coordinates. 3rd edn. Academic Press, New York."},{"key":"8","doi-asserted-by":"crossref","unstructured":"Fujimoto, Y., Kitaichi, K., Nakayama, H., Ito, Y., Takagi, K., Takagi, K. and Hasegawa, T. (2007): The pharmacokinetic properties of methamphetamine in rats with previous repeated exposure to methamphetamine: the differences between Long-Evans and Wistar rats. Exp. Anim., 5<\/i>6<\/b>, 119-129.","DOI":"10.1538\/expanim.56.119"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Herring, N.R., Schaefer, T.L., Tang, P.H., Skelton, M.R., Lucot, J.P., Gudelsky, G.A., Vorhees, C.V., and Williams, M.T. (2008): Comparison of time-dependent effects of (+)-methamphetamine or forced swim on monoamines, corticosterone, glucose, creatine, and creatinine in rats. BMC Neurosci., 9<\/b>, 49. ","DOI":"10.1186\/1471-2202-9-49"},{"key":"10","unstructured":"Ishigami, A., Kubo, S., Gotohda, T. and Tokunaga, I. (2003): The application of immunohistochemical findings in the diagnosis in methamphetamine-related death - two forensic autopsy cases-. J. Med. Invest., 50<\/b>, 112-116."},{"key":"11","doi-asserted-by":"crossref","unstructured":"Karila, L., Weinstein, A., Aubin, H.J., Benyamina, A., Reynaud, M. and Batki, S.L. (2010): Pharmacological approaches to methamphetamine dependence: a focused review. Br. J. Clin. Pharmacol., 69<\/b>, 578-592.","DOI":"10.1111\/j.1365-2125.2010.03639.x"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Kikuchi-Utsumi, K., Ishizaka, M., Matsumura, N., Watabe, M., Aoyama, K., Sasakawa, N. and Nakaki, T. (2013): Involvement of the α1D-adrenergic Receptor in Methamphetamine-Induced Hyperthermia and Neurotoxicity in Rats. Neurotox. Res., 24<\/b>, 130-138.","DOI":"10.1007\/s12640-012-9369-9"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Kiyohara, T., Miyata, S., Nakamura, T., Shido, O., Nakashima, T. and Shibata, M. (1995): Differences in Fos expression in the rat brains between cold and warm ambient exposures. Brain Res. Bull., 38<\/b>, 193-201.","DOI":"10.1016\/0361-9230(95)00093-T"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Kojima, T., Une, I., Yashiki, M., Noda, J., Sakai, K. and Yamamoto, K. (1984): A fatal methamphetamine poisoning associated with hyperpyrexia. Forensic Sci. Int., 24<\/b>, 87-93.","DOI":"10.1016\/0379-0738(84)90156-7"},{"key":"15","unstructured":"Lee, Y., Hamamura, T., Ohashi, K., Miki, M., Fujiwara, Y., Kuroda, S. (2000): Carbamazepine suppresses methamphetamine-induced Fos expression in a regionally specific manner in the rat brain. Possible neural substrates responsible for antimanic effects of mood stabilizers. Neuropsychopharmacology, 22<\/b>, 530-537."},{"key":"16","doi-asserted-by":"crossref","unstructured":"Levi, M.S., Divine, B., Hanig, J.P., Doerge, D.R., Vanlandingham, M.M., George, N.I., Twaddle, N.C. and Bowyer, J.F. (2012): A comparison of methylphenidate-, amphetamine-, and methamphetamine-induced hyperthermia and neurotoxicity in male Sprague–Dawley rats during the waking (lights off) cycle. Neurotoxicol. Teratol., 34<\/b>, 253-262.","DOI":"10.1016\/j.ntt.2012.01.007"},{"key":"17","doi-asserted-by":"crossref","unstructured":"Maxwell, J.C. and Rutkowski, B.A. (2008): The prevalence of methamphetamine and amphetamine abuse in North America: a review of the indicators, 1992-2007. Drug Alcohol Rev., 27<\/b>, 229-235.","DOI":"10.1080\/09595230801919460"},{"key":"18","doi-asserted-by":"crossref","unstructured":"McGivern, R.F., Zuloaga, D.G. and Handa, R.J. (2009): Sex differences in stress-induced hyperthermia in rats: restraint versus confinement. Physiol. Behav., 98<\/b>, 416-420.","DOI":"10.1016\/j.physbeh.2009.07.004"},{"key":"19","doi-asserted-by":"crossref","unstructured":"Nakajima, A., Yamada, K., He, J., Zeng, N., Nitta, A. and Nabeshima, T. (2004): Anatomical substrates for the discriminative stimulus effects of methamphetamine in rats. J. Neurochem., 91<\/b>, 308-317.","DOI":"10.1111\/j.1471-4159.2004.02705.x"},{"key":"20","doi-asserted-by":"crossref","unstructured":"Nakamura, K. (2011): Central circuitries for body temperature regulation and fever. Am. J. Physiol. Regul. Integr. Comp. Physiol., 301<\/b>, R1207-R1228.","DOI":"10.1152\/ajpregu.00109.2011"},{"key":"21","doi-asserted-by":"crossref","unstructured":"Numachi, Y., Ohara, A., Yamashita, M., Fukushima, S., Kobayashi, H., Hata, H., Watanabe, H., Hall, F.S., Lesch, K.-P., Murphy, D. L., Uhl, G.R. and Sora, I. (2007): Methamphetamine-induced hyperthermia and lethal toxicity: Role of the dopamine and serotonin transporters. Eur. J. Pharmacol., 572<\/b>, 120-128.","DOI":"10.1016\/j.ejphar.2007.06.022"},{"key":"22","doi-asserted-by":"crossref","unstructured":"Otake, K., Kin, K. and Nakamura, Y. (2002): Fos expression in afferents to the rat midline thalamus following immobilization stress. Neurosci. Res., 43<\/b>, 269-282.","DOI":"10.1016\/S0168-0102(02)00042-1"},{"key":"23","doi-asserted-by":"crossref","unstructured":"Pilgrim, J.L., Gerostamoulos, D., Drummer, O.H. and Bollmann, M. (2009): Involvement of amphetamines in sudden and unexpected death. J. Forensic Sci., 54<\/b>, 478-485.","DOI":"10.1111\/j.1556-4029.2008.00949.x"},{"key":"24","doi-asserted-by":"crossref","unstructured":"Rau, V. and Grijalva, C.V. (2004): Indomethacin attenuates hyperthermia produced by anterior coronal lateral hypothalamic knife cuts. Brain Res. Bull., 64<\/b>, 53-58.","DOI":"10.1016\/j.brainresbull.2004.05.004"},{"key":"25","doi-asserted-by":"crossref","unstructured":"Rhodes, J.S., Ryabinin, A.E. and Crabbe, J.C. (2005): Patterns of brain activation associated with contextual conditioning to methamphetamine in mice. Behav. Neurosci., 119<\/b>, 759-771.","DOI":"10.1037\/0735-7044.119.3.759"},{"key":"26","doi-asserted-by":"crossref","unstructured":"Seminerio, M.J., Robson, M.J., McCurdy, C.R. and Matsumoto, R.R. (2012): Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1β mRNA expression in the hypothalamus. Eur. J. Pharmacol., 691<\/b>, 103-109.","DOI":"10.1016\/j.ejphar.2012.07.029"},{"key":"27","doi-asserted-by":"crossref","unstructured":"Szumlinski, K.K., Haskew, R.E., Balogun, M.Y., Maisonneuve, I.M. and Glick, S.D. (2001): Iboga compounds reverse the behavioural disinhibiting and corticosterone effects of acute methamphetamine: Implications for their antiaddictive properties. Pharmacol. Biochem. Behav., 69<\/b>, 485-491.","DOI":"10.1016\/S0091-3057(01)00564-0"},{"key":"28","doi-asserted-by":"crossref","unstructured":"Tani, K., Iyo, M., Matsumoto, H., Kawai, M., Suzuki, K., Iwata, Y., Won, T., Tsukamoto, T., Sekine, Y., Sakanoue, M., Hashimoto, K., Ohashi, Y., Takei, N. and Mori, N. (2001): The effects of dentate granule cell destruction on behavioural activity and Fos protein expression induced by systemic methamphetamine in rats. Br. J. Pharmacol., 134<\/b>, 1411-1418.","DOI":"10.1038\/sj.bjp.0704370"},{"key":"29","doi-asserted-by":"crossref","unstructured":"Thiriet, N., Zwiller, J. and Ali, S.F. (2001): Induction of the immediate early genes egr-1 and c-fos by methamphetamine in mouse brain. Brain Res., 919<\/b>, 31-40.","DOI":"10.1016\/S0006-8993(01)02991-2"},{"key":"30","doi-asserted-by":"crossref","unstructured":"Umino, A., Nishikawa, T. and Takahashi, K. (1995): Methamphetamine-induced nuclear c-Fos in rat brain regions. Neurochem. Int., 26<\/b>, 85-90.","DOI":"10.1016\/0197-0186(94)00096-D"},{"key":"31","unstructured":"Yoshida, S., Kinoshita, H., Tatara, T., Tashiro, C., Nishiguchi, M., Ouchi, H., Minami, T. and Hishida, S. (2012): Involvement of glucocorticoid receptor on hyperpyrexia induced by methamphetamine administration. Soud. Lek., 57<\/b>, 66-68."},{"key":"32","doi-asserted-by":"crossref","unstructured":"Zaretskaia, M.V., Zaretsky, D.V., Sarkar, S., Shekhar, A. and DiMicco, J.A. (2008): Induction of Fos-immunoreactivity in the rat brain following disinhibition of the dorsomedial hypothalamus. Brain Res., 1200<\/b>, 39-50.","DOI":"10.1016\/j.brainres.2008.01.018"},{"key":"33","doi-asserted-by":"crossref","unstructured":"Zhang, Y.Y., Zhu, W.X., Cao, G.H., Cui, X.Y. and Ai, H.B. (2009): c-Fos expression in the supraoptic nucleus is the most intense during different durations of restraint water-immersion stress in the rat. J. Physiol. Sci., 59<\/b>, 367-375.","DOI":"10.1007\/s12576-009-0044-8"},{"key":"34","doi-asserted-by":"crossref","unstructured":"Zombeck, J.A., Lewicki, A.D., Patel, K., Gupta, T. and Rhodes, J.S. (2010): Patterns of neural activity associated with differential acute locomotor stimulation to cocaine and methamphetamine in adolescent versus adult male C57BL\/6J mice. Neuroscience, 165<\/b>, 1087-1099.","DOI":"10.1016\/j.neuroscience.2009.11.038"}],"container-title":["The Journal of Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jts\/38\/5\/38_671\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T23:39:04Z","timestamp":1620949144000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jts\/38\/5\/38_671\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.2131\/jts.38.671","relation":{},"ISSN":["0388-1350","1880-3989"],"issn-type":[{"value":"0388-1350","type":"print"},{"value":"1880-3989","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}