{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T09:22:16Z","timestamp":1738488136054,"version":"3.35.0"},"reference-count":42,"publisher":"Japanese Society of Toxicology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Toxicol. Sci."],"published-print":{"date-parts":[[2025]]},"DOI":"10.2131\/jts.50.83","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T22:19:45Z","timestamp":1738361985000},"page":"83-95","source":"Crossref","is-referenced-by-count":0,"title":["The effects of anemia on the timing of pubertal onset in female rats"],"prefix":"10.2131","volume":"50","author":[{"given":"Mariko","family":"Shimada","sequence":"first","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Hosokawa","sequence":"additional","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Ihara","sequence":"additional","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Ogata","sequence":"additional","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumasa","family":"Iwashita","sequence":"additional","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoko","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Asano","sequence":"additional","affiliation":[{"name":"Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"898","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"Abreu, A.P. and Kaiser, U.B. (2016): Pubertal development and regulation. Lancet Diabetes Endocrinol., <b>4<\/b>, 254-264.","DOI":"10.1016\/S2213-8587(15)00418-0"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Andersson, N., Arena, M., Auteri, D., Barmaz, S., Grignard, E., Kienzler, A., Lepper, P., Lostia, A.M., Munn, S., Parra Morte, J.M., Pellizzato, F., Tarazona, J., Terron, A. and Van der Linden, S.; European Chemical Agency (ECHA) and European Food Safety Authority (EFSA) with the technical support of the Joint Research Centre (JRC). (2018): Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528\/2012 and (EC) No 1107\/2009. EFSA J., <b>16<\/b>, e05311.","DOI":"10.2903\/j.efsa.2018.5311"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Ashby, J., Owens, W., Deghenghi, R. and Odum, J. (2002): Concept evaluation: an assay for receptor-mediated and biochemical antiestrogens using pubertal rats. Regul. Toxicol. Pharmacol., <b>35<\/b>, 393-397.","DOI":"10.1006\/rtph.2002.1557"},{"key":"4","doi-asserted-by":"crossref","unstructured":"Berger, J. (2007): Phenylhydrazine haematotoxicity. J. Appl. Biomed., <b>5<\/b>, 125-130.","DOI":"10.32725\/jab.2007.017"},{"key":"5","doi-asserted-by":"crossref","unstructured":"Carney, E.W., Zablotny, C.L., Marty, M.S., Crissman, J.W., Anderson, P., Woolhiser, M. and Holsapple, M. (2004): The effects of feed restriction during in utero and postnatal development in rats. Toxicol. Sci., <b>82<\/b>, 237-249.","DOI":"10.1093\/toxsci\/kfh249"},{"key":"6","doi-asserted-by":"crossref","unstructured":"Chen, X.Q., Du, J.Z. and Wang, Y.S. (2004): Regulation of hypoxia-induced release of corticotropin-releasing factor in the rat hypothalamus by norepinephrine. Regul. Pept., <b>119<\/b>, 221-228.","DOI":"10.1016\/j.regpep.2004.02.005"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Dryden, L.P., Hartman, A.M. and Cary, C.A. (1954): Influence of vitamin B12 upon vaginal patency in the rat. Proc. Soc. Exp. Biol. Med., <b>87<\/b>, 195-197.","DOI":"10.3181\/00379727-87-21332"},{"key":"8","doi-asserted-by":"crossref","unstructured":"Falsetti, L., Gambera, A., Barbetti, L. and Specchia, C. (2002): Long-term follow-up of functional hypothalamic amenorrhea and prognostic factors. J. Clin. Endocrinol. Metab., <b>87<\/b>, 500-505.","DOI":"10.1210\/jcem.87.2.8195"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Frisch, R.E., Hegsted, D.M. and Yoshinaga, K. (1975): Body weight and food intake at early estrus of rats on a high-fat diet. Proc. Natl. Acad. Sci. USA, <b>72<\/b>, 4172-4176.","DOI":"10.1073\/pnas.72.10.4172"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Gheith, I. and El-Mahmoudy, A. (2018): Laboratory evidence for the hematopoietic potential of Beta vulgaris leaf and stalk extract in a phenylhydrazine model of anemia. Braz. J. Med. Biol. Res., <b>51<\/b>, e7722.","DOI":"10.1590\/1414-431x20187722"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Gomes, I.C., Melo, H.N., Melo, S.I., Menezes, N.V., Dantas, T.V. and Cipolotti, R. (2017): Growth and puberty in a prospective cohort of patients with sickle-cell anaemia: an assessment over ten years abstract. J. Hum. Growth Dev., <b>27<\/b>, 91-98.","DOI":"10.7322\/jhgd.127681"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Grill, C.J., Cohick, W.S. and Sherman, A.R. (2001): Postpubertal development of the rat mammary gland is preserved during iron deficiency. J. Nutr., <b>131<\/b>, 1444-1448.","DOI":"10.1093\/jn\/131.5.1444"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Hwang, G.S., Chen, C.C., Chou, J.C., Chang, L.L., Kan, S.F., Lai, W.H., Lieu, F.K., Hu, S., Wang, P.S. and Wang, S.W. (2017): Stimulatory Effect of Intermittent Hypoxia on the Production of Corticosterone by Zona Fasciculata-Reticularis Cells in Rats. Sci. Rep., <b>7<\/b>, 9035.","DOI":"10.1038\/s41598-017-07054-6"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Kim, H.S., Shin, J.H., Moon, H.J., Kim, T.S., Kang, I.H., Seok, J.H., Kim, I.Y., Park, K.L. and Han, S.Y. (2002): Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide. Toxicol. Sci., <b>67<\/b>, 52-62.","DOI":"10.1093\/toxsci\/67.1.52"},{"key":"15","doi-asserted-by":"crossref","unstructured":"Kinsey-Jones, J.S., Li, X.F., Knox, A.M., Lin, Y.S., Milligan, S.R., Lightman, S.L. and O\u2019Byrne, K.T. (2010): Corticotrophin-releasing factor alters the timing of puberty in the female rat. J. Neuroendocrinol., <b>22<\/b>, 102-109.","DOI":"10.1111\/j.1365-2826.2009.01940.x"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Kojima, S., Haruta, J., Enomoto, A., Fujisawa, H., Harada, T. and Maita, K. (1999): Age-related hematological changes in normal F344 rats: during the neonatal period. Exp. Anim., <b>48<\/b>, 153-159.","DOI":"10.1538\/expanim.48.153"},{"key":"17","doi-asserted-by":"crossref","unstructured":"Laws, S.C., Stoker, T.E., Ferrell, J.M., Hotchkiss, M.G. and Cooper, R.L. (2007): Effects of altered food intake during pubertal development in male and female wistar rats. Toxicol. Sci., <b>100<\/b>, 194-202.","DOI":"10.1093\/toxsci\/kfm219"},{"key":"18","doi-asserted-by":"crossref","unstructured":"Li, X.F., Adekunbi, D.A., Alobaid, H.M., Li, S., Pilot, M., Lightman, S.L. and O\u2019Byrne, K.T. (2019): Role of the posterodorsal medial amygdala in predator odour stress-induced puberty delay in female rats. J. Neuroendocrinol., <b>31<\/b>, e12719.","DOI":"10.1111\/jne.12719"},{"key":"19","doi-asserted-by":"crossref","unstructured":"Li, X.F., Knox, A.M. and O\u2019Byrne, K.T. (2010): Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female. Brain Res., <b>1364<\/b>, 153-163.","DOI":"10.1016\/j.brainres.2010.08.036"},{"key":"20","doi-asserted-by":"crossref","unstructured":"Manzano Nieves, G., Schilit Nitenson, A., Lee, H.I., Gallo, M., Aguilar, Z., Johnsen, A., Bravo, M. and Bath, K.G. (2019): Early Life Stress Delays Sexual Maturation in Female Mice. Front. Mol. Neurosci., <b>12<\/b>, 27.","DOI":"10.3389\/fnmol.2019.00027"},{"key":"21","doi-asserted-by":"crossref","unstructured":"Marty, M.S., Crissman, J.W. and Carney, E.W. (1999): Evaluation of the EDSTAC female pubertal assay in CD rats using 17beta-estradiol, steroid biosynthesis inhibitors, and a thyroid inhibitor. Toxicol. Sci., <b>52<\/b>, 269-277.","DOI":"10.1093\/toxsci\/52.2.269"},{"key":"22","doi-asserted-by":"crossref","unstructured":"McDonald, P.G. and Doughty, C. (1972): Comparison of the effect of neonatal administration of testosterone and dihydrotestosterone in the female rat. J. Reprod. Fertil., <b>30<\/b>, 55-62.","DOI":"10.1530\/jrf.0.0300055"},{"key":"23","doi-asserted-by":"crossref","unstructured":"Milman, N. (2011): Anemia--still a major health problem in many parts of the world! Ann. Hematol., <b>90<\/b>, 369-377.","DOI":"10.1007\/s00277-010-1144-5"},{"key":"24","doi-asserted-by":"crossref","unstructured":"OECD (2001): Test No. 416: Two-Generation Reproduction Toxicity. OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris. https:\/\/doi.org\/10.1787\/9789264070868-en, Accessed Sep 12, 2024.","DOI":"10.1787\/9789264070868-en"},{"key":"25","doi-asserted-by":"crossref","unstructured":"OECD (2007): Test No. 426: Developmental Neurotoxicity Study. OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris. https:\/\/doi.org\/10.1787\/9789264067394-en, Accessed Sep 12, 2024.","DOI":"10.1787\/9789264067394-en"},{"key":"26","doi-asserted-by":"crossref","unstructured":"OECD (2009): Guidance Document for Histologic Evaluation of Endocrine and Reproductive Tests in Rodents. OECD Series on Testing and Assessment, No. 106, OECD Publishing, Paris. https:\/\/doi.org\/10.1787\/cd68c07d-en. Accessed Sep 12, 2024.","DOI":"10.1787\/cd68c07d-en"},{"key":"27","doi-asserted-by":"crossref","unstructured":"OECD (2018): Test No. 443: Extended One-Generation Reproductive Toxicity Study. OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris. https:\/\/doi.org\/10.1787\/9789264185371-en. Accessed Sep 12, 2024.","DOI":"10.1787\/9789264185371-en"},{"key":"28","doi-asserted-by":"crossref","unstructured":"Perkins, R.B., Hall, J.E. and Martin, K.A. (2001): Aetiology, previous menstrual function and patterns of neuro-endocrine disturbance as prognostic indicators in hypothalamic amenorrhoea. Hum. Reprod., <b>16<\/b>, 2198-2205.","DOI":"10.1093\/humrep\/16.10.2198"},{"key":"29","doi-asserted-by":"crossref","unstructured":"Rivier, C. and Rivest, S. (1991): Effect of stress on the activity of the hypothalamic-pituitary-gonadal axis: peripheral and central mechanisms. Biol. Reprod., <b>45<\/b>, 523-532.","DOI":"10.1095\/biolreprod45.4.523"},{"key":"30","doi-asserted-by":"crossref","unstructured":"Shah, V., Patel, A., Bambharoliya, P. and Patadia, J. (2021): Sexual Maturity in Adolescents Suffering from Sickle Cell Disease: A Cross-sectional Study. J. Clin. Diagn. Res., <b>15<\/b>, SC01-SC04.","DOI":"10.7860\/JCDR\/2021\/47287.14981"},{"key":"31","doi-asserted-by":"crossref","unstructured":"Shaw, S., Ghosh, D., Kumar, U., Panjwani, U. and Kumar, B. (2018): Impact of high altitude on key determinants of female reproductive health: a review. Int. J. Biometeorol., <b>62<\/b>, 2045-2055.","DOI":"10.1007\/s00484-018-1609-0"},{"key":"32","doi-asserted-by":"crossref","unstructured":"Sisk, C.L. and Zehr, J.L. (2005): Pubertal hormones organize the adolescent brain and behavior. Front. Neuroendocrinol., <b>26<\/b>, 163-174.","DOI":"10.1016\/j.yfrne.2005.10.003"},{"key":"33","doi-asserted-by":"crossref","unstructured":"Smith, S.S., Neuringer, M. and Ojeda, S.R. (1989): Essential fatty acid deficiency delays the onset of puberty in the female rat. Endocrinology, <b>125<\/b>, 1650-1659.","DOI":"10.1210\/endo-125-3-1650"},{"key":"34","doi-asserted-by":"crossref","unstructured":"Stump, D.G., O\u2019Connor, J.C., Lewis, J.M. and Marty, M.S. (2014): Key lessons from performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 male and female pubertal assays. Birth Defects Res. B Dev. Reprod. Toxicol., <b>101<\/b>, 43-62.","DOI":"10.1002\/bdrb.21097"},{"key":"35","doi-asserted-by":"crossref","unstructured":"Terrizzi, A.R., Martinez, M.P. and Fernandez-Solari, J. (2021): Altered production of reproductive neuropeptides in rats subjected to chronic intermittent hypoxia. J. Integr. Neurosci., <b>20<\/b>, 651-657.","DOI":"10.31083\/j.jin2003069"},{"key":"36","unstructured":"U.S. EPA. (1998a): Health Effects Test Guidelines: OPPTS 870.3800 Reproduction and Fertility Effects. Office of Prevention, Pesticides and Toxic Substances, Office of Pesticide Programs Health Effects Division, Washington DC. https:\/\/nepis.epa.gov\/Exe\/ZyPURL.cgi?Dockey=P100HZEN.txt. Accessed Sep 12, 2024."},{"key":"37","unstructured":"U.S. EPA. (1998b): Health Effects Test Guidelines: OPPTS 870.6300 Developmental Neurotoxicity Study. Office of Prevention, Pesticides and Toxic Substances, Office of Pesticide Programs Health Effects Division, Washington DC. https:\/\/nepis.epa.gov\/Exe\/ZyPURL.cgi?Dockey=P100IRWO.txt. Accessed Sep 12, 2024."},{"key":"38","unstructured":"U.S. EPA. (2009a): Endocrine Disruptor Screening Program Test Guidelines - OPPTS 890.1450: Pubertal Development and Thyroid Function in Intact Juvenile\/Peripubertal Female Rats. Office of Prevention, Pesticides and Toxic Substances, Office of Pesticide Programs Health Effects Division, Washington DC. https:\/\/nepis.epa.gov\/Exe\/ZyPURL.cgi?Dockey=P100SHJX.txt. Accessed Sep 12, 2024."},{"key":"39","unstructured":"U.S. EPA. (2009b): Endocrine Disruptor Screening Program Test Guidelines - OPPTS 890.1500: Pubertal Development and Thyroid Function in Intact Juvenile\/Peripubertal Male Rats. Office of Prevention, Pesticides and Toxic Substances, Office of Pesticide Programs Health Effects Division, Washington DC. https:\/\/nepis.epa.gov\/Exe\/ZyPURL.cgi?Dockey=P100SHKS.txt. Accessed Sep 12, 2024."},{"key":"40","doi-asserted-by":"crossref","unstructured":"Uenoyama, Y., Inoue, N., Nakamura, S. and Tsukamura, H. (2019): Central Mechanism Controlling Pubertal Onset in Mammals: A Triggering Role of Kisspeptin. Front. Endocrinol. (Lausanne), <b>10<\/b>, 312.","DOI":"10.3389\/fendo.2019.00312"},{"key":"41","unstructured":"WHO\/International Programme on Chemical Safety. (2002): Global assessment on the State-of-the-Science of Endocrine Disruptors. World Health Organization, Geneva. https:\/\/iris.who.int\/handle\/10665\/67357. Accessed Sep 12, 2024."},{"key":"42","unstructured":"WHO\/Regional Office for South-East Asia. (2011): Prevention of iron deficiency anaemia in adolescents. WHO Regional Office for South-East Asia, New Delhi. https:\/\/iris.who.int\/handle\/ 10665\/205656. Accessed Sep 12, 2024."}],"container-title":["The Journal of Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jts\/50\/2\/50_83\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T04:22:57Z","timestamp":1738383777000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jts\/50\/2\/50_83\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2131\/jts.50.83","relation":{},"ISSN":["0388-1350","1880-3989"],"issn-type":[{"type":"print","value":"0388-1350"},{"type":"electronic","value":"1880-3989"}],"subject":[],"published":{"date-parts":[[2025]]}}}