{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T12:08:39Z","timestamp":1783080519415,"version":"3.54.6"},"reference-count":0,"publisher":"Universiti Sains Malaysia","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MJMS"],"abstract":"<jats:p>Background: Transsphenoidal surgery (TSS) is an increasing preferred treatment for sella lesions. In a university teaching hospital, the novel endoscopic TSS was adopted with ongoing resident teaching. We evaluated a single institutional series of preliminary comparisons of transseptal microscopic with endoscopic TSS. Methods: A retrospective data analysis included 37 patients and 19 patients who underwent microscopic and endoscopic TSS, respectively. The demographic characteristics of the patients, intra-operative analyses, morbidity, mortality and visual assessments were included in this analysis. Results: The study included 31 men and 25 women, and median age at surgery was 49 years old (range 14\u201370 years old). There were no differences between the rates of cerebrospinal fluid (CSF) fistula, sinus complications, anterior pituitary hormone deficiency and diabetes insipidus between the groups. Total length of stay and intensive care unit stay were similar between the groups. Patients who underwent endoscopic TSS were at significantly increased risk of epistaxis (P = 0.010), respiratory event (P = 0.014) and post-operative visual deterioration prior to discharge (P = 0.032). Conclusion: Endoscopic TSS is a promising procedure that allows sufficient visualisation of the surgical field and adequate tumour removal. It is comparable to microscopic TSS but has a higher complication rate notably due to steep learning curve required to gain the expertise.<\/jats:p>","DOI":"10.21315\/mjms2022.29.1.7","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T05:53:31Z","timestamp":1645768411000},"page":"62-75","source":"Crossref","is-referenced-by-count":1,"title":["Preliminary Comparison of Transseptal Microscopic Versus Endoscopic Transsphenoidal Surgery in a University Teaching Hospital"],"prefix":"10.21315","volume":"29","author":[{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaitun","family":"Zakaria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Brain and Behaviour Cluster, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zamzuri","family":"Idris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Brain and Behaviour Cluster, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jafri Malin","family":"Abdullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Brain and Behaviour Cluster, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baharudin","family":"Abdullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Rahman Izaini","family":"Ghani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Brain and Behaviour Cluster, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8963","published-online":{"date-parts":[[2022,2,23]]},"container-title":["Malaysian Journal of Medical Sciences"],"original-title":[],"deposited":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T05:53:40Z","timestamp":1645768420000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.mjms.usm.my\/MJMS29012022\/MJMS29012022_7.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,23]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,2,23]]}},"URL":"https:\/\/doi.org\/10.21315\/mjms2022.29.1.7","relation":{},"ISSN":["1394-195X","2180-4303"],"issn-type":[{"value":"1394-195X","type":"print"},{"value":"2180-4303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,23]]}}}