{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:15:27Z","timestamp":1761707727780},"reference-count":4,"publisher":"Japanese Society for the Study of Xenobiotics","issue":"3","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Metabolism and Pharmacokinetics"],"published-print":{"date-parts":[[2004]]},"DOI":"10.2133\/dmpk.19.236","type":"journal-article","created":{"date-parts":[[2004,11,16]],"date-time":"2004-11-16T09:43:55Z","timestamp":1100598235000},"page":"236-238","source":"Crossref","is-referenced-by-count":22,"title":["A Novel Single Nucleotide Polymorphism (SNP) of the CYP2C19 Gene in a Japanese Subject with Lowered Capacity of Mephobarbital 4\u2032-Hydroxylation"],"prefix":"10.2133","volume":"19","author":[{"given":"Jun","family":"Morita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuko","family":"Wanibuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyuki","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Irie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ishizaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kan","family":"Chiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"900","reference":[{"key":"10.2133\/dmpk.19.236_bb0005","first-page":"36","article-title":"Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by human liver microsomes","volume":"29","author":"Kobayashi","year":"2001","journal-title":"Drug Metab. Dispos."},{"key":"10.2133\/dmpk.19.236_bb0010","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1080\/004982598239236","article-title":"The CYP2 family: models, mutants and interactions","volume":"7","author":"Lewis","year":"1998","journal-title":"Xenobiotica"},{"key":"10.2133\/dmpk.19.236_bb0015","first-page":"594","article-title":"Identification of a new defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese","volume":"46","author":"de Morais","year":"1994","journal-title":"Mol. Pharmacol."},{"key":"10.2133\/dmpk.19.236_bb0020","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0009-9236(96)90214-3","article-title":"Genotyping of S-mephenytoin 4\u2032-hydroxylation in an extended Japanese population","volume":"60","author":"Kubota","year":"1996","journal-title":"Clin. Pharmacol. Ther."}],"container-title":["Drug Metabolism and Pharmacokinetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1347436715308235?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1347436715308235?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T08:37:04Z","timestamp":1545467824000},"score":1,"resource":{"primary":{"URL":"http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1347436715308235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004]]}},"alternative-id":["S1347436715308235"],"URL":"https:\/\/doi.org\/10.2133\/dmpk.19.236","relation":{},"ISSN":["1347-4367"],"issn-type":[{"value":"1347-4367","type":"print"}],"subject":[],"published":{"date-parts":[[2004]]}}}