{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:44:10Z","timestamp":1792215850366,"version":"4.4.0"},"reference-count":54,"publisher":"Japan Poultry Science Association","issue":"0","funder":[{"name":"Key Research and Achievement Transformation Project of the Inner Mongolia Autonomous Region","award":["2023YFDZ0014"],"award-info":[{"award-number":["2023YFDZ0014"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Poult. Sci.","Jpn. Poult. Sci."],"published-print":{"date-parts":[[2026]]},"DOI":"10.2141\/jpsa.2026023","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T22:13:29Z","timestamp":1791584009000},"page":"n\/a","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Three <i>Artemisia<\/i> Extracts and Their Combinations on the Gut Barrier Function and Transcriptomic Regulation of the Jejunum in Laying Hens"],"prefix":"10.2141","volume":"63","author":[{"given":"Yuechen","family":"Liu","sequence":"first","affiliation":[{"name":"College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Jin","sequence":"additional","affiliation":[{"name":"College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Xing","sequence":"additional","affiliation":[{"name":"College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanqiong","family":"Zhou","sequence":"additional","affiliation":[{"name":"College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengsheng","family":"Sun","sequence":"additional","affiliation":[{"name":"Animal-Centered Environments Group, Department of Biosystems and Engineering, Swedish University of Agricultural Sciences, P.O. Box 190, 234 22, Lomma, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binlin","family":"Shi","sequence":"additional","affiliation":[{"name":"College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"908","reference":[{"key":"1","doi-asserted-by":"publisher","unstructured":"[1] Luo Q, Yang L, Tumenjargal B, Liu S, Ma J, Ning J, Yun Z, Zhang X, Wu Y, Lu Y, Wu X, Wang L, Demberel S andLiu D. Effect of composite yeast culture on the jejunal barrier function, inflammatory response, and microbial community structure of laying hens during the late stage of egg production. Front Vet Sci, 11: 1524726. 2024. PMID:39744721, https:\/\/doi.org\/10.3389\/fvets.2024.1524726","DOI":"10.3389\/fvets.2024.1524726"},{"key":"2","doi-asserted-by":"publisher","unstructured":"[2] Zhao Y, Si S, Ren Y, Wu X, Zhang Z, Tian Y, Li J, Li Y, Hou M, Yao X, Xu Z, Jiang R, Kang X, Gong Y, Li Q andTian Y. Marine red yeast supplementation improves laying performance by regulating small intestinal homeostasis in aging chickens. Anim Nutr, 18: 177\u2013190. 2024. PMID:39263442, https:\/\/doi.org\/10.1016\/j.aninu.2024.04.022","DOI":"10.1016\/j.aninu.2024.04.022"},{"key":"3","doi-asserted-by":"publisher","unstructured":"[3] Li Z, Wu H, Fu J, Mushtaq M, Khan M, Liu Y, Azeem Z, Shi H, He Y, Zhang R, Rahman MAU, Kang J, Ge C andWang K. Eggshell quality traits and transcriptome gene screening between Yunnong and Jingfen chicken breeds. Biology (Basel), 13: 1048. 2024. PMID:39765715, https:\/\/doi.org\/10.3390\/biology13121048","DOI":"10.3390\/biology13121048"},{"key":"4","doi-asserted-by":"publisher","unstructured":"[4] Zhang T, Chen Y, Wen J, Jia Y, Wang L, Lv X, Yang W, Qu C, Li H, Wang H, Qu L andNing Z. Transcriptomic analysis of laying hens revealed the role of aging-related genes during forced molting. Genes (Basel), 12: 1767. 2021. PMID:34828373, https:\/\/doi.org\/10.3390\/genes12111767","DOI":"10.3390\/genes12111767"},{"key":"5","doi-asserted-by":"publisher","unstructured":"[5] Kogut MH andArsenault RJ. Editorial: Gut health: The new paradigm in food animal production. Front Vet Sci, 3: 71. 2016. PMID:27630994, https:\/\/doi.org\/10.3389\/fvets.2016.00071","DOI":"10.3389\/fvets.2016.00071"},{"key":"6","doi-asserted-by":"publisher","unstructured":"[6] Ducatelle R, Goossens E, De Meyer F, Eeckhaut V, Antonissen G, Haesebrouck F andVan Immerseel F. Biomarkers for monitoring intestinal health in poultry: present status and future perspectives. Vet Res, 49: 43. 2018. PMID:29739469, https:\/\/doi.org\/10.1186\/s13567-018-0538-6","DOI":"10.1186\/s13567-018-0538-6"},{"key":"7","doi-asserted-by":"publisher","unstructured":"[7] Mishra B andJha R. Oxidative stress in the poultry gut: Potential challenges and interventions. Front Vet Sci, 6: 60. 2019. PMID:30886854, https:\/\/doi.org\/10.3389\/fvets.2019.00060","DOI":"10.3389\/fvets.2019.00060"},{"key":"8","doi-asserted-by":"publisher","unstructured":"[8] Gadde U, Kim WH, Oh ST andLillehoj HS. Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review. Anim Health Res Rev, 18: 26\u201345. 2017. PMID:28485263, https:\/\/doi.org\/10.1017\/S1466252316000207","DOI":"10.1017\/S1466252316000207"},{"key":"9","doi-asserted-by":"publisher","unstructured":"[9] Ji Y, Liu X, Lv H, Guo Y andNie W. Effects of lonicerae flos and turmeric extracts on growth performance and intestinal health of yellow-feathered broilers. Poult Sci, 103: 103488. 2024. PMID:38335669, https:\/\/doi.org\/10.1016\/j.psj.2024.103488","DOI":"10.1016\/j.psj.2024.103488"},{"key":"10","doi-asserted-by":"publisher","unstructured":"[10] Zhao F, Shi B, Sun D, Chen H, Tong M, Zhang P, Guo X andYan S. Effects of dietary supplementation of Artemisia argyi aqueous extract on antioxidant indexes of small intestine in broilers. Anim Nutr, 2: 198\u2013203. 2016. PMID:29767092, https:\/\/doi.org\/10.1016\/j.aninu.2016.06.006","DOI":"10.1016\/j.aninu.2016.06.006"},{"key":"11","doi-asserted-by":"publisher","unstructured":"[11] Bisht D, Kumar D, Kumar D, Dua K andChellappan DK. Phytochemistry and pharmacological activity of the genus artemisia. Arch Pharm Res, 44: 439\u2013474. 2021. PMID:33893998, https:\/\/doi.org\/10.1007\/s12272-021-01328-4","DOI":"10.1007\/s12272-021-01328-4"},{"key":"12","doi-asserted-by":"publisher","unstructured":"[12] Shi L, Guo Y, Cheng Y, Xing Y, Guo S, Zhang L, Xu Y, Jin X, Yan S andShi B. An Artemisia ordosica extract: effects on growth performance, immune, and inflammatory response in lipopolysaccharide-challenged broilers. Front Vet Sci, 9: 980690. 2022. PMID:36157186, https:\/\/doi.org\/10.3389\/fvets.2022.980690","DOI":"10.3389\/fvets.2022.980690"},{"key":"13","doi-asserted-by":"publisher","unstructured":"[13] Jiang M, Zhang X, Jin X, Shi B, Xu Y andWang Z. Relieving effect of Artemisia ordosica Krasch extract on DSS-induced colitis by regulating immunity, antioxidant function, gut microbiota, and bile acid metabolism in mice. Antioxidants, 14: 45. 2025. PMID:39857378, https:\/\/doi.org\/10.3390\/antiox14010045","DOI":"10.3390\/antiox14010045"},{"key":"14","doi-asserted-by":"publisher","unstructured":"[14] Shinyuy LM, Loe GE, Jansen O, Mamede L, Ledoux A, Noukimi SF, Abenwie SN, Ghogomu SM, Souopgui J, Robert A, Demeyer K andFrederich M. Secondary metabolites isolated from Artemisia afra and Artemisia annua and their anti-malarial, anti-inflammatory and immunomodulating properties\u2014Pharmacokinetics and pharmacodynamics: A review. Metabolites, 13: 613. 2023. PMID:37233654, https:\/\/doi.org\/10.3390\/metabo13050613","DOI":"10.3390\/metabo13050613"},{"key":"15","doi-asserted-by":"publisher","unstructured":"[15] Olennikov DN, Chirikova NK, Kashchenko NI, Nikolaev VM, Kim SW andVennos C. Bioactive phenolics of the genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS\/MS profile of the Siberian species and their inhibitory potential against \u03b1-amylase and \u03b1-glucosidase. Front Pharmacol, 9: 756. 2018. PMID:30050443, https:\/\/doi.org\/10.3389\/fphar.2018.00756","DOI":"10.3389\/fphar.2018.00756"},{"key":"16","doi-asserted-by":"publisher","unstructured":"[16] Xing Y, Wu Y, Mao C, Sun D, Guo S, Xu Y, Jin X, Yan S andShi B. Water extract of Artemisia ordosica enhances antioxidant capability and immune response without affecting growth performance in weanling piglets. J Anim Physiol Anim Nutr (Berl), 103: 1848\u20131856. 2019. PMID:31410913, https:\/\/doi.org\/10.1111\/jpn.13171","DOI":"10.1111\/jpn.13171"},{"key":"17","doi-asserted-by":"publisher","unstructured":"[17] Guo S, Ma J, Xing Y, Xu Y, Jin X, Yan S andShi B. Artemisia annua L. aqueous extract as an alternative to antibiotics improving growth performance and antioxidant function in broilers. Ital J Anim Sci, 19: 399\u2013409. 2020. https:\/\/doi.org\/10.1080\/1828051X.2020.1745696","DOI":"10.1080\/1828051X.2020.1745696"},{"key":"18","doi-asserted-by":"publisher","unstructured":"[18] Gao R, Du J, Gang G, Jin X, Xing Y, Xu Y, Hong L, Yan S andShi B. Effects of Artemisia argyi aqueous extract on rumen fermentation parameters and microbiota in lambs. Fermentation (Basel), 11: 53. 2025. https:\/\/doi.org\/10.3390\/fermentation11020053","DOI":"10.3390\/fermentation11020053"},{"key":"19","unstructured":"[19] Jiang D. Effects of Artemisia argyi aqueous extract on laying performance, antioxidant capacity and immune function in laying hens. Master\u2019s Thesis, Inner Mongolia Agricultural University. Hohhot, China, 2025. (in Chinese)"},{"key":"20","doi-asserted-by":"publisher","unstructured":"[20] Wang Q, Wang L, Li L, Sun M, Li P, Yu Y, Zhang Y, Xu Z, Gao P, Ma J andLiu X. Effects of dietary supplementation of fermented Artemisia argyi on growth performance, slaughter performance, and meat quality in broilers. Poult Sci, 103: 103545. 2024. PMID:38387294, https:\/\/doi.org\/10.1016\/j.psj.2024.103545","DOI":"10.1016\/j.psj.2024.103545"},{"key":"21","doi-asserted-by":"publisher","unstructured":"[21] Oni AI andOke OE. Gut health modulation through phytogenics in poultry: mechanisms, benefits, and applications. Front Vet Sci, 12: 1616734. 2025. PMID:40909941, https:\/\/doi.org\/10.3389\/fvets.2025.1616734","DOI":"10.3389\/fvets.2025.1616734"},{"key":"22","doi-asserted-by":"publisher","unstructured":"[22] Wang Y, Liu XJ, Chen JB, Cao JP, Li X andSun CD. Citrus flavonoids and their antioxidant evaluation. Crit Rev Food Sci Nutr, 62: 3833\u20133854. 2022. PMID:33435726, https:\/\/doi.org\/10.1080\/10408398.2020.1870035","DOI":"10.1080\/10408398.2020.1870035"},{"key":"23","doi-asserted-by":"publisher","unstructured":"[23] Baggieri M, Gioacchini S, Borgonovo G, Catinella G, Marchi A, Picone P, Vasto S, Fioravanti R, Bucci P, Kojouri M, Giuseppetti R, D\u2019Ugo E, Ubaldi F, Dallavalle S, Nuzzo D, Pinto A andMagurano F. Antiviral, virucidal and antioxidant properties of Artemisia annua against SARS-CoV-2. Biomed Pharmacother, 168: 115682. 2023. PMID:37832410, https:\/\/doi.org\/10.1016\/j.biopha.2023.115682","DOI":"10.1016\/j.biopha.2023.115682"},{"key":"24","doi-asserted-by":"publisher","unstructured":"[24] Ni Z, Nie A, Imran M, Sun Z, Zhang B, Wang Z, Qi Y andLi C. Dietary fermented Artemisia argyi enhances growth performance, hepatic antioxidant activity, and intestinal health in Hongyu roosters. Poult Sci, 104: 105900. 2025. PMID:41046716, https:\/\/doi.org\/10.1016\/j.psj.2025.105900","DOI":"10.1016\/j.psj.2025.105900"},{"key":"25","doi-asserted-by":"publisher","unstructured":"[25] Guo S, Ma J, Xing Y, Shi L, Zhang L, Xu Y, Jin X, Yan S andShi B. Artemisia annua L. aqueous extract promotes intestine immunity and antioxidant function in broilers. Front Vet Sci, 9: 934021. 2022. PMID:35873687, https:\/\/doi.org\/10.3389\/fvets.2022.934021","DOI":"10.3389\/fvets.2022.934021"},{"key":"26","doi-asserted-by":"publisher","unstructured":"[26] Xing Y, Zheng Y, Chen L, Xu Y, Jin X, Hong L, Yan S andShi B. Artemisia ordosica polysaccharides enhance antioxidant capacity of peripheral blood lymphocytes in poultry through Nrf2\/Keap1 and TLR4\/NF-\u03baB signal pathway. Antioxidants, 13: 1308. 2024. PMID:39594450, https:\/\/doi.org\/10.3390\/antiox13111308","DOI":"10.3390\/antiox13111308"},{"key":"27","doi-asserted-by":"publisher","unstructured":"[27] Shi L, Jin X, Xu Y, Xing Y, Yan S, Guo Y, Cheng Y andShi B. Effects of total flavonoids of Artemisia ordosica on growth performance, oxidative stress, and antioxidant status of lipopolysaccharide-challenged broilers. Antioxidants, 11: 1985. 2022. PMID:36290707, https:\/\/doi.org\/10.3390\/antiox11101985","DOI":"10.3390\/antiox11101985"},{"key":"28","doi-asserted-by":"publisher","unstructured":"[28] Medica AJ, Aitken RJ, Nicolson GL, Sheridan AR, Swegen A, De Iuliis GN andGibb Z. Glycerophospholipids protect stallion spermatozoa from oxidative damage in vitro. Reprod Fertil, 2: 199\u2013209. 2021. PMID:35118390, https:\/\/doi.org\/10.1530\/RAF-21-0028","DOI":"10.1530\/RAF-21-0028"},{"key":"29","doi-asserted-by":"publisher","unstructured":"[29] Lai X, Wu A, Yu B, Yan H, Luo J, Zheng P, Yu J andChen D. Retinoic acid alleviates rotavirus-induced intestinal damage by regulating redox homeostasis and autophagic flux in piglets. Anim Nutr, 16: 409\u2013421. 2024. PMID:38371474, https:\/\/doi.org\/10.1016\/j.aninu.2023.12.007","DOI":"10.1016\/j.aninu.2023.12.007"},{"key":"30","doi-asserted-by":"publisher","unstructured":"[30] Reddy RC andStandiford TJ. Nrf2 and PPAR\u03b3: PPARtnering against oxidant-induced lung injury. Am J Respir Crit Care Med, 182: 134\u2013135. 2010. PMID:20634499, https:\/\/doi.org\/10.1164\/rccm.201004-0457ED","DOI":"10.1164\/rccm.201004-0457ED"},{"key":"31","doi-asserted-by":"publisher","unstructured":"[31] Du H, Xing Y, Xu Y, Jin X, Yan S andShi B. Dietary Artemisia ordosica polysaccharide enhances spleen and intestinal immune response of broiler chickens. Biology (Basel), 12: 1390. 2023. PMID:37997990, https:\/\/doi.org\/10.3390\/biology12111390","DOI":"10.3390\/biology12111390"},{"key":"32","doi-asserted-by":"publisher","unstructured":"[32] Kuhn KA, Schulz HM, Regner EH, Severs EL, Hendrickson JD, Mehta G, Whitney AK, Ir D, Ohri N, Robertson CE, Frank DN, Campbell EL andColgan SP. Bacteroidales recruit IL-6-producing intraepithelial lymphocytes in the colon to promote barrier integrity. Mucosal Immunol, 11: 357\u2013368. 2018. PMID:28812548, https:\/\/doi.org\/10.1038\/mi.2017.55","DOI":"10.1038\/mi.2017.55"},{"key":"33","doi-asserted-by":"publisher","unstructured":"[33] Jung Y, Wen T, Mingler MK, Caldwell JM, Wang YH, Chaplin DD, Lee EH, Jang MH, Woo SY, Seoh JY, Miyasaka M andRothenberg ME. IL-1\u03b2 in eosinophil-mediated small intestinal homeostasis and IgA production. Mucosal Immunol, 8: 930\u2013942. 2015. PMID:25563499, https:\/\/doi.org\/10.1038\/mi.2014.123","DOI":"10.1038\/mi.2014.123"},{"key":"34","doi-asserted-by":"publisher","unstructured":"[34] Bamias G, Arseneau KO andCominelli F. Cytokines and mucosal immunity. Curr Opin Gastroenterol, 30: 547\u2013552. 2014. PMID:25203451, https:\/\/doi.org\/10.1097\/MOG.0000000000000118","DOI":"10.1097\/MOG.0000000000000118"},{"key":"35","doi-asserted-by":"publisher","unstructured":"[35] Mantis NJ, Rol N andCorth\u00e9sy B. Secretory IgA\u2019s complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunol, 4: 603\u2013611. 2011. PMID:21975936, https:\/\/doi.org\/10.1038\/mi.2011.41","DOI":"10.1038\/mi.2011.41"},{"key":"36","doi-asserted-by":"publisher","unstructured":"[36] Circu ML andAw TY. Intestinal redox biology and oxidative stress. Semin Cell Dev Biol, 23: 729\u2013737. 2012. PMID:22484611, https:\/\/doi.org\/10.1016\/j.semcdb.2012.03.014","DOI":"10.1016\/j.semcdb.2012.03.014"},{"key":"37","doi-asserted-by":"publisher","unstructured":"[37] Qiu K, Li C, Wang J, Qi G, Gao J, Zhang H andWu S. Effects of dietary supplementation with Bacillus subtilis, as an alternative to antibiotics, on growth performance, serum immunity, and intestinal health in broiler chickens. Front Nutr, 8: 786878. 2021. PMID:34917643, https:\/\/doi.org\/10.3389\/fnut.2021.786878","DOI":"10.3389\/fnut.2021.786878"},{"key":"38","doi-asserted-by":"publisher","unstructured":"[38] Song ZH, Cheng K, Zheng XC, Ahmad H, Zhang LL andWang T. Effects of dietary supplementation with enzymatically treated Artemisia annua on growth performance, intestinal morphology, digestive enzyme activities, immunity, and antioxidant capacity of heat-stressed broilers. Poult Sci, 97: 430\u2013437. 2018. PMID:29077887, https:\/\/doi.org\/10.3382\/ps\/pex312","DOI":"10.3382\/ps\/pex312"},{"key":"39","doi-asserted-by":"publisher","unstructured":"[39] Zhang L, Xing Y, Shi L, Guo S, Jin X, Xu Y, Yan S andShi B. The effects of dietary supplementation of Artemisia argyi polysaccharide on immune and antioxidative functions in broilers. J Appl Anim Res, 50: 587\u2013597. 2022. https:\/\/doi.org\/10.1080\/09712119.2022.2119982","DOI":"10.1080\/09712119.2022.2119982"},{"key":"40","doi-asserted-by":"publisher","unstructured":"[40] Xing Y, Zheng Y, Yang S, Zhang L, Guo S, Shi L, Xu Y, Jin X, Yan S andShi B. Artemisia ordosica polysaccharide ameliorated LPS-induced growth inhibition and intestinal injury in broilers through enhancing immune-regulation and antioxidant capacity. J Nutr Biochem, 115: 109284. 2023. PMID:36828238, https:\/\/doi.org\/10.1016\/j.jnutbio.2023.109284","DOI":"10.1016\/j.jnutbio.2023.109284"},{"key":"41","doi-asserted-by":"publisher","unstructured":"[41] Wang Z, Li J, Wang Y, Wang L, Yin Y, Yin L, Yang H andYin Y. Dietary vitamin A affects growth performance, intestinal development, and functions in weaned piglets by affecting intestinal stem cells. J Anim Sci, 98: skaa020. 2020. PMID:31955210, https:\/\/doi.org\/10.1093\/jas\/skaa020","DOI":"10.1093\/jas\/skaa020"},{"key":"42","doi-asserted-by":"publisher","unstructured":"[42] Harayama T andRiezman H. Understanding the diversity of membrane lipid composition. Nat Rev Mol Cell Biol, 19: 281\u2013296. 2018. PMID:29410529, https:\/\/doi.org\/10.1038\/nrm.2017.138","DOI":"10.1038\/nrm.2017.138"},{"key":"43","doi-asserted-by":"publisher","unstructured":"[43] Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol, 9: 799\u2013809. 2009. PMID:19855405, https:\/\/doi.org\/10.1038\/nri2653","DOI":"10.1038\/nri2653"},{"key":"44","doi-asserted-by":"publisher","unstructured":"[44] Chelakkot C, Ghim J andRyu SH. Mechanisms regulating intestinal barrier integrity and its pathological implications. Exp Mol Med, 50: 1\u20139. 2018. PMID:30115904, https:\/\/doi.org\/10.1038\/s12276-018-0126-x","DOI":"10.1038\/s12276-018-0126-x"},{"key":"45","doi-asserted-by":"publisher","unstructured":"[45] Al-Sadi R, Boivin M andMa T. Mechanism of cytokine modulation of epithelial tight junction barrier. Front Biosci, 14: 2765\u20132778. 2009. PMID:19273235, https:\/\/doi.org\/10.2741\/3413","DOI":"10.2741\/3413"},{"key":"46","doi-asserted-by":"crossref","unstructured":"[46] Lin PY, Stern A, Peng HH, Chen JH andYang HC. Redox and metabolic regulation of intestinal barrier function and associated disorders. Int J Mol Sci, 23: 14463. 2022. PMID:36430939, https:\/\/doi.org\/10.3390\/ijms232214463","DOI":"10.3390\/ijms232214463"},{"key":"47","doi-asserted-by":"publisher","unstructured":"[47] \u00c7akmaz R, B\u00fcy\u00fcka\u015f\u0131k O, Kahramansoy N, Erkol H, \u00c7\u00f6l C, Boran \u00c7 andBu\u011fdayc\u0131 G. A combination of plasma DAO and citrulline levels as a potential marker for acute mesenteric ischemia. Libyan J Med, 8: 20596. 2013. PMID:23534825, https:\/\/doi.org\/10.3402\/ljm.v8i0.20596","DOI":"10.3402\/ljm.v8i0.20596"},{"key":"48","doi-asserted-by":"publisher","unstructured":"[48] Guo S, Shi B, Xing Y, Xu Y, Jin X, Hong L, Zhang S, Qiao M andYan S. Artemisia annua L. polysaccharide improves the growth performance and intestinal barrier function of broilers challenged with Escherichia coli. Front Microbiol, 15: 1390815. 2024. PMID:38746748, https:\/\/doi.org\/10.3389\/fmicb.2024.1390815","DOI":"10.3389\/fmicb.2024.1390815"},{"key":"49","doi-asserted-by":"publisher","unstructured":"[49] Zhang P, Yang D, Xiao J, Hong W, Sun H, Xie Q andZeng C. Artemisia argyi polysaccharide alleviates osmotic diarrhea by enhancing intestinal barrier protection and anti-inflammation. Int J Biol Macromol, 282: 136779. 2024. PMID:39442837, https:\/\/doi.org\/10.1016\/j.ijbiomac.2024.136779","DOI":"10.1016\/j.ijbiomac.2024.136779"},{"key":"50","doi-asserted-by":"publisher","unstructured":"[50] Gattazzo F, Urciuolo A andBonaldo P. Extracellular matrix: A dynamic microenvironment for stem cell niche. Biochim Biophys Acta, Gen Subj, 1840: 2506\u20132519. 2014. PMID:24418517, https:\/\/doi.org\/10.1016\/j.bbagen.2014.01.010","DOI":"10.1016\/j.bbagen.2014.01.010"},{"key":"51","doi-asserted-by":"publisher","unstructured":"[51] Hartsock A andNelson WJ. Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta Biomembr, 1778: 660\u2013669. 2008. PMID:17854762, https:\/\/doi.org\/10.1016\/j.bbamem.2007.07.012","DOI":"10.1016\/j.bbamem.2007.07.012"},{"key":"52","doi-asserted-by":"publisher","unstructured":"[52] Li Q, Xia Z, Wu Y, Ma Y, Zhang D, Wang S, Fan J, Xu P, Li X, Bai L, Zhou X andXue M. Lysophospholipid acyltransferase\u2010mediated formation of saturated glycerophospholipids maintained cell membrane integrity for hypoxic adaptation. FEBS J, 291: 3191\u20133210. 2024. PMID:38602252, https:\/\/doi.org\/10.1111\/febs.17132","DOI":"10.1111\/febs.17132"},{"key":"53","doi-asserted-by":"crossref","unstructured":"[53] Hosseinzadeh L, Malekshahi A, Ahmadi F, Emami SA, Hajialyani M andMojarrab M. The protective effect of different extracts of three Artemisia species against H2O2-induced oxidative stress and apoptosis in PC12 neuronal cells. Pharmacognosy Res, 10: 64\u201371. 2018. PMID:29568190","DOI":"10.7324\/JAPS.2019.90403"},{"key":"54","doi-asserted-by":"publisher","unstructured":"[54] Hu J, Bai M, Xing Y, Liu J, Xu K, Xiong X, Liu H andYin Y. Artemisia annua residue regulates immunity, antioxidant ability, intestinal barrier function, and microbial structure in weaned piglets. Animals (Basel), 14: 3569. 2024. PMID:39765473, https:\/\/doi.org\/10.3390\/ani14243569","DOI":"10.3390\/ani14243569"}],"container-title":["The Journal of Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jpsa\/63\/0\/63_2026023\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:20:32Z","timestamp":1792214432000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jpsa\/63\/0\/63_2026023\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":54,"journal-issue":{"issue":"0","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.2141\/jpsa.2026023","relation":{},"ISSN":["1346-7395","1349-0486"],"issn-type":[{"value":"1346-7395","type":"print"},{"value":"1349-0486","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"2026023"}}