{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:19:39Z","timestamp":1791231579777,"version":"4.1.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,1]]},"DOI":"10.2146\/ajhp130221","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T20:04:49Z","timestamp":1392667489000},"page":"394-402","source":"Crossref","is-referenced-by-count":104,"title":["Quetiapine for insomnia: A review of the literature"],"prefix":"10.1093","volume":"71","author":[{"given":"Sarah L.","family":"Anderson","sequence":"first","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, and Clinical Pharmacy Specialist, Denver Health Medical Center, Denver, CO."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P.","family":"Vande Griend","sequence":"additional","affiliation":[{"name":"Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"suppl","key":"2019041210505059900_b1-0710394","first-page":"S7","article-title":"Insomnia: definition, prevalence, etiology, and consequences","volume":"3","author":"Roth","year":"2007","journal-title":"J Clin Sleep Med"},{"key":"2019041210505059900_b2-0710394","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1176\/ajp.154.10.1417","article-title":"Prevalence, burden, and treatment of insomnia in primary care","volume":"154","author":"Simon","year":"1997","journal-title":"Am J Psychiatry"},{"key":"2019041210505059900_b3-0710394","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.sleep.2008.04.005","article-title":"Insomnia and its relationship to healthcare utilization, work absenteeism, productivity and accidents","volume":"10","author":"Daley","year":"2009","journal-title":"Sleep Med"},{"key":"2019041210505059900_b4-0710394","first-page":"1","article-title":"The societal costs of insomnia","volume":"7","author":"Wade","year":"2011","journal-title":"Neuropsychiatr Dis Treat"},{"key":"2019041210505059900_b5-0710394","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1001\/archinternmed.2008.610","article-title":"The natural history of insomnia: a population-based 3-year longitudinal study","volume":"169","author":"Morin","year":"2009","journal-title":"Arch Intern Med"},{"key":"2019041210505059900_b6-0710394","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/NSS.S28362","article-title":"An approach to long-term sedative hypnotic use","volume":"4","author":"Shahid","year":"2012","journal-title":"Nat Sci Sleep"},{"key":"2019041210505059900_b7-0710394","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. Highlights to changes from DSM-IV-TR to DSM-5. www.psychiatry.org\/File%20Library\/Practice\/DSM\/DSM-5\/Changes-from-DSM-IV-TR\u2013to-DSM-5.pdf (accessed 2013 Jun 11).","DOI":"10.1176\/appi.focus.11.4.525"},{"issue":"suppl 4","key":"2019041210505059900_b8-0710394","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1016\/S1389-9457(08)70004-2","article-title":"Insomnia and comorbid psychiatric disorders","volume":"8","author":"Riemann","year":"2007","journal-title":"Sleep Med"},{"key":"2019041210505059900_b9-0710394","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1378\/chest.08-1834","article-title":"Update on sleep and psychiatric disorders","volume":"135","author":"Sateia","year":"2009","journal-title":"Chest"},{"key":"2019041210505059900_b10-0710394","volume-title":"Seroquel (quetiapine fumarate) package insert","year":"2012"},{"key":"2019041210505059900_b11-0710394","volume-title":"Seroquel XR (quetiapine fumarate) package insert","year":"2012"},{"key":"2019041210505059900_b12-0710394","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/10401230701866870","article-title":"Patterns of quetiapine use in psychiatric inpatients: an examination of off-label use","volume":"20","author":"Philip","year":"2008","journal-title":"Ann Clin Psychiatry"},{"key":"2019041210505059900_b13-0710394","article-title":"Quetiapine","volume-title":"Drugdex System"},{"key":"2019041210505059900_b14-0710394","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1017\/S1092852900017089","article-title":"Selective histamine H1 antagonism: novel hypnotic and pharmacologic actions challenge classical notions of antihistamines","volume":"13","author":"Stahl","year":"2008","journal-title":"CNS Spectr"},{"key":"2019041210505059900_b15-0710394","doi-asserted-by":"crossref","first-page":"487","DOI":"10.5664\/jcsm.27286","article-title":"Clinical guideline for the evaluation and management of chronic insomnia in adults","volume":"4","author":"Schutte-Rodin","year":"2008","journal-title":"J Clin Sleep Med"},{"key":"2019041210505059900_b16-0710394","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1177\/1078345811421591","article-title":"Guideline, education, and peer comparison to reduce prescriptions of benzodiazepines and low-dose quetiapine in prison","volume":"18","author":"Reeves","year":"2012","journal-title":"J Correct Health Care"},{"key":"2019041210505059900_b17-0710394","unstructured":"Levin A . Concern raised over antipsychotic\u2019s use for sleep problems. http:\/\/psychnews.psychiatryonline.org\/newsArticle.aspx?articleid=116611 (accessed 2013 Apr 4)."},{"key":"2019041210505059900_b18-0710394","unstructured":"Kime P . DoD cracks down on off-label drug use. www.militarytimes.com\/news\/2012\/06\/military-dod-cracks-down-on-off-label-seroquel-use-061412w\/ (accessed 2013 Apr 4)."},{"key":"2019041210505059900_b19-0710394","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1093\/sleep\/27.8.1441","article-title":"Drugs used to treat insomnia in 2002: regulatory-based rather than evidence-based medicine","volume":"27","author":"Walsh","year":"2004","journal-title":"Sleep"},{"key":"2019041210505059900_b20-0710394","unstructured":"Thomson Reuters Micromedex Clinical Evidence Solutions. http:\/\/thomsonreuters.com\/products_services\/healthcare\/healthcare_products\/clinical_deci_support\/micromedex_clinical_evidence_sols\/med_safety_solutions\/red_book (accessed 2013 Apr 4)."},{"key":"2019041210505059900_b21-0710394","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s00213-003-1759-5","article-title":"Sleep-promoting properties of quetiapine in healthy subjects","volume":"174","author":"Cohrs","year":"2004","journal-title":"Psychopharmacology"},{"key":"2019041210505059900_b22-0710394","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00213-007-0968-8","article-title":"Quetiapine in primary insomnia: a pilot study","volume":"196","author":"Wiegand","year":"2008","journal-title":"Psychopharmacology"},{"key":"2019041210505059900_b23-0710394","first-page":"729","article-title":"Quetiapine for primary insomnia: a double blind, randomized controlled trial","volume":"93","author":"Tassniyom","year":"2010","journal-title":"J Med Assoc Thai"},{"key":"2019041210505059900_b24-0710394","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00213-006-0452-x","article-title":"Quetiapine augmentation in treatment-resistant depression: a naturalistic study","volume":"187","author":"\u0160agud","year":"2006","journal-title":"Psychopharmacology"},{"key":"2019041210505059900_b25-0710394","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/YIC.0b013e328301a74c","article-title":"A randomized, double-blind, and placebo-controlled trial of quetiapine augmentation of fluoxetine in major depressive disorder","volume":"23","author":"Garakani","year":"2008","journal-title":"Int Clin Psychopharm"},{"key":"2019041210505059900_b26-0710394","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.jad.2008.06.019","article-title":"Quetiapine monotherapy in the treatment of depressive episodes of bipolar I and II disorder: improvements in quality of life and quality of sleep","volume":"111","author":"Endicott","year":"2008","journal-title":"J Affect Disord"},{"key":"2019041210505059900_b27-0710394","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4088\/JCP.08m04942gre","article-title":"A double-blind, placebo-controlled study of quetiapine and paroxetine as monotherapy in adults with bipolar depression (EMBOLDEN II)","volume":"71","author":"McElroy","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"2019041210505059900_b28-0710394","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/01.wnf.0000174932.82134.e2","article-title":"Quetiapine for insomnia in Parkinson disease: results from an open-label trial","volume":"28","author":"Juri","year":"2005","journal-title":"Clin Neuropharmacol"},{"key":"2019041210505059900_b29-0710394","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1176\/appi.psy.50.2.159","article-title":"Quetiapine for tamoxifen-induced insomnia in women with breast cancer","volume":"50","author":"Pasquini","year":"2009","journal-title":"Psychosomatics"},{"key":"2019041210505059900_b30-0710394","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1080\/10826080802290240","article-title":"Quetiapine in the treatment of sleep disturbances associated with addictive conditions: a retrospective study","volume":"43","author":"Ter\u00e1n","year":"2008","journal-title":"Subst Use Misuse"},{"key":"2019041210505059900_b31-0710394","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00019442-200505000-00006","article-title":"Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults","volume":"13","author":"Yamashita","year":"2005","journal-title":"Am J Geriatr Psychiatry"},{"key":"2019041210505059900_b32-0710394","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1097\/01.jcp.0000239798.59943.77","article-title":"Night locomotor activity and quality of sleep in quetiapine-treated patients with depression","volume":"26","author":"Todder","year":"2006","journal-title":"J Clin Psychopharmacol"},{"key":"2019041210505059900_b33-0710394","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hup.817","article-title":"Effects of adjunctive antidepressant therapy with quetiapine on clinical outcome, quality of sleep and daytime motor activity in patients with treatment-resistant depression","volume":"22","author":"Baune","year":"2007","journal-title":"Hum Psychopharmacol Clin Exp"},{"key":"2019041210505059900_b34-0710394","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s10597-009-9200-0","article-title":"Metabolic consequences of using low-dose quetiapine for insomnia in psychiatric patients","volume":"45","author":"Cates","year":"2009","journal-title":"Community Ment Health J"},{"key":"2019041210505059900_b35-0710394","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1080\/10550490802266185","article-title":"Low-dose quetiapine is not a benign sedative-hypnotic agent","volume":"17","author":"Gugger","year":"2008","journal-title":"Am J Addict"},{"key":"2019041210505059900_b36-0710394","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1345\/aph.1Q697","article-title":"Safety of low doses of quetiapine when used for insomnia","volume":"46","author":"Coe","year":"2012","journal-title":"Ann Pharmacother"},{"key":"2019041210505059900_b37-0710394","doi-asserted-by":"crossref","first-page":"596","DOI":"10.2337\/diacare.27.2.596","article-title":"Consensus development conference on antipsychotic drugs and obesity and diabetes","volume":"27","author":"American Diabetes Association, American Psychiatric Association, American Association of Clinical Endocrinologists, North American Association for the Study of Obesity","year":"2004","journal-title":"Diabetes Care"},{"key":"2019041210505059900_b38-0710394","unstructured":"IMS Institute for Healthcare Informatics. The use of medicines in the United States: review of 2011. www.imshealth.com\/ims\/Global\/Content\/Insights\/IMS%20Institute%20for%20Healthcare%20Informatics\/IHII_Medicines_in_U.S_Report_2011.pdf (accessed 2012 Jun 29)."},{"key":"2019041210505059900_b39-0710394","first-page":"13","article-title":"Is Seroquel developing an illicit reputation for misuse\/abuse?","volume":"7","author":"Sansone","year":"2010","journal-title":"Psychiatry"},{"key":"2019041210505059900_b40-0710394","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1176\/ajp.2007.164.1.173a","article-title":"Intravenous quetiapine-cocaine use (\u201cQ-ball\u201d)","volume":"164","author":"Waters","year":"2007","journal-title":"Am J Psychiatry"},{"key":"2019041210505059900_b41-0710394","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1176\/ajp.2007.164.1.174","article-title":"Quetiapine addiction?","volume":"164","author":"Pinta","year":"2007","journal-title":"Am J Psychiatry"},{"key":"2019041210505059900_b42-0710394","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/009885881103700202","article-title":"Off-label drug use and promotion: balancing public health goals and commercial speech","volume":"37","author":"Kesselheim","year":"2011","journal-title":"Am J Law Med"}],"container-title":["American Journal of Health-System Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ajhp\/article-pdf\/71\/5\/394\/28372273\/ajhp0394.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,15]],"date-time":"2020-08-15T12:48:35Z","timestamp":1597495715000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ajhp\/article\/71\/5\/394\/5111133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,1]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,3,1]]}},"URL":"https:\/\/doi.org\/10.2146\/ajhp130221","relation":{},"ISSN":["1079-2082","1535-2900"],"issn-type":[{"value":"1079-2082","type":"print"},{"value":"1535-2900","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2014,3,1]]},"published":{"date-parts":[[2014,3,1]]}}}