{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T13:04:18Z","timestamp":1776085458718,"version":"3.50.1"},"reference-count":27,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BCTT"],"DOI":"10.2147\/bctt.s569936","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T12:25:13Z","timestamp":1776083113000},"page":"1-14","source":"Crossref","is-referenced-by-count":0,"title":["Single-Cell Profiling Reveals a Treg-Rich, NK Cell-Depleted Immune Microenvironment in Triple-Negative Breast Cancer with High-Glucocorticoid Receptor Expression"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4262-6434","authenticated-orcid":true,"given":"Joshua","family":"Behar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Shiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Dolcen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynda","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"DeVilbiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarite","family":"Matossian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5248-0876","authenticated-orcid":true,"given":"Rita","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Conzen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Lafin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2026,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1038\/nrclinonc.2016.66","volume":"13","author":"Bianchini","year":"2016","journal-title":"Nat Rev Clin Oncol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1056\/NEJMoa1910549","volume":"382","author":"Schmid","year":"2020","journal-title":"New Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/j.cell.2018.08.039","volume":"174","author":"Keren","year":"2018","journal-title":"Cell"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1038\/s41586-019-1876-x","volume":"578","author":"Jackson","year":"2020","journal-title":"Nature"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1016\/j.immuni.2020.08.005","volume":"53","author":"Acharya","year":"2020","journal-title":"Immunity"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"7041","DOI":"10.1038\/s41467-021-27349-7","volume":"12","author":"Deng","year":"2021","journal-title":"Nat Commun"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"7020","DOI":"10.1158\/0008-5472.CAN-13-1290","volume":"73","author":"Skor","year":"2013","journal-title":"Cancer Res"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"6360","DOI":"10.1158\/0008-5472.CAN-11-0362","volume":"71","author":"Pan","year":"2011","journal-title":"Cancer Res"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/s10549-024-07515-3","volume":"209","author":"Matossian","year":"2024","journal-title":"Breast Cancer Res Treat"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e173141","DOI":"10.1172\/JCI173141","volume":"133","author":"Swatler","year":"2023","journal-title":"J Clin Invest"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/nmeth.2869","volume":"11","author":"Geisen","year":"2014","journal-title":"Nature Methods"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/nri.2017.1","volume":"17","author":"Cain","year":"2017","journal-title":"Nat Rev Immunol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"8353","DOI":"10.1038\/s41467-023-43458-x","volume":"14","author":"Janesick","year":"2023","journal-title":"Nat Commun"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"859414","DOI":"10.3389\/fimmu.2022.859414","volume":"13","author":"Le Rochais","year":"2022","journal-title":"Front Immunol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"6813","DOI":"10.1021\/ac901049w","volume":"81","author":"Bandura","year":"2009","journal-title":"Anal Chem"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1002\/cyto.a.23053","volume":"91","author":"Chang","year":"2017","journal-title":"Cytometry Part A"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"3565","DOI":"10.1038\/s41596-023-00881-0","volume":"18","author":"Windhager","year":"2023","journal-title":"Nature Protocols"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1038\/s41587-021-01094-0","volume":"40","author":"Greenwald","year":"2022","journal-title":"Nature Biotechnol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1093\/bioinformatics\/btw777","volume":"33","author":"McCarthy","year":"2017","journal-title":"Bioinformatics"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1038\/s41592-019-0619-0","volume":"16","author":"Korsunsky","year":"2019","journal-title":"Nature Methods"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/s41587-021-01033-z","volume":"40","author":"Dann","year":"2021","journal-title":"Nature Biotechnol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"3671","DOI":"10.1038\/s41467-022-31238-y","volume":"13","author":"Lee","year":"2022","journal-title":"Nat Commun"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02788","volume":"9","author":"Machicote","year":"2018","journal-title":"Front Immunol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1038\/s41591-018-0085-8","volume":"173","author":"Barry","year":"2018","journal-title":"Cell"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/s41586-018-0575-3","volume":"562","author":"Bottcher","year":"2018","journal-title":"Nature"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1016\/j.cell.2017.10.001","volume":"171","author":"McGranahan","year":"2017","journal-title":"Cell"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"101957","DOI":"10.1016\/j.tranon.2024.101957","volume":"45","author":"Snijesh","year":"2024","journal-title":"Transl Oncol"}],"container-title":["Breast Cancer: Targets and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/114004","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/114004","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T12:25:13Z","timestamp":1776083113000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/single-cell-profiling-reveals-a-treg-rich-nk-cell-depleted-immune-micr-peer-reviewed-fulltext-article-BCTT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":27,"URL":"https:\/\/doi.org\/10.2147\/bctt.s569936","relation":{},"ISSN":["1179-1314"],"issn-type":[{"value":"1179-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}