{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T08:40:27Z","timestamp":1737362427340,"version":"3.33.0"},"reference-count":46,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CCID"],"DOI":"10.2147\/ccid.s495773","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T08:10:11Z","timestamp":1737360611000},"page":"191-200","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the Impact of Systemic Inflammatory Regulators on Rosacea Risk: A Bidirectional Mendelian Randomization Analysis"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7807-3494","authenticated-orcid":true,"given":"Qiao","family":"Xue","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lai","family":"Fei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,1]]},"reference":[{"key":"ref1","first-page":"1","volume":"26","author":"Kang","year":"2021","journal-title":"Skin Therapy Lett"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.12968\/hmed.2020.0417","volume":"82","author":"Searle","year":"2021","journal-title":"Br J Hosp Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/j.jaad.2004.01.048","volume":"50","author":"Wilkin","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S36","DOI":"10.1016\/j.jaad.2013.04.042","volume":"69","author":"Vieira","year":"2013","journal-title":"J Am Acad Dermatol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1111\/ceo.13900","volume":"49","author":"Tavassoli","year":"2021","journal-title":"Clin Exp Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1067\/mjd.2002.120625","volume":"46","author":"Wilkin","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1111\/j.1468-3083.2009.03167.x","volume":"23","author":"Korting","year":"2009","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1111\/1346-8138.16329","volume":"49","author":"Liu","year":"2022","journal-title":"J Dermatol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1038\/jidsymp.2011.9","volume":"15","author":"Gerber","year":"2011","journal-title":"J Investig Dermatol Symp Proc"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2435","DOI":"10.1017\/S0033291719002678","volume":"50","author":"Wootton","year":"2020","journal-title":"Psychol Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s10654-015-0011-z","volume":"30","author":"Burgess","year":"2015","journal-title":"Eur J Epidemiol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1093\/ije\/dyx028","volume":"45","author":"Hartwig","year":"2016","journal-title":"Int J Epidemiol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"k601","DOI":"10.1136\/bmj.k601","volume":"362","author":"Davies","year":"2018","journal-title":"BMJ"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.ajhg.2016.11.007","volume":"100","author":"Ahola-Olli","year":"2017","journal-title":"Am J Hum Genet"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/gepi.21965","volume":"40","author":"Bowden","year":"2016","journal-title":"Genet Epidemiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"808832","DOI":"10.3389\/fimmu.2022.808832","volume":"13","author":"Yin","year":"2022","journal-title":"Front Immunol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s40519-023-01538-3","volume":"28","author":"Yuan","year":"2023","journal-title":"Eat Weight Disord"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s10654-017-0255-x","volume":"32","author":"Burgess","year":"2017","journal-title":"Eur J Epidemiol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1038\/s41588-018-0164-2","volume":"50","author":"Verbanck","year":"2018","journal-title":"Nat Genet"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"j5375","DOI":"10.1136\/bmj.j5375","volume":"359","author":"Larsson","year":"2017","journal-title":"BMJ"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1038\/s41588-018-0099-7","volume":"50","author":"Verbanck","year":"2018","journal-title":"Nat Genet"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1734","DOI":"10.1093\/ije\/dyx034","volume":"46","author":"Yavorska","year":"2017","journal-title":"Int J Epidemiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"e34408","DOI":"10.7554\/eLife.34408","volume":"7","author":"Hemani","year":"2018","journal-title":"Elife"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s40257-015-0156-2","volume":"16","author":"Gold","year":"2015","journal-title":"Am J Clin Dermatol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1001\/jamadermatol.2015.2230","volume":"151","author":"Aldrich","year":"2015","journal-title":"JAMA Dermatol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1038\/jidsymp.2011.7","volume":"15","author":"Steinhoff","year":"2011","journal-title":"J Investig Dermatol Symp Proc"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"138","DOI":"10.3390\/biomedicines3010138","volume":"3","author":"H\u00fcbel","year":"2015","journal-title":"Biomedicines"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"8140","DOI":"10.1016\/S0021-9258(18)53072-6","volume":"268","author":"Tamura","year":"1993","journal-title":"J Biol Chem"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"4152","DOI":"10.1016\/S0021-9258(17)41756-X","volume":"269","author":"Liu","year":"1994","journal-title":"J Biol Chem"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/0014-5793(92)80220-b","volume":"301","author":"Gohda","year":"1992","journal-title":"FEBS Lett"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1182\/blood.V82.1.53.bloodjournal82153","volume":"82","author":"Inaba","year":"1993","journal-title":"Blood"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"3964","DOI":"10.1182\/blood.V95.12.3964.012k20_3964_3969","volume":"95","author":"Beilmann","year":"2000","journal-title":"Blood"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1007\/s00011-020-01394-2","volume":"69","author":"Ribatti","year":"2020","journal-title":"Inflamm Res"},{"key":"ref34","first-page":"961","volume":"139","author":"Adamis","year":"1991","journal-title":"Am J Pathol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00441-016-2429-3","volume":"366","author":"Khodadi","year":"2016","journal-title":"Cell Tissue Res"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1111\/all.13301","volume":"73","author":"Babina","year":"2018","journal-title":"Allergy"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1038\/jid.2015.53","volume":"135","author":"Chang","year":"2015","journal-title":"J Investig Dermatol"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"469402","DOI":"10.1155\/2015\/469402","volume":"2015","author":"Karpouzis","year":"2015","journal-title":"Int Sch Res Notices"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.imlet.2019.11.007","volume":"217","author":"Mousavi","year":"2020","journal-title":"Immunol Lett"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s40662-017-0082-x","volume":"4","author":"Hou","year":"2017","journal-title":"Eye Vis"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"107558","DOI":"10.1016\/j.intimp.2021.107558","volume":"95","author":"Deng","year":"2021","journal-title":"Int Immunopharmacol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"27976","DOI":"10.1074\/jbc.M702654200","volume":"282","author":"Jin","year":"2007","journal-title":"J Biol Chem"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1016\/j.biocel.2003.10.019","volume":"36","author":"Maurer","year":"2004","journal-title":"Int J Biochem Cell Biol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2084","DOI":"10.4049\/jimmunol.173.3.2084","volume":"173","author":"Okamatsu","year":"2004","journal-title":"J Immunol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1111\/1751-2980.12232","volume":"16","author":"Li","year":"2015","journal-title":"J Dig Dis"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"3967","DOI":"10.1111\/febs.15236","volume":"287","author":"Sayed","year":"2020","journal-title":"FEBS J"}],"container-title":["Clinical, Cosmetic and Investigational Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/99394","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/99394","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T08:10:13Z","timestamp":1737360613000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/exploring-the-impact-of-systemic-inflammatory-regulators-on-rosacea-ri-peer-reviewed-fulltext-article-CCID"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":46,"URL":"https:\/\/doi.org\/10.2147\/ccid.s495773","relation":{},"ISSN":["1178-7015"],"issn-type":[{"value":"1178-7015","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}