{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:30:40Z","timestamp":1792114240819,"version":"4.4.0"},"reference-count":43,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CEG"],"DOI":"10.2147\/ceg.s532528","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:55:12Z","timestamp":1756464912000},"page":"191-204","source":"Crossref","is-referenced-by-count":1,"title":["Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) rs738409 Variant and Non-Alcoholic Fatty Liver Disease Risk in Vietnamese Working-Age Adults: A Case-Control Study with Metabolic Insights"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5125-1828","authenticated-orcid":true,"given":"Ha","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5524-4626","authenticated-orcid":true,"given":"Duong Hoang Huy","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3641-2821","authenticated-orcid":true,"given":"Thinh","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8629-4593","authenticated-orcid":true,"given":"Hung","family":"Cao Dinh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0635-7979","authenticated-orcid":true,"given":"Tuan","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/liv.14362","volume":"40","author":"Negro","year":"2020","journal-title":"Liver International"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"17","DOI":"10.7570\/jomes22021","volume":"31","author":"Huh","year":"2022","journal-title":"Journal of Obesity & Metabolic Syndrome"},{"key":"ref3","first-page":"22275764","author":"Niriella","year":"2022","journal-title":"medRxiv"},{"key":"ref4","unstructured":"OFFICE NS. Available from: https:\/\/www.nso.gov.vn\/en\/homepage\/. Accessed August 19, 2025."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1509232","DOI":"10.3389\/fnut.2025.1509232","volume":"12","author":"Wang","year":"2025","journal-title":"Frontiers in Nutrition"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1852","DOI":"10.1186\/s12889-024-19047-y","volume":"24","author":"J-j","year":"2024","journal-title":"BMC Public Health"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.numecd.2023.10.002","volume":"34","author":"Ho","year":"2024","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1001\/jama.2023.17935","volume":"330","author":"Leung","year":"2023","journal-title":"JAMA"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/hep.29367","volume":"67","author":"Chalasani","year":"2018","journal-title":"Hepatology"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"841","DOI":"10.3350\/cmh.2022.0239","volume":"28","author":"Le","year":"2022","journal-title":"Clin Mol Hepatol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1097\/HEP.0000000000000004","volume":"77","author":"Younossi","year":"2023","journal-title":"Hepatology"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1007\/s12072-024-10702-5","volume":"18","author":"Zhang","year":"2024","journal-title":"Hepatol Int"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"S32","DOI":"10.3350\/cmh.2024.0431","volume":"31","author":"Younossi","year":"2025","journal-title":"Clin Mol Hepatol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1159\/000514953","volume":"39","author":"Park","year":"2021","journal-title":"Digest Dis"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"486","DOI":"10.18203\/2394-6040.ijcmph20223578","volume":"10","author":"Alharbi","year":"2023","journal-title":"International Journal of Community Medicine and Public Health"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"235","DOI":"10.3350\/cmh.2023.0485","volume":"30","author":"MH","year":"2024","journal-title":"Clinical and Molecular Hepatology"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"102003","DOI":"10.1016\/j.clinre.2022.102003","volume":"46","author":"Sharma","year":"2022","journal-title":"Clinics and Research in Hepatology and Gastroenterology"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e14324","DOI":"10.1097\/MD.0000000000014324","volume":"98","author":"Dai","year":"2019","journal-title":"Medicine"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1002\/cld.948","volume":"16","author":"Samji","year":"2020","journal-title":"Clinical Liver Disease"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"304","DOI":"10.3389\/fmed.2019.00304","volume":"6","author":"Dong","year":"2019","journal-title":"Frontiers in medicine"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"112","DOI":"10.7326\/0003-4819-132-2-200001180-00004","volume":"132","author":"Bellentani","year":"2000","journal-title":"Annals of Internal medicine"},{"key":"ref22","volume-title":"Statistical Methods for Rates and Proportions","year":"2013"},{"key":"ref23","author":"Tan","year":"2004","journal-title":"The Lancet"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1242\/dmm.001180","volume":"2","author":"Huang","year":"2009","journal-title":"Dis Models Mech"},{"key":"ref25","volume":"536","author":"V\u00e2n","year":"2024","journal-title":"T\u1ea1p ch\u00ed Y h\u1ecdc Vi\u1ec7t Nam"},{"key":"ref26","volume":"6","author":"Kim","year":"2020","journal-title":"Hepatoma Res"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1016\/j.jhep.2020.02.020","volume":"72","author":"Tr\u00e9po","year":"2020","journal-title":"Journal of Hepatology"},{"key":"ref28","first-page":"1388","volume":"64","author":"Marchesini","year":"2016","journal-title":"Journal of Hepatology"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/j.eprac.2022.03.010","volume":"28","author":"Cusi","year":"2022","journal-title":"Endocrine Practice"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1097\/HEP.0000000000000323","volume":"77","author":"Rinella","year":"2023","journal-title":"Hepatology"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1016\/j.jhep.2012.07.030","volume":"57","author":"Pirazzi","year":"2012","journal-title":"Journal of Hepatology"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1194\/jlr.M046607","volume":"55","author":"Ruhanen","year":"2014","journal-title":"Journal of Lipid Research"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12944-018-0848-8","volume":"17","author":"Wang","year":"2018","journal-title":"Lipids in Health and Disease"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"101728","DOI":"10.1016\/j.molmet.2023.101728","volume":"73","author":"Mocciaro","year":"2023","journal-title":"Molecular Metabolism"},{"key":"ref35","unstructured":"SNP.rs738409. Available from: https:\/\/www.ncbi.nlm.nih.gov\/snp\/rs738409. Accessed April 4, 2025."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2350-11-172","volume":"11","author":"Hotta","year":"2010","journal-title":"BMC Medical Genetics"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2350-13-1","volume":"13","author":"Li","year":"2012","journal-title":"BMC Medical Genetics"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1007\/s00439-012-1141-y","volume":"131","author":"Zain","year":"2012","journal-title":"Human Genetics"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"3150","DOI":"10.1002\/sim.2250","volume":"25","author":"Zheng","year":"2006","journal-title":"Statistics in Medicine"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.17762\/jaz.v44iS-1.1248","volume":"44","author":"Rachana Raveendran","year":"2023","journal-title":"J Adv Zool"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"bvaf110","DOI":"10.1210\/jendso\/bvaf110","volume":"9","author":"Bril","year":"2025","journal-title":"J Endocr Soc"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1999","DOI":"10.1016\/j.cgh.2024.03.006","volume":"22","author":"Younossi","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"439","DOI":"10.14218\/JCTH.2021.00286","volume":"10","author":"Li","year":"2021","journal-title":"Journal of Clinical and Translational Hepatology"}],"container-title":["Clinical and Experimental Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/106339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/106339","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:55:14Z","timestamp":1756464914000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/patatin-like-phospholipase-domain-containing-protein-3-pnpla3-rs738409-peer-reviewed-fulltext-article-CEG"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":43,"URL":"https:\/\/doi.org\/10.2147\/ceg.s532528","relation":{},"ISSN":["1178-7023"],"issn-type":[{"value":"1178-7023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8]]}}}