{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T20:33:30Z","timestamp":1787690010101,"version":"build-2784847793"},"reference-count":96,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Interventions in Aging"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.2147\/ciia.2007.2.1.55","type":"journal-article","created":{"date-parts":[[2007,5,25]],"date-time":"2007-05-25T10:57:14Z","timestamp":1180090634000},"page":"55-64","source":"Crossref","is-referenced-by-count":41,"title":["The differential effects of bisphosphonates, SERMS (selective estrogen receptor modulators), and parathyroid hormone on bone remodeling in osteoporosis"],"prefix":"10.2147","volume":"2","author":[{"given":"Silvia","family":"Migliaccio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Brama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Spera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","reference":[{"key":"p_1_449","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/oxfordjournals.bmb.a072550","volume":"48","author":"Barrett-Connor E.","year":"1992","journal-title":"Br Med Bull"},{"key":"p_2_450","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.7.847"},{"key":"p_3_451","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.4.517"},{"key":"p_4_452","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(01)00412-4"},{"key":"p_5_453","doi-asserted-by":"publisher","DOI":"10.1007\/s001980170020"},{"key":"p_6_454","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)07088-2"},{"key":"p_7_455","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031975"},{"key":"p_8_456","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1007\/s00198-002-1347-2","volume":"3","author":"Boivin G","year":"2003","journal-title":"Osteoporos Int"},{"key":"p_9_457","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/jbmr.5650100207","volume":"10","author":"Boyce RW","year":"1995","journal-title":"J Bone Miner Res"},{"key":"p_10_458","doi-asserted-by":"publisher","DOI":"10.1007\/BF01771666"},{"key":"p_11_459","doi-asserted-by":"publisher","DOI":"10.1038\/39645"},{"key":"p_12_460","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.145.3.527"},{"key":"p_13_461","doi-asserted-by":"publisher","DOI":"10.1001\/jama.276.17.1404"},{"key":"p_14_462","first-page":"124","volume":"65","author":"Cauley JA","year":"2001","journal-title":"Breast Cancer Rest Treatment"},{"key":"p_15_463","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1533207100"},{"key":"p_16_464","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.040325"},{"key":"p_17_465","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(00)00490-3"},{"key":"p_18_466","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199506153322401"},{"key":"p_19_467","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/oxfordjournals.bmb.a072549","volume":"48","author":"Compston JE.","year":"1992","journal-title":"Br Med Bull"},{"key":"p_20_468","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.5.925"},{"key":"p_21_469","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s11914-004-0008-0","volume":"2","author":"Cosman F","year":"2004","journal-title":"Curr Osteoporos Rep"},{"key":"p_22_470","doi-asserted-by":"publisher","DOI":"10.1210\/er.2001-2002"},{"key":"p_23_471","first-page":"2189","volume":"281","author":"Cummings SR","year":"1999","journal-title":"Multiple Outcomes of Raloxifene Evaluation. JAMA"},{"key":"p_24_472","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/90.19.1461"},{"key":"p_25_473","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712043372301"},{"key":"p_26_474","doi-asserted-by":"publisher","DOI":"10.1210\/jc.87.8.3609"},{"key":"p_27_475","first-page":"S42","volume":"3","author":"Del Puente A","year":"2004","journal-title":"Aging Clin Exp Res"},{"key":"p_28_476","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2001.16.10.1846"},{"key":"p_29_477","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(02)00145-7"},{"key":"p_30_478","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-002-2104-4"},{"key":"p_31_479","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.7.637"},{"key":"p_32_480","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.040117"},{"key":"p_33_481","doi-asserted-by":"publisher","DOI":"10.1126\/science.3283939"},{"key":"p_34_482","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/90.18.1371"},{"key":"p_35_483","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2003.01174.x"},{"key":"p_36_484","first-page":"S37","volume":"3","author":"Gandolini G","year":"2004","journal-title":"Aging Clin Exp Res"},{"key":"p_37_485","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0795"},{"key":"p_38_486","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-857X(05)70197-6"},{"key":"p_39_487","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.14.1344"},{"key":"p_40_488","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-003-0042-4"},{"key":"p_41_489","doi-asserted-by":"publisher","DOI":"10.1210\/er.2004-0006"},{"key":"p_42_490","first-page":"268","volume":"4","author":"Hofbauer LC","year":"2004","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"p_43_491","doi-asserted-by":"publisher","DOI":"10.1038\/nm1096-1132"},{"key":"p_44_492","unstructured":"Jensen EV. 1991. Overview of the nuclear receptor family. In: Parker MG, (ed). Nuclear hormone receptors: molecular mechanisms, cellular functions, clinical abnormalities. London: Acad Pr, pp 1-13."},{"key":"p_45_493","doi-asserted-by":"publisher","DOI":"10.1126\/science.1621100"},{"key":"p_46_494","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/978-3-642-75515-6_3","volume":"83","author":"Juppner H","year":"1991","journal-title":"Curr Top Pathol"},{"key":"p_47_495","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.11.1215"},{"key":"p_48_496","doi-asserted-by":"publisher","DOI":"10.1016\/0169-6009(91)90021-Q"},{"key":"p_49_497","first-page":"531","volume":"8","author":"Kauffman RF","year":"1995","journal-title":"Drug News Perspect"},{"key":"p_50_498","doi-asserted-by":"publisher","DOI":"10.1210\/en.136.6.2435"},{"key":"p_51_499","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2000.15.4.721"},{"key":"p_52_500","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-128X(99)00014-8"},{"key":"p_53_501","first-page":"612","volume":"36","author":"Liberman UA","year":"1995","journal-title":"N Engl J Med"},{"key":"p_54_502","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)92217-0"},{"key":"p_55_503","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.3.320"},{"key":"p_56_504","doi-asserted-by":"publisher","DOI":"10.1210\/en.2002-221061"},{"key":"p_57_505","doi-asserted-by":"publisher","DOI":"10.1210\/er.21.2.115"},{"key":"p_58_506","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200102013440503"},{"key":"p_59_507","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.0301202"},{"key":"p_60_508","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)02221-4"},{"key":"p_61_509","first-page":"S20","volume":"3","author":"Migliaccio S","year":"2004","journal-title":"Aging Clin Exp Res"},{"key":"p_62_510","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200105103441904"},{"key":"p_63_511","doi-asserted-by":"crossref","unstructured":"Nickelsen T, Lifkin EG, Riggs BL, etal 1999. Raloxifene hydrochloride, a selective estrogen receptor modulator: safety assessment of effects on cognitive function and mood in postmenopausal women. Psychon euroendocrinology, 24:115-28.","DOI":"10.1016\/S0306-4530(98)00041-9"},{"key":"p_64_512","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.6.785"},{"key":"p_65_513","unstructured":"Nilsson S, Gustafsson JA. 2002. Structure and function of the estrogen receptor. In: Manni A, Verderame MF (eds). Contemporary endocrinology: Selective estrogen receptor modulators: Research and clinical applications. Totowa, NJ, Humana Pr. pp 3-18."},{"key":"p_66_514","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.12.5134"},{"key":"p_67_515","doi-asserted-by":"publisher","DOI":"10.1007\/PL00004171"},{"key":"p_68_516","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1200\/JCO.1996.14.1.78","volume":"14","author":"Powles TJ","year":"1996","journal-title":"J Clin Oncol"},{"key":"p_69_517","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000422331","volume":"72","author":"Raisz LG.","year":"1993","journal-title":"World Rev Nutr Diet"},{"key":"p_70_518","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010074422268"},{"key":"p_71_519","doi-asserted-by":"publisher","DOI":"10.1016\/S1049-3867(05)80275-0"},{"key":"p_72_520","doi-asserted-by":"publisher","DOI":"10.1007\/s001980050010"},{"key":"p_73_521","doi-asserted-by":"publisher","DOI":"10.2174\/138161205774580750"},{"key":"p_74_522","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-002-1312-0"},{"key":"p_75_523","first-page":"711","volume":"4","author":"Reszka AA","year":"2004","journal-title":"Mini Rev Med Chem"},{"key":"p_76_524","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra022219"},{"key":"p_77_525","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(01)00485-9"},{"key":"p_78_526","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.3.321"},{"key":"p_79_527","doi-asserted-by":"publisher","DOI":"10.1185\/030079903125003125"},{"key":"p_80_528","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(98)00049-8"},{"key":"p_81_529","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1096\/fasebj.10.8.8666168","volume":"10","author":"Sato M","year":"1996","journal-title":"FASEB J"},{"key":"p_82_530","first-page":"1","volume":"12","author":"Schnitzer T","year":"2000","journal-title":"Aging (Milano)"},{"key":"p_83_531","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-003-1465-5"},{"key":"p_84_532","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-003-1465-5"},{"key":"p_85_533","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1210\/endo-16-5-547","volume":"16","author":"Selye H.","year":"1932","journal-title":"Endocrinology"},{"key":"p_86_534","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jbmr.5650111202","volume":"11","author":"Short LL","year":"1996","journal-title":"J Bone Miner Res"},{"key":"p_87_535","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(02)00946-8"},{"key":"p_88_536","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(01)00685-8"},{"key":"p_89_537","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1995.0019"},{"key":"p_90_538","doi-asserted-by":"publisher","DOI":"10.1210\/en.140.7.3363"},{"key":"p_91_539","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1999.14.6.923"},{"key":"p_92_540","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.18.1445"},{"key":"p_93_541","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.3.321"},{"key":"p_94_542","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104193441604"},{"key":"p_95_543","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5279.1222"},{"key":"p_96_544","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.7.3597"}],"container-title":["Clinical Interventions in Aging"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,4,28]],"date-time":"2019-04-28T09:56:14Z","timestamp":1556445374000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.atypon-link.com\/DMP\/doi\/abs\/10.2147\/ciia.2007.2.1.55"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":96,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.2147\/ciia.2007.2.1.55"],"URL":"https:\/\/doi.org\/10.2147\/ciia.2007.2.1.55","relation":{},"ISSN":["1176-9092"],"issn-type":[{"value":"1176-9092","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}