{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:37:38Z","timestamp":1776400658868,"version":"3.51.2"},"reference-count":37,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CMAR"],"DOI":"10.2147\/cmar.s545808","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T06:35:10Z","timestamp":1766385310000},"page":"3227-3240","source":"Crossref","is-referenced-by-count":1,"title":["ALPP Induces Epithelial-Mesenchymal Transition by Activating the Wnt\/\u03b2-Catenin Signaling Pathway in Colorectal Cancer Cells"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Bo","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1502-6273","authenticated-orcid":true,"given":"Baokun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2287-7797","authenticated-orcid":true,"given":"Xuhua","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingming","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"233","DOI":"10.3322\/caac.21772","volume":"73","author":"Siegel","year":"2023","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1002\/jso.27320","volume":"127","author":"Kim","year":"2023","journal-title":"J Surg Oncol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1111\/1751-2980.13130","volume":"23","author":"Deng","year":"2022","journal-title":"J Dig Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1136\/gutjnl-2022-327736","volume":"72","author":"Morgan","year":"2023","journal-title":"Gut"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1081585","DOI":"10.3389\/fendo.2022.1081585","volume":"13","author":"Zhao","year":"2022","journal-title":"Front Endocrinol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1200\/jco.22.01690","volume":"41","author":"Morris","year":"2023","journal-title":"J Clin Oncol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"zcad021","DOI":"10.1093\/narcan\/zcad021","volume":"5","author":"Zhao","year":"2023","journal-title":"NAR Cancer"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.3390\/biom12121723","volume":"12","author":"Tan","year":"2022","journal-title":"Biomolecules"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/s41419-022-05547-5","volume":"14","author":"Chi","year":"2023","journal-title":"Cell Death Dis"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"880","DOI":"10.2174\/1568026623666230303101810","volume":"23","author":"Zhang","year":"2023","journal-title":"Curr Top Med Chem"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"3580","DOI":"10.3390\/cells11223580","volume":"11","author":"Wang","year":"2022","journal-title":"Cells"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1038\/s41419-022-05200-1","volume":"13","author":"Yao","year":"2022","journal-title":"Cell Death Dis"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"823","DOI":"10.3389\/fonc.2020.00823","volume":"10","author":"Wang","year":"2020","journal-title":"Front Oncol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1039\/d3md00565h","volume":"15","author":"Tyagi","year":"2024","journal-title":"RSC Med Chem"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"6315","DOI":"10.3390\/ijms24076315","volume":"24","author":"Abreu","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1021\/acs.nanolett.0c04435","volume":"21","author":"Li","year":"2021","journal-title":"Nano Lett"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.humpath.2018.11.019","volume":"86","author":"Liu","year":"2019","journal-title":"Hum Pathol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"15799","DOI":"10.1021\/acs.jmedchem.1c01103","volume":"64","author":"Bassi","year":"2021","journal-title":"J Med Chem"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1002\/cjp2.237","volume":"7","author":"Reiswich","year":"2021","journal-title":"J Pathol Clin Res"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.canlet.2021.11.003","volume":"526","author":"Sun","year":"2022","journal-title":"Cancer Lett"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.2741\/4877","volume":"25","author":"Li","year":"2020","journal-title":"Front Biosci"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1186\/s12967-024-05391-5","volume":"22","author":"Huang","year":"2024","journal-title":"J Transl Med"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"690298","DOI":"10.3389\/fonc.2021.690298","volume":"11","author":"Zhao","year":"2021","journal-title":"Front Oncol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"5599","DOI":"10.2147\/cmar.S318704","volume":"13","author":"Fang","year":"2021","journal-title":"Cancer Manag Res"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"2607","DOI":"10.3390\/cells10102607","volume":"10","author":"Zucha","year":"2021","journal-title":"Cells"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.annonc.2022.10.003","volume":"34","author":"Cervantes","year":"2023","journal-title":"Ann Oncol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1186\/s12943-022-01616-7","volume":"21","author":"Zhao","year":"2022","journal-title":"Mol Cancer"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"110909","DOI":"10.1016\/j.biopha.2020.110909","volume":"133","author":"Babaei","year":"2021","journal-title":"Biomed Pharmacother"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"166431","DOI":"10.1016\/j.bbadis.2022.166431","volume":"1868","author":"Gundamaraju","year":"2022","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.tcb.2018.12.001","volume":"29","author":"Pastushenko","year":"2019","journal-title":"Trends Cell Biol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"101276","DOI":"10.1016\/j.drup.2025.101276","volume":"83","author":"Jiang","year":"2025","journal-title":"Drug Resist Updat"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"6764","DOI":"10.3748\/wjg.v22.i30.6764","volume":"22","author":"Gurzu","year":"2016","journal-title":"World J Gastroenterol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1038\/nature16064","volume":"527","author":"Zheng","year":"2015","journal-title":"Nature"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.biochi.2018.11.003","volume":"157","author":"Aghabozorgi","year":"2019","journal-title":"Biochimie"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1186\/s13046-019-1330-9","volume":"38","author":"Li","year":"2019","journal-title":"J Exp Clin Cancer Res"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.canlet.2021.10.034","volume":"525","author":"Zhou","year":"2022","journal-title":"Cancer Lett"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"e108647","DOI":"10.15252\/embj.2021108647","volume":"40","author":"Brabletz","year":"2021","journal-title":"EMBO J"}],"container-title":["Cancer Management and Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/110209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/110209","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T06:35:11Z","timestamp":1766385311000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/alpp-induces-epithelial-mesenchymal-transition-by-activating-the-wnt-c-peer-reviewed-fulltext-article-CMAR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":37,"URL":"https:\/\/doi.org\/10.2147\/cmar.s545808","relation":{},"ISSN":["1179-1322"],"issn-type":[{"value":"1179-1322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]}}}