{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T07:57:14Z","timestamp":1785830234501,"version":"3.56.0"},"reference-count":129,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["COPD"],"DOI":"10.2147\/copd.s240033","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T20:26:45Z","timestamp":1591216005000},"page":"1269-1285","source":"Crossref","is-referenced-by-count":18,"title":["<p>Day and Night Control of COPD and Role of Pharmacotherapy: A Review<\/p>"],"prefix":"10.2147","volume":"Volume 15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7013-4280","authenticated-orcid":true,"given":"Alberto","family":"Braghiroli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2460-4709","authenticated-orcid":true,"given":"Fulvio","family":"Braido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8029-2159","authenticated-orcid":true,"given":"Alessio","family":"Piraino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7801-5040","authenticated-orcid":true,"given":"Paola","family":"Rogliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierachille","family":"Santus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6400-6573","authenticated-orcid":true,"given":"Nicola","family":"Scichilone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1016\/S0140-6736(12)61728-0","volume":"380","author":"Lozano","year":"2012","journal-title":"Lancet"},{"key":"ref2","unstructured":"Available from: https:\/\/goldcopd.org\/wp-content\/uploads\/2019\/11\/GOLD-2020-REPORT-ver1.0wms.pdf. Accessed May 5, 2020."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"697","DOI":"10.2147\/COPD.S32675","volume":"7","author":"Jones","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1185\/03007990903103006","volume":"25","author":"Partridge","year":"2009","journal-title":"Curr Med Res Opin"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1159\/000368365","volume":"89","author":"Braido","year":"2015","journal-title":"Respiration"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1183\/09059180.00004311","volume":"20","author":"Agusti","year":"2011","journal-title":"Eur Respir Rev"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"16040","DOI":"10.1038\/npjpcrm.2016.40","volume":"21","author":"Tsiligianni","year":"2016","journal-title":"NPJ Prim Care Respir Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1080\/15412555.2017.1338681","volume":"14","author":"Kr\u00f6nig","year":"2017","journal-title":"COPD"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1055\/s-0034-1365156","volume":"68","author":"Koehler","year":"2014","journal-title":"Pneumologie"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.2147\/COPD.S154539","volume":"13","author":"Fischer","year":"2018","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1111\/crj.12738","volume":"12","author":"Akinci","year":"2018","journal-title":"Clin Respir J"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.rmed.2005.04.029","volume":"100","author":"Lindberg","year":"2006","journal-title":"Respir Med"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1164\/ajrccm.155.1.9001298","volume":"155","author":"O\u2019Donnell","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1183\/09031936.00051110","volume":"37","author":"Kessler","year":"2011","journal-title":"Eur Respir J"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1080\/15412550802237531","volume":"5","author":"Decramer","year":"2008","journal-title":"COPD"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"3043","DOI":"10.2147\/COPD.S122433","volume":"11","author":"Contoli","year":"2016","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1183\/16000617.0054-2016","volume":"25","author":"O\u2019Donnell","year":"2016","journal-title":"Eur Respir Rev"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1378\/chest.09-1847","volume":"137","author":"Hannink","year":"2010","journal-title":"Chest"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1186\/s12890-018-0723-4","volume":"18","author":"Katz","year":"2018","journal-title":"BMC Pulm Med"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1152\/japplphysiol.00791.2016","volume":"124","author":"Kang","year":"2018","journal-title":"J Appl Physiol (1985)"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.resp.2016.09.006","volume":"234","author":"Pecchiari","year":"2016","journal-title":"Respir Physiol Neurobiol"},{"key":"ref22","first-page":"1266","volume":"2017","author":"Pecchiari","year":"1985","journal-title":"J Appl Physiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.phrs.2018.05.010","volume":"133","author":"Santus","year":"2018","journal-title":"Pharmacol Res"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1164\/rccm.201512-2340ED","volume":"193","author":"Watz","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/j.jacc.2011.11.040","volume":"59","author":"Ather","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.2147\/COPD.S91684","volume":"10","author":"Santus","year":"2015","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1164\/rccm.201508-1647OC","volume":"193","author":"Stone","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/S2213-2600(18)30054-7","volume":"6","author":"Hohlfeld","year":"2018","journal-title":"Lancet Respir Med"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1080\/15412555.2019.1659760","volume":"16","author":"Radovanovic","year":"2019","journal-title":"COPD"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1152\/jappl.1981.51.3.557","volume":"51","author":"Tabachnik","year":"1981","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"363","DOI":"10.2147\/copd.2006.1.4.363","volume":"1","author":"Marrone","year":"2006","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1183\/09031936.03.00066802","volume":"21","author":"O\u2019Donoghue","year":"2003","journal-title":"Eur Respir J"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1136\/thx.41.9.676","volume":"41","author":"Catterall","year":"1986","journal-title":"Thorax"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1111\/j.1365-2125.1989.tb03540.x","volume":"28","author":"Morrison","year":"1989","journal-title":"Br J Clin Pharmacol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1136\/thoraxjnl-2013-203482","volume":"69","author":"Durrington","year":"2014","journal-title":"Thorax"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"S188","DOI":"10.1164\/ajrccm.157.5.rsaa-4","volume":"157","author":"Martin","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1183\/09031936.00200212","volume":"42","author":"Bateman","year":"2013","journal-title":"Eur Respir J"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/j.1475-097X.2011.01046.x","volume":"32","author":"Lee","year":"2012","journal-title":"Clin Physiol Funct Imaging"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s40261-015-0322-6","volume":"35","author":"Iqbal","year":"2015","journal-title":"Clin Drug Investig"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.rmed.2007.12.014","volume":"102","author":"van den Bemt","year":"2008","journal-title":"Respir Med"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1136\/thoraxjnl-2014-205507","volume":"69","author":"Agusti","year":"2014","journal-title":"Thorax"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1183\/09031936.00123709","volume":"36","author":"Partridge","year":"2010","journal-title":"Eur Respir J"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1183\/09031936.00102509","volume":"34","author":"Jones","year":"2009","journal-title":"Eur Respir J"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s12931-016-0372-1","volume":"17","author":"Jones","year":"2016","journal-title":"Respir Res"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s12931-014-0124-z","volume":"15","author":"Leidy","year":"2014","journal-title":"Respir Res"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"3719","DOI":"10.2147\/COPD.S178149","volume":"13","author":"Soler-Catalu\u00f1a","year":"2018","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ejim.2016.05.030","volume":"34","author":"Braido","year":"2016","journal-title":"Eur J Intern Med"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s00408-009-9147-5","volume":"187","author":"Nunes","year":"2009","journal-title":"Lung"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.sleep.2011.12.007","volume":"13","author":"Omachi","year":"2012","journal-title":"Sleep Med"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1183\/09031936.00196713","volume":"43","author":"Lange","year":"2014","journal-title":"Eur Respir J"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"441","DOI":"10.3109\/15412550903433000","volume":"6","author":"Kwon","year":"2009","journal-title":"COPD"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1080\/15412555.2018.1504015","volume":"15","author":"Basile","year":"2018","journal-title":"COPD"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1186\/1477-7525-7-98","volume":"7","author":"Pokrzywinski","year":"2009","journal-title":"Health Qual Life Outcomes"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1056\/NEJMoa063070","volume":"356","author":"Calverley","year":"2007","journal-title":"N Engl J Med"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ejim.2017.05.021","volume":"43","author":"Canonica","year":"2017","journal-title":"Eur J Intern Med"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1093\/sleep\/26.3.318","volume":"26","author":"Bellia","year":"2003","journal-title":"Sleep"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1124\/pr.111.004580","volume":"64","author":"Cazzola","year":"2012","journal-title":"Pharmacol Rev"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1186\/1465-9921-11-149","volume":"11","author":"Tashkin","year":"2010","journal-title":"Respir Res"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.ejphar.2015.05.020","volume":"761","author":"Calzetta","year":"2015","journal-title":"Eur J Pharmacol"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"175","DOI":"10.3109\/15412555.2014.922172","volume":"12","author":"Cazzola","year":"2015","journal-title":"COPD"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1159\/000452479","volume":"93","author":"Crisafulli","year":"2017","journal-title":"Respiration"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1038\/bjp.2008.185","volume":"154","author":"Wessler","year":"2008","journal-title":"Br J Pharmacol"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1016\/j.bbadis.2012.03.002","volume":"1822","author":"Profita","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/s12931-016-0386-8","volume":"17","author":"Cazzola","year":"2016","journal-title":"Respir Res"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/S0140-6736(94)90127-9","volume":"343","author":"Sullivan","year":"1994","journal-title":"Lancet"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1006\/pulp.1994.1001","volume":"7","author":"Nicholson","year":"1994","journal-title":"Pulm Pharmacol"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"8921","DOI":"10.1073\/pnas.132556899","volume":"99","author":"Ito","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1136\/thorax.55.10.837","volume":"55","author":"Lim","year":"2000","journal-title":"Thorax"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"2754","DOI":"10.1183\/09031936.97.10122754","volume":"10","author":"Ukena","year":"1997","journal-title":"Eur Respir J"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1124\/jpet.112.198481","volume":"344","author":"Slack","year":"2013","journal-title":"J Pharmacol Exp Ther"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.ejphar.2017.07.026","volume":"812","author":"Calzetta","year":"2017","journal-title":"Eur J Pharmacol"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.pupt.2018.01.003","volume":"49","author":"Naline","year":"2018","journal-title":"Pulm Pharmacol Ther"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/S2213-2600(15)00106-X","volume":"3","author":"Pascoe","year":"2015","journal-title":"Lancet Respir Med"},{"key":"ref74","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1016\/S0140-6736(18)30206-X","volume":"391","author":"Papi","year":"2018","journal-title":"Lancet"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1056\/NEJMoa1713901","volume":"378","author":"Lipson","year":"2018","journal-title":"N Engl J Med"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1056\/NEJMoa1407154","volume":"371","author":"Magnussen","year":"2014","journal-title":"N Engl J Med"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.pupt.2017.06.002","volume":"45","author":"Calzetta","year":"2017","journal-title":"Pulm Pharmacol Ther"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.1056\/NEJMe1409219","volume":"371","author":"Reilly","year":"2014","journal-title":"N Engl J Med"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1164\/rccm.201803-0405OC","volume":"198","author":"Chapman","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"ref80","first-page":"CD006829","volume":"9","author":"Nannini","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"ref81","first-page":"CD006826","volume":"8","author":"Nannini","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"ref82","first-page":"CD003794","volume":"11","author":"Nannini","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/s00408-014-9611-8","volume":"192","author":"Manoharan","year":"2014","journal-title":"Lung"},{"key":"ref84","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01230-2018","volume":"52","author":"Vestbo","year":"2018","journal-title":"Eur Respir J"},{"key":"ref85","doi-asserted-by":"publisher","first-page":"531","DOI":"10.2147\/COPD.S196383","volume":"28","author":"Singh","year":"2019","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref86","doi-asserted-by":"publisher","first-page":"587","DOI":"10.2147\/COPD.S32765","volume":"7","author":"Jen","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref87","doi-asserted-by":"crossref","first-page":"e63430","DOI":"10.1371\/journal.pone.0063430","volume":"8","author":"Kunz","year":"2013","journal-title":"PLoS One"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"95","DOI":"10.2147\/COPD.S27480","volume":"7","author":"Tantucci","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref89","volume":"53","author":"Singh","year":"2019","journal-title":"Eur Respir J"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/S2213-2600(18)30327-8","volume":"6","author":"Ferguson","year":"2018","journal-title":"Lancet Respir Med"},{"key":"ref91","doi-asserted-by":"publisher","first-page":"1801586","DOI":"10.1183\/13993003.01586-2018","volume":"52","author":"Cazzola","year":"2018","journal-title":"Eur Respir J"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1345\/aph.1L546","volume":"43","author":"Kelly","year":"2009","journal-title":"Ann Pharmacother"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1186\/1465-9921-12-132","volume":"12","author":"Woodcock","year":"2011","journal-title":"Respir Res"},{"key":"ref94","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/1465-9921-12-160","volume":"12","author":"Woodcock","year":"2011","journal-title":"Respir Res"},{"key":"ref95","unstructured":"Global Initiative for Asthma; 2019. Available from: https:\/\/ginasthma.org\/. Accessed May 5, 2020."},{"key":"ref96","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.2147\/COPD.S121723","volume":"12","author":"Beier","year":"2017","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s12931-016-0340-9","volume":"17","author":"Calverley","year":"2016","journal-title":"Respir Res"},{"key":"ref98","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/1471-2466-12-74","volume":"12","author":"Arievich","year":"2012","journal-title":"BMC Pulm Med"},{"key":"ref99","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1136\/thorax.58.10.855","volume":"58","author":"Calverley","year":"2003","journal-title":"Thorax"},{"key":"ref100","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1016\/j.ejim.2012.04.004","volume":"23","author":"Santus","year":"2012","journal-title":"Eur J Intern Med"},{"key":"ref101","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1056\/NEJMra050100","volume":"353","author":"Osterberg","year":"2005","journal-title":"N Engl J Med"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1002\/pds.4059","volume":"25","author":"Belleudi","year":"2016","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"ref103","doi-asserted-by":"publisher","first-page":"3198","DOI":"10.1378\/chest.128.5.3198","volume":"128","author":"George","year":"2005","journal-title":"Chest"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.rmed.2008.11.004","volume":"103","author":"Jung","year":"2009","journal-title":"Respir Med"},{"key":"ref105","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1002\/pds.1321","volume":"16","author":"Krigsman","year":"2007","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.rmed.2017.06.007","volume":"129","author":"Rogliani","year":"2017","journal-title":"Respir Med"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1136\/thx.2007.086041","volume":"63","author":"Bourbeau","year":"2008","journal-title":"Thorax"},{"key":"ref108","doi-asserted-by":"publisher","first-page":"2500","DOI":"10.1111\/ggi.13115","volume":"17","author":"Vetrano","year":"2017","journal-title":"Geriatr Gerontol Int"},{"key":"ref109","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.rmed.2016.11.008","volume":"122","author":"Mueller","year":"2017","journal-title":"Respir Med"},{"key":"ref110","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.rmed.2011.01.005","volume":"105","author":"Melani","year":"2011","journal-title":"Respir Med"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"785","DOI":"10.7326\/0003-4819-157-11-201212040-00538","volume":"157","author":"Viswanathan","year":"2012","journal-title":"Ann Intern Med"},{"key":"ref112","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.pcrj.2005.01.002","volume":"14","author":"Guest","year":"2005","journal-title":"Prim Care Respir J"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2466-10-1","volume":"10","author":"Price","year":"2010","journal-title":"BMC Pulm Med"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"S107","DOI":"10.1016\/j.jaci.2003.09.019","volume":"112","author":"Storms","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"ref115","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1136\/adc.83.4.330","volume":"83","author":"Jonasson","year":"2000","journal-title":"Arch Dis Child"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"289","DOI":"10.2147\/COPD.S96948","volume":"10","author":"Izquierdo","year":"2016","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref117","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/j.rmed.2010.09.006","volume":"105","author":"Toy","year":"2011","journal-title":"Respir Med"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"161","DOI":"10.4104\/pcrj.2013.00017","volume":"22","author":"Price","year":"2013","journal-title":"Prim Care Respir J"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"871","DOI":"10.2147\/COPD.S49621","volume":"9","author":"Smith","year":"2014","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"390","DOI":"10.3109\/15412555.2014.974734","volume":"12","author":"Battaglia","year":"2015","journal-title":"COPD"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"17","DOI":"10.2147\/PPA.S5627","volume":"4","author":"Scichilone","year":"2010","journal-title":"Patient Prefer Adherence"},{"key":"ref122","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.pupt.2015.02.006","volume":"31","author":"Scichilone","year":"2015","journal-title":"Pulm Pharmacol Ther"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1159\/000109374","volume":"75","author":"Wieshammer","year":"2008","journal-title":"Respiration"},{"key":"ref124","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1183\/09031936.02.00218402","volume":"19","author":"Giraud","year":"2002","journal-title":"Eur Respir J"},{"key":"ref125","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1183\/09031936.99.14510349","volume":"14","author":"van der Palen","year":"1999","journal-title":"Eur Respir J"},{"key":"ref126","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1378\/chest.127.1.335","volume":"127","author":"Dolovich","year":"2005","journal-title":"Chest"},{"key":"ref127","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.chest.2016.07.035","volume":"151","author":"Lavorini","year":"2017","journal-title":"Chest"},{"key":"ref128","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S2213-2600(17)30207-2","volume":"5","author":"Han","year":"2017","journal-title":"Lancet Respir Med"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1164\/rccm.200612-1772OC","volume":"176","author":"Hogg","year":"2007","journal-title":"Am J Respir Crit Care Med"}],"container-title":["International Journal of Chronic Obstructive Pulmonary Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=58620","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=58620","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T20:26:53Z","timestamp":1591216013000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/day-and-night-control-of-copd-and-role-of-pharmacotherapy-a-review-peer-reviewed-article-COPD"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":129,"URL":"https:\/\/doi.org\/10.2147\/copd.s240033","relation":{},"ISSN":["1178-2005"],"issn-type":[{"value":"1178-2005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6]]}}}