{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T15:38:25Z","timestamp":1782401905087,"version":"3.54.5"},"reference-count":57,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["COPD"],"DOI":"10.2147\/copd.s365771","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T23:50:07Z","timestamp":1662421807000},"page":"2127-2136","source":"Crossref","is-referenced-by-count":17,"title":["New Perspectives on Chronic Obstructive Pulmonary Disease"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Bartolome R","family":"Celli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Vogelmeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvar","family":"Agusti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1164\/rccm.201204-0596PP","volume":"187","author":"Vestbo","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1056\/NEJMra1900500","volume":"381","author":"Celli","year":"2019","journal-title":"N Engl J Med"},{"key":"ref3","unstructured":"Global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; 2022. Available From: https:\/\/goldcopd.org\/wp-content\/uploads\/2021\/11\/GOLD-REPORT-2022-v1.0-12Nov2021_WMV.pdf. Accessed November 2021."},{"key":"ref4","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1136\/thoraxjnl-2014-205507","volume":"69","author":"Agusti","year":"2014","journal-title":"Thorax"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1136\/bmj.1.6077.1645","volume":"1","author":"Fletcher","year":"1977","journal-title":"Br Med J"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1001\/jama.1994.03520190043033","volume":"272","author":"Anthonisen","year":"1994","journal-title":"JAMA"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/S0140-6736(98)10019-3","volume":"353","author":"Vestbo","year":"1999","journal-title":"Lancet."},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1056\/NEJM199906243402503","volume":"340","author":"Pauwels","year":"1999","journal-title":"N Engl J Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1136\/bmj.320.7245.1297","volume":"320","author":"Burge","year":"2000","journal-title":"BMJ"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Lung Health Study Research Group. Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease. N Engl J Med. 2000;343:1902\u20131909.","DOI":"10.1056\/NEJM200012283432601"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/S0140-6736(05)66456-2","volume":"365","author":"Decramer","year":"2005","journal-title":"Lancet"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1056\/NEJMoa0805800","volume":"359","author":"Tashkin","year":"2008","journal-title":"N Engl J Med"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1164\/rccm.200712-1869OC","volume":"178","author":"Celli","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2147\/COPD.S27480","volume":"7","author":"Tantucci","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1164\/rccm.201105-0831OC","volume":"184","author":"Casanova","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1164\/rccm.202005-1854OC","volume":"203","author":"Celli","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1164\/rccm.200703-456SO","volume":"176","author":"Rabe","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1700214","DOI":"10.1183\/13993003.00214-2017","volume":"49","author":"Vogelmeier","year":"2017","journal-title":"Eur Respir J"},{"key":"ref19","unstructured":"Global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; 2019. Available From: https:\/\/goldcopd.org\/wp-content\/uploads\/2018\/11\/GOLD-2019-v1.7-FINAL-14Nov2018-WMS.pdf. Accessed August 18, 2021."},{"key":"ref20","unstructured":"Global Strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; 2020. Available From: https:\/\/goldcopd.org\/wp-content\/uploads\/2019\/11\/GOLD-2020-REPORT-ver1.0wms.pdf. Accessed August 18, 2021."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1183\/23120541.00132-2017","volume":"4","author":"Celli","year":"2018","journal-title":"ERJ Open Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMoa1411532","volume":"373","author":"Lange","year":"2015","journal-title":"N Engl J Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/S2213-2600(17)30434-4","volume":"5","author":"Agust\u00ed","year":"2017","journal-title":"Lancet Respir Med"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1800263","DOI":"10.1183\/13993003.00263-2018","volume":"51","author":"Singh","year":"2018","journal-title":"Eur Respir J"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s41030-019-0090-1","volume":"5","author":"D\u2019Urzo","year":"2019","journal-title":"Pulm Ther"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12931-017-0548-3","volume":"18","author":"Miravitlles","year":"2017","journal-title":"Respir Res"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1378\/chest.10-2521","volume":"140","author":"Waschki","year":"2011","journal-title":"Chest"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1801219","DOI":"10.1183\/13993003.01219-2018","volume":"52","author":"Agusti","year":"2018","journal-title":"Eur Respir J"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1183\/09031936.00.15110900","volume":"15","author":"Rutgers","year":"2000","journal-title":"Eur Respir J"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.jaci.2017.04.027","volume":"140","author":"Kolsum","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0140-6736(00)02872-5","volume":"356","author":"Brightling","year":"2000","journal-title":"Lancet"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S2213-2600(18)30006-7","volume":"6","author":"Bafadhel","year":"2018","journal-title":"Lancet Respir Med"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1183\/09031936.00162414","volume":"1","author":"Singh","year":"2014","journal-title":"Eur Respir J"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1701162","DOI":"10.1183\/13993003.01162-2017","volume":"50","author":"Casanova","year":"2017","journal-title":"Eur Respir J"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1800427","DOI":"10.1183\/13993003.00427-2018","volume":"52","author":"Southworth","year":"2018","journal-title":"Eur Respir J"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/S0140-6736(18)30206-X","volume":"391","author":"Papi","year":"2018","journal-title":"Lancet"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1183\/13993003.02165-2015","volume":"48","author":"Pascoe","year":"2016","journal-title":"Eur Respir J"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1056\/NEJMoa1713901","volume":"378","author":"Lipson","year":"2018","journal-title":"N Engl J Med"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1056\/NEJMoa1916046","volume":"383","author":"Rabe","year":"2020","journal-title":"N Engl J Med"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1056\/NEJMoa1516385","volume":"374","author":"Wedzicha","year":"2016","journal-title":"N Engl J Med"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S2213-2600(18)30102-4","volume":"6","author":"Calverley","year":"2018","journal-title":"Lancet Respir Med"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2147\/COPD.S189138","volume":"14","author":"Sethi","year":"2019","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1001\/jama.2019.4973","volume":"321","author":"Wise","year":"2019","journal-title":"JAMA"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1183\/09031936.00208613","volume":"44","author":"Sanchez-Salcedo","year":"2014","journal-title":"Eur Respir J"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S2213-2600(17)30119-4","volume":"5","author":"\u00c7olak","year":"2017","journal-title":"Lancet Respir Med"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S0140-6736(09)61290-3","volume":"374","author":"Soriano","year":"2009","journal-title":"Lancet"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1164\/rccm.201509-1795OC","volume":"194","author":"Labonte","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1513\/AnnalsATS.201506-388OC","volume":"12","author":"Martinez","year":"2015","journal-title":"Ann Am Thorac Soc"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1164\/rccm.201603-0622OC","volume":"195","author":"Martinez","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S2213-2600(18)30529-0","volume":"7","author":"Agusti","year":"2019","journal-title":"Lancet Respir Med"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1900217","DOI":"10.1183\/13993003.00217-2019","volume":"53","author":"Agusti","year":"2019","journal-title":"Eur Respir J"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1136\/thoraxjnl-2017-210842","volume":"73","author":"Oelsner","year":"2018","journal-title":"Thorax"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1164\/rccm.201511-2210OC","volume":"193","author":"Allinson","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1164\/rccm.201805-0861LE","volume":"198","author":"Petersen","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1164\/rccm.202008-3328PP","volume":"203","author":"Han","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1183\/13993003.01359-2015","volume":"47","author":"Agusti","year":"2016","journal-title":"Eur Respir J"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/S0140-6736(19)30950-X","volume":"393","author":"Dransfield","year":"2019","journal-title":"Lancet"}],"container-title":["International Journal of Chronic Obstructive Pulmonary Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=83656","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=83656","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T23:50:48Z","timestamp":1662421848000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/new-perspectives-on-chronic-obstructive-pulmonary-disease-peer-reviewed-fulltext-article-COPD"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":57,"URL":"https:\/\/doi.org\/10.2147\/copd.s365771","relation":{},"ISSN":["1178-2005"],"issn-type":[{"value":"1178-2005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9]]}}}