{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:05:27Z","timestamp":1790870727121,"version":"4.1.0"},"reference-count":45,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["COPD"],"DOI":"10.2147\/copd.s513350","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T10:45:11Z","timestamp":1747997111000},"page":"1651-1663","source":"Crossref","is-referenced-by-count":4,"title":["Managing Small Airways Dysfunction in COPD Patients in Real Life Under Fixed Triple Combination of Beclomethasone\/Formoterol\/Glycopyrronium: The MASCOT Real World Evidence Study"],"prefix":"10.2147","volume":"Volume 20","author":[{"given":"Athena","family":"Gogali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-3942","authenticated-orcid":true,"given":"Konstantinos","family":"Kostikas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8806-2561","authenticated-orcid":true,"given":"Christos","family":"Kyriakopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6175-8036","authenticated-orcid":true,"given":"Dimitrios","family":"Potonos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Porpodis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioanna","family":"Tsiouprou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4456-8987","authenticated-orcid":true,"given":"Evangelia","family":"Fouka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Tryfon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2415-0842","authenticated-orcid":true,"given":"Efthymia","family":"Papadopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Kipourou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Katsoulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/S2213-2600(21)00555-5","volume":"10","author":"Agust\u00ed","year":"2022","journal-title":"Lancet Respir Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e2346598","DOI":"10.1001\/jamanetworkopen.2023.46598","volume":"6","author":"Boers","year":"2023","journal-title":"JAMA Network Open"},{"key":"ref3","unstructured":"2025 GOLD report [Internet]. Global Initiative for Chronic Obstructive Lung Disease \u2013 GOLD; 2024 [cited 2024 Dec 9]. Available from: https:\/\/goldcopd.org\/2025-gold-report\/. Accessed May 20, 2025."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2451613","DOI":"10.1080\/15412555.2025.2451613","volume":"22","author":"Kostikas","year":"2025","journal-title":"COPD"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00816-2020","volume":"7","author":"Halpin","year":"2021","journal-title":"ERJ Open Res"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"2000881","DOI":"10.1183\/13993003.00881-2020","volume":"55","author":"Stolz","year":"2020","journal-title":"Eur Respir J"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1056\/NEJMoa1713901","volume":"378","author":"Lipson","year":"2018","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/S0140-6736(16)31354-X","volume":"388","author":"Singh","year":"2016","journal-title":"Lancet"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1056\/NEJMoa1916046","volume":"383","author":"Rabe","year":"2020","journal-title":"N Engl J Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1056\/NEJMe1110635","volume":"365","author":"Mitzner","year":"2011","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1056\/NEJMoa1106955","volume":"365","author":"McDonough","year":"2011","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1080\/17476348.2024.2380070","volume":"18","author":"Lazarinis","year":"2024","journal-title":"Expert Rev Respir Med"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1159\/000452479","volume":"93","author":"Crisafulli","year":"2017","journal-title":"Respiration"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/S2213-2600(17)30207-2","volume":"5","author":"Han","year":"2017","journal-title":"Lancet Respir Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.1016\/j.rmed.2013.05.003","volume":"119","author":"Katsoulis","year":"2016","journal-title":"Respir Med"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.anai.2017.04.009","volume":"118","author":"Galant","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1089\/jamp.2020.1601","volume":"34","author":"Usmani","year":"2021","journal-title":"J Aerosol Med Pulm Drug Deliv"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1016\/S0140-6736(17)30188-5","volume":"389","author":"Vestbo","year":"2017","journal-title":"Lancet"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1016\/S0140-6736(18)30206-X","volume":"391","author":"Papi","year":"2018","journal-title":"Lancet"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1183\/13993003.01708-2015","volume":"47","author":"Contoli","year":"2016","journal-title":"Eur Respir J"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s41030-021-00144-x","volume":"7","author":"Pisi","year":"2021","journal-title":"Pulm Ther"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"475","DOI":"10.2147\/COPD.S445858","volume":"19","author":"Richeldi","year":"2024","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"3019","DOI":"10.2147\/COPD.S382405","volume":"17","author":"Gessner","year":"2022","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"106398","DOI":"10.1016\/j.rmed.2021.106398","volume":"182","author":"Marth","year":"2021","journal-title":"Respir Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"17534666241263439","DOI":"10.1177\/17534666241263439","volume":"18","author":"Steiropoulos","year":"2024","journal-title":"Ther Adv Respir Dis"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"107219","DOI":"10.1016\/j.rmed.2023.107219","volume":"212","author":"Porpodis","year":"2023","journal-title":"Respir Med"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1183\/09031936.00102509","volume":"34","author":"Jones","year":"2009","journal-title":"Eur Respir J"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(06)80166-6","volume":"85","author":"Jones","year":"1991","journal-title":"Respir Med"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1081\/COPD-200050513","volume":"2","author":"Jones","year":"2005","journal-title":"COPD"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S2213-2600(14)70001-3","volume":"2","author":"Kon","year":"2014","journal-title":"Lancet Respir Med"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1136\/thoraxjnl-2020-216037","volume":"76","author":"Polosukhin","year":"2021","journal-title":"Thorax"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1164\/rccm.201511-2219OC","volume":"194","author":"Bhatt","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1471-2466-10-10","volume":"10","author":"Haruna","year":"2010","journal-title":"BMC Pulm Med"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"2433","DOI":"10.2147\/COPD.S269001","volume":"15","author":"Usmani","year":"2020","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"85","DOI":"10.37349\/eaa.2024.00031","author":"Kraemer","year":"2024","journal-title":"Explor Asthma Allergy"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.rmed.2011.01.010","volume":"105","author":"Crim","year":"2011","journal-title":"Respir Med"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"897","DOI":"10.2147\/COPD.S129974","volume":"12","author":"Liu","year":"2017","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1016\/j.rmed.2012.04.010","volume":"106","author":"Frantz","year":"2012","journal-title":"Respir Med"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s12931-021-01662-7","volume":"22","author":"Li","year":"2021","journal-title":"Respir Res"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.jaip.2019.06.035","volume":"8","author":"Chiu","year":"2020","journal-title":"J Allergy Clin Immunol Pract"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s40248-017-0105-4","volume":"12","author":"Molino","year":"2017","journal-title":"Multidiscip Respir Med"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s00408-015-9839-y","volume":"194","author":"Manoharan","year":"2016","journal-title":"Lung"},{"key":"ref43","first-page":"1831","volume":"15","author":"Kostikas","year":"2020","journal-title":"Int J Chronic Obstr"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1702681","DOI":"10.1183\/13993003.02681-2017","volume":"51","author":"\u00c7olak","year":"2018","journal-title":"Eur Respir J"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"e002142","DOI":"10.1136\/bmjresp-2023-002142","volume":"11","author":"Kraemer","year":"2024","journal-title":"BMJ Open Respir Res"}],"container-title":["International Journal of Chronic Obstructive Pulmonary Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/103239","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/103239","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T10:45:14Z","timestamp":1747997114000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/managing-small-airways-dysfunction-in-copd-patients-in-real-life-under-peer-reviewed-fulltext-article-COPD"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":45,"URL":"https:\/\/doi.org\/10.2147\/copd.s513350","relation":{},"ISSN":["1178-2005"],"issn-type":[{"value":"1178-2005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]}}}