{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:16:37Z","timestamp":1792844197872,"version":"4.5.0"},"reference-count":0,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s154922","type":"journal-article","created":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T21:23:21Z","timestamp":1537737801000},"page":"3147-3161","source":"Crossref","is-referenced-by-count":47,"title":["Profile of asfotase alfa in the treatment of hypophosphatasia: design, development, and place in therapy"],"prefix":"10.2147","volume":"Volume 12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6917-5333","authenticated-orcid":true,"given":"Sasigarn A.","family":"Bowden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian L.","family":"Foster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2018,9]]},"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=44674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=44674","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T21:23:22Z","timestamp":1537737802000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/profile-of-asfotase-alfa-in-the-treatment-of-hypophosphatasia-design-d-peer-reviewed-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.2147\/dddt.s154922","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}