{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:46:05Z","timestamp":1758401165480,"version":"3.40.5"},"reference-count":29,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s258173","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T21:21:36Z","timestamp":1596489696000},"page":"3131-3142","source":"Crossref","is-referenced-by-count":2,"title":["&lt;p&gt;Bioequivalence Study of Amitriptyline Hydrochloride Tablets in Healthy Chinese Volunteers Under Fasting and Fed Conditions&lt;\/p&gt;"],"prefix":"10.2147","volume":"Volume 14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-1462","authenticated-orcid":true,"given":"You","family":"Zhai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunliang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minglan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujie","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6409-709X","authenticated-orcid":true,"given":"Qian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianzhong","family":"Shentu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingwei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6882-0468","authenticated-orcid":true,"given":"Jian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,8]]},"reference":[{"key":"ref1","unstructured":"World Health Organization. Depression and other common mental disorders: global health estimates. License: CC BY-NC-SA 3.0 IGO; 2017. Available from: http:\/\/www.who.int\/iris\/handle\/10665\/254610. Accessed March 1, 2019."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1159\/000447034","volume":"85","author":"Carvalho","year":"2016","journal-title":"Psychother Psychosom"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1037\/a0038550","volume":"23","author":"Hillhouse","year":"2015","journal-title":"Exp Clin Psychopharmacol"},{"key":"ref4","first-page":"1","volume":"76","author":"Pratt","year":"2011","journal-title":"NCHS Data Brief"},{"key":"ref5","unstructured":"National Center for Health Statistics. Health, United States, 2010: With Special Feature on Death and Dying. Table 95. Hyattsville, MD; 2011."},{"journal-title":"Cochrane Database Syst Rev","year":"2007","author":"Vezmar","key":"ref6"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1192\/bjp.178.2.129","volume":"178","author":"Barbui","year":"2001","journal-title":"Br J Psychiatry"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1093\/ijnp\/pyz062","volume":"23","author":"Cheng","year":"2020","journal-title":"Int J Neuropsychopharmacol"},{"key":"ref9","unstructured":"Thour A, Marwaha R. Amitriptyline. 2020 Apr 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan\u2013. PMID: 30725910."},{"volume-title":"Arzneiverordnungsreport 2009","year":"2009","key":"ref10"},{"key":"ref11","unstructured":"Personal communication. GPRD. Available from: http:\/\/www.gprd.com\/2011. Accessed July 21, 2020."},{"key":"ref12","unstructured":"WHO Expert Committee. The selection and use of essential medicines. World Health Organ Tech Rep Ser. 2014;985:i\u2013xiv, 1\u2013219, back cover."},{"key":"ref13","unstructured":"Chinese national essential drug catalogue (basic medical and health institutions). China; 2018. Available from: http:\/\/www.nhc.gov.cn\/wjw\/jbywml\/201810\/600865149f4740eb8ebe729c426fb5d7.shtml. Accessed July 21, 2020."},{"key":"ref14","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1081\/DMR-200033482","volume":"36","author":"Breyer-Pfaff","year":"2004","journal-title":"Drug Metab Rev"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1007\/BF00178516","volume":"88","author":"Kr\u00fcger","year":"1986","journal-title":"Psychopharmacology (Berl)"},{"key":"ref16","unstructured":"UpToDate. Tricyclic and tetracyclic drugs: pharmacology, administration, and side effects; 2016 [cited August 2, 2016]. Available from: https:\/\/www.uptodate.com\/contents\/tricyclic-and-tetracyclic-drugs-pharmacology-administration-andsideeffects?source=machineLearning&search=tricyclic+antidepressants&selectedTitle=1\uff5e150&sectionRank=2&anchor=H31-references. Accessed July 21, 2020."},{"key":"ref17","first-page":"CD008242","volume":"2015","author":"Moore","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1213\/ANE.0000000000002352","volume":"125","author":"Hiroki","year":"2017","journal-title":"Anesth Analg"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1586\/14737175.2015.1091726","volume":"15","author":"Rico-Villademoros","year":"2015","journal-title":"Expert Rev Neurother"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1159\/000080960","volume":"50","author":"Rampello","year":"2004","journal-title":"Neuropsychobiology"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s11940-019-0557-2","volume":"21","author":"Burch","year":"2019","journal-title":"Curr Treat Options Neurol"},{"key":"ref22","unstructured":"AMITRIPTYLINE HYDROCHLORIDE-amitriptyline hydrochloride tablet, film coated. Durham, NC: Inc, A.H.; 2016. Available from: https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=1e6d2c80-fbc8-444e-bdd3-6a91fe1b95bd. Accessed July 21, 2020."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1038\/clpt.2013.2","volume":"93","author":"Hicks","year":"2013","journal-title":"Clin Pharmacol Ther"},{"key":"ref24","unstructured":"Draft Guidance on Amitriptyline Hydrochloride. US Food and Drug Administration. USA. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/psg\/Amitriptyline_HCl_tab_85966_85969_85968_85971_85967_85970_RC3-10.pdf. Accessed March 2010."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.clinthera.2014.09.010","volume":"37","author":"Nam","year":"2015","journal-title":"Clin Ther"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/BF00431754","volume":"74","author":"Burch","year":"1981","journal-title":"Psychopharmacology (Berl)"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1021\/js960085v","volume":"86","author":"Charman","year":"1997","journal-title":"J Pharm Sci"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1002\/jps.21511","volume":"98","author":"Bae","year":"2009","journal-title":"J Pharm Sci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1002\/cpt19782415","volume":"24","author":"McLean","year":"1978","journal-title":"Clin Pharmacol Ther"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=60283","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=60283","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T21:21:43Z","timestamp":1596489703000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/bioequivalence-study-of-amitriptyline-hydrochloride-tablets-in-healthy-peer-reviewed-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":29,"URL":"https:\/\/doi.org\/10.2147\/dddt.s258173","relation":{},"ISSN":["1177-8881"],"issn-type":[{"type":"electronic","value":"1177-8881"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}