{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T14:01:55Z","timestamp":1773842515356,"version":"3.50.1"},"reference-count":28,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s351092","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T12:00:09Z","timestamp":1654516809000},"page":"1713-1729","source":"Crossref","is-referenced-by-count":29,"title":["Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics"],"prefix":"10.2147","volume":"Volume 16","author":[{"given":"Yan","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuiyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3215-4157","authenticated-orcid":true,"given":"Yuhua","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quanfang","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"105671","DOI":"10.1016\/j.intimp.2019.05.056","volume":"75","author":"Du","year":"2019","journal-title":"Int Immunopharmacol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s40659-019-0241-8","volume":"52","author":"Wang","year":"2019","journal-title":"Biol Res"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1186\/s12870-019-1798-7","volume":"19","author":"Yu","year":"2019","journal-title":"BMC Plant Biol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1186\/s12864-019-6309-6","volume":"20","author":"Jia","year":"2019","journal-title":"BMC Genom"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"2985","DOI":"10.1016\/j.celrep.2018.07.068","volume":"24","author":"Han","year":"2018","journal-title":"Cell Rep"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00011-014-0772-y","volume":"64","author":"Li","year":"2015","journal-title":"Inflam Res"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"550","DOI":"10.4254\/wjh.v5.i10.550","volume":"5","author":"Zambo","year":"2013","journal-title":"World J Hepatol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"158658","DOI":"10.1016\/j.bbalip.2020.158658","volume":"1865","author":"Buechler","year":"2020","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.cca.2020.11.026","volume":"513","author":"Wang","year":"2021","journal-title":"Clin Chim Acta"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"113021","DOI":"10.1016\/j.jep.2020.113021","volume":"264","author":"Zhou","year":"2020","journal-title":"J Ethnopharmacol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1007\/s00709-012-0431-5","volume":"250","author":"Sikander","year":"2013","journal-title":"Protoplasma"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"107003","DOI":"10.1016\/j.intimp.2020.107003","volume":"88","author":"Feng","year":"2020","journal-title":"Int Immunopharmacol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"107716","DOI":"10.1016\/j.celrep.2020.107716","volume":"31","author":"Huckins","year":"2020","journal-title":"Cell Rep"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"2667","DOI":"10.2147\/DDDT.S210797","volume":"13","author":"Wu","year":"2019","journal-title":"Drug Des Devel Ther"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1053\/j.gastro.2017.12.022","volume":"154","author":"Du","year":"2018","journal-title":"Gastroenterology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"5511019","DOI":"10.1155\/2021\/5511019","volume":"2021","author":"Li","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"3369","DOI":"10.1038\/s41467-018-05548-z","volume":"9","author":"Yu","year":"2018","journal-title":"Nat Commun"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"9922292","DOI":"10.1155\/2021\/9922292","volume":"2021","author":"Zhou","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"3067","DOI":"10.1021\/acs.jproteome.9b00185","volume":"18","author":"Ferrarini","year":"2019","journal-title":"J Proteome Res"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1039\/d0fo02501a","volume":"12","author":"Sharma","year":"2021","journal-title":"Food Funct"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"H828","DOI":"10.1152\/ajpheart.00752.2012","volume":"304","author":"Roe","year":"2013","journal-title":"Am J Physiol Heart Circul Physiol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2750","DOI":"10.18632\/aging.202325","volume":"13","author":"Long","year":"2020","journal-title":"Aging"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"4310475","DOI":"10.1155\/2017\/4310475","volume":"2017","author":"Yun","year":"2017","journal-title":"Oxid Med Cell Longev"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1053\/j.gastro.2015.09.039","volume":"150","author":"Koo","year":"2016","journal-title":"Gastroenterology"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"967","DOI":"10.3892\/ijmm.2018.4031","volume":"43","author":"Xu","year":"2019","journal-title":"Int J Mol Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.2147\/DDDT.S194787","volume":"13","author":"Wang","year":"2019","journal-title":"Drug Des Devel Ther"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"172946","DOI":"10.1016\/j.ejphar.2020.172946","volume":"876","author":"Liu","year":"2020","journal-title":"Eur J Pharmacol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"436","DOI":"10.4254\/wjh.v12.i8.436","volume":"12","author":"Kartsoli","year":"2020","journal-title":"World J Hepatol"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=81275","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=81275","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T12:00:27Z","timestamp":1654516827000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/didymin-ameliorates-liver-fibrosis-by-alleviating-endoplasmic-reticulu-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":28,"URL":"https:\/\/doi.org\/10.2147\/dddt.s351092","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]}}}