{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:45:15Z","timestamp":1786733115450,"version":"build-2736575974"},"reference-count":41,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s392535","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T08:10:21Z","timestamp":1676880621000},"page":"535-550","source":"Crossref","is-referenced-by-count":19,"title":["Andrographolide Inhibits Static Mechanical Pressure-Induced Intervertebral Disc Degeneration via the MAPK\/Nrf2\/HO-1 Pathway"],"prefix":"10.2147","volume":"Volume 17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5320-036X","authenticated-orcid":true,"given":"Cunxin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoliang","family":"Lyu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dechun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.joca.2018.08.021","volume":"27","author":"Ma","year":"2019","journal-title":"Osteoarthritis Cartilage"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/s41584-020-00568-w","volume":"17","author":"Binch","year":"2021","journal-title":"Nat Rev Rheumatol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1016\/S0140-6736(18)30488-4","volume":"391","author":"Buchbinder","year":"2018","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/S0140-6736(21)00733-9","volume":"398","author":"Knezevic","year":"2021","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"112170","DOI":"10.1016\/j.biopha.2021.112170","volume":"143","author":"Zhang","year":"2021","journal-title":"Biomed Pharmacother"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1038\/s41551-019-0458-4","volume":"3","author":"Bonnevie","year":"2019","journal-title":"Nat Biomed Eng"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1126\/scitranslmed.aau0670","volume":"10","author":"Gullbrand","year":"2018","journal-title":"Sci Transl Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.jmbbm.2018.01.012","volume":"79","author":"Schmidt","year":"2018","journal-title":"J Mech Behav Biomed Mater"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"6699326","DOI":"10.1155\/2021\/6699326","volume":"2021","author":"Wang","year":"2021","journal-title":"Oxid Med Cell Longev"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20180018","volume":"38","author":"Fang","year":"2018","journal-title":"Biosci Rep"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2147\/JPR.S349251","volume":"15","author":"Tarabeih","year":"2022","journal-title":"J Pain Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00441-019-03136-1","volume":"379","author":"Molladavoodi","year":"2020","journal-title":"Cell Tissue Res"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1002\/ptr.6339","volume":"33","author":"Hancke","year":"2019","journal-title":"Phytother Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1111\/jocd.13161","volume":"19","author":"Cantelli","year":"2020","journal-title":"J Cosmet Dermatol"},{"key":"ref15","first-page":"S41","volume":"98","author":"Phunikhom","year":"2015","journal-title":"J Med Assoc Thai"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1002\/ptr.5361","volume":"29","author":"Wen","year":"2015","journal-title":"Phytother Res"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/s12883-020-01745-w","volume":"20","author":"Ciampi","year":"2020","journal-title":"BMC Neurol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3390\/ijms22094642","volume":"22","author":"Juan","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/s41586-019-1485-8","volume":"573","author":"Solis","year":"2019","journal-title":"Nature"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1038\/s41467-021-21178-4","volume":"12","author":"Jiang","year":"2021","journal-title":"Nat Commun"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"8884922","DOI":"10.1155\/2021\/8884922","volume":"2021","author":"Wang","year":"2021","journal-title":"Oxid Med Cell Longev"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1744","DOI":"10.1111\/bph.14188","volume":"175","author":"Evans","year":"2018","journal-title":"Br J Pharmacol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1080\/10408398.2018.1501657","volume":"59","author":"Dai","year":"2019","journal-title":"Crit Rev Food Sci Nutr"},{"key":"ref24","first-page":"3","volume":"10","author":"Ryter","year":"2021","journal-title":"Cells-Basel"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1164\/rccm.200404-465SO","volume":"172","author":"Morse","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"102170","DOI":"10.1016\/j.redox.2021.102170","volume":"47","author":"Wu","year":"2021","journal-title":"Redox Biol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1179\/135100009X392584","volume":"14","author":"Li","year":"2009","journal-title":"Redox Rep"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1016\/j.spinee.2017.03.015","volume":"17","author":"Zhang","year":"2017","journal-title":"Spine J"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1002\/ejhf.1320","volume":"21","author":"van der Pol","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.redox.2012.10.001","volume":"1","author":"Kansanen","year":"2013","journal-title":"Redox Biol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1101\/gad.13.1.76","volume":"13","author":"Itoh","year":"1999","journal-title":"Genes Dev"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.1038\/s41418-019-0303-z","volume":"26","author":"Zhang","year":"2019","journal-title":"Cell Death Differ"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"e2531","DOI":"10.1038\/cddis.2016.443","volume":"8","author":"Ugun-Klusek","year":"2017","journal-title":"Cell Death Dis"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1152\/physrev.00023.2017","volume":"98","author":"Yamamoto","year":"2018","journal-title":"Physiol Rev"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.canlet.2012.06.007","volume":"325","author":"Tian","year":"2012","journal-title":"Cancer Lett"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1210\/edrv.22.2.0428","volume":"22","author":"Pearson","year":"2001","journal-title":"Endocr Rev"},{"key":"ref37","first-page":"7","volume":"9","author":"Park","year":"2020","journal-title":"Antioxidants"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"15087","DOI":"10.1038\/s41598-019-51614-x","volume":"9","author":"Han","year":"2019","journal-title":"Sci Rep"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3390\/nu12061742","volume":"12","author":"Huang","year":"2020","journal-title":"Nutrients"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1080\/15548627.2017.1345411","volume":"13","author":"Mildenberger","year":"2017","journal-title":"Autophagy"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1080\/15548627.2019.1644076","volume":"16","author":"Deng","year":"2020","journal-title":"Autophagy"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=87626","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=87626","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T17:12:43Z","timestamp":1728925963000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/andrographolide-inhibits-static-mechanical-pressure-induced-interverte-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":41,"URL":"https:\/\/doi.org\/10.2147\/dddt.s392535","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2]]}}}