{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T19:06:42Z","timestamp":1776712002012,"version":"3.51.2"},"reference-count":50,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s403087","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T04:05:09Z","timestamp":1690257909000},"page":"2183-2192","source":"Crossref","is-referenced-by-count":8,"title":["Probiotics Alleviate Chemotherapy-Associated Intestinal Mucosal Injury via the TLR4\u2013NF\u03baB Signaling Pathway"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Xiaochong","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bowen","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiachen","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxiang","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingjuan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqing","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Qiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2023,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/SPC.0b013e32832531bb","volume":"3","author":"Gibson","year":"2009","journal-title":"Curr Opin Support Palliat Care"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJMoa043330","volume":"352","author":"Stupp","year":"2005","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.1073\/pnas.96.7.3911","volume":"96","author":"Toft","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/hed.10318","volume":"25","author":"Scully","year":"2003","journal-title":"Head Neck"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/SPC.0000000000000202","volume":"10","author":"Cario","year":"2016","journal-title":"Curr Opin Support Palliat Care"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1258\/ebm.2012.012260","volume":"238","author":"Thorpe","year":"2013","journal-title":"Exp Biol Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.33549\/physiolres.932948","volume":"65","author":"Kim","year":"2016","journal-title":"Physiol Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.cyto.2016.04.012","volume":"83","author":"Xiao","year":"2016","journal-title":"Cytokine"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s00280-016-3139-y","volume":"78","author":"Ribeiro","year":"2016","journal-title":"Cancer Chemother Pharmacol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/ncponc1021","volume":"5","author":"Herrstedt","year":"2008","journal-title":"Nat Clin Pract Oncol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"4472","DOI":"10.1200\/JCO.2006.05.6382","volume":"24","author":"Bloechl-Daum","year":"2006","journal-title":"J Clin Oncol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"188494","DOI":"10.1016\/j.bbcan.2020.188494","volume":"1875","author":"Badgeley","year":"2021","journal-title":"Biochimica Et Biophysica Acta Rev Cancer"},{"key":"ref13","unstructured":"FAO\/WHO. Joint FAO\/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk and Live Lactic Acid Bacteria. Food and Agriculture Organization of the United Nations (FAO)\/World Health Organization (WHO); 2001."},{"key":"ref14","doi-asserted-by":"crossref","first-page":"393s","DOI":"10.1093\/ajcn\/73.2.393s","volume":"73","author":"Tuomola","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3390\/toxics9030056","volume":"9","author":"Chen","year":"2021","journal-title":"Toxics"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"131374","DOI":"10.1016\/j.chemosphere.2021.131374","volume":"284","author":"Hu","year":"2021","journal-title":"Chemosphere"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"8164","DOI":"10.1021\/acs.jafc.2c08076","volume":"71","author":"Bai","year":"2023","journal-title":"J Agric Food Chem"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e0261189","DOI":"10.1371\/journal.pone.0261189","volume":"16","author":"Panpetch","year":"2021","journal-title":"PLoS One"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s13568-020-00980-1","volume":"10","author":"Shonyela","year":"2020","journal-title":"AMB Express"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"112514","DOI":"10.1016\/j.fct.2021.112514","volume":"156","author":"Bai","year":"2021","journal-title":"Food Chem Toxicol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/MPG.0b013e3181924d1e","volume":"49","author":"Lu","year":"2009","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1136\/gutjnl-2011-300367","volume":"61","author":"Ciorba","year":"2012","journal-title":"Gut"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1093\/ajcn\/80.6.1618","volume":"80","author":"Braat","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/0016-5085(93)91059-Q","volume":"105","author":"Isolauri","year":"1993","journal-title":"Gastroenterology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.jmii.2015.05.002","volume":"50","author":"Gao","year":"2017","journal-title":"J Microbiol Immunol Infection"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/lam.13255","volume":"70","author":"Qi","year":"2020","journal-title":"Lett Appl Microbiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/MCG.0000000000001170","volume":"53","author":"Capurso","year":"2019","journal-title":"J Clin Gastroenterol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"e0184250","DOI":"10.1371\/journal.pone.0184250","volume":"12","author":"Feldman","year":"2017","journal-title":"PLoS One"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"867","DOI":"10.3390\/nu10111698","volume":"10","author":"Orlando","year":"2018","journal-title":"Nutrients"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.2147\/DDDT.S298261","volume":"15","author":"Li","year":"2021","journal-title":"Drug Des Devel Ther"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"e0184360","DOI":"10.1371\/journal.pone.0184360","volume":"12","author":"Pearce","year":"2017","journal-title":"PLoS One"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1002\/cncr.11671","volume":"98","author":"Elting","year":"2003","journal-title":"Cancer"},{"key":"ref33","first-page":"38","volume":"12","author":"Anderson","year":"2020","journal-title":"Nutrients"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"e0161337","DOI":"10.1371\/journal.pone.0161337","volume":"11","author":"Petrova","year":"2016","journal-title":"PLoS One"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3109\/00365521.2014.898326","volume":"49","author":"Helander","year":"2014","journal-title":"Scand J Gastroenterol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1007\/s00520-020-05762-w","volume":"29","author":"Andersen","year":"2021","journal-title":"Support Care Cancer"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"5003","DOI":"10.3168\/jds.2019-17836","volume":"103","author":"Hu","year":"2020","journal-title":"J Dairy Sci"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/gutjnl-2012-302167","volume":"62","author":"Simr\u00e9n","year":"2013","journal-title":"Gut"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.2527\/jas.2006-076","volume":"84","author":"Bikker","year":"2006","journal-title":"J Anim Sci"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"7945","DOI":"10.1128\/AEM.02507-15","volume":"81","author":"De Angelis","year":"2015","journal-title":"Appl Environ Microbiol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/ajcn\/68.1.118","volume":"68","author":"Tappenden","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1111\/nmo.12990","volume":"28","author":"Spencer","year":"2016","journal-title":"Neurogastroenterol Motil"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"G171","DOI":"10.1152\/ajpgi.00048.2015","volume":"312","author":"Wells","year":"2017","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"769","DOI":"10.3945\/jn.110.135657","volume":"141","author":"Ulluwishewa","year":"2011","journal-title":"J Nutr"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3389\/fmicb.2019.00477","volume":"10","author":"Gao","year":"2019","journal-title":"Front Microbiol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1084\/jem.20111453","volume":"209","author":"Coccia","year":"2012","journal-title":"J Exp Med"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"G367","DOI":"10.1152\/ajpgi.00173.2003","volume":"286","author":"Ma","year":"2004","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1080\/15548627.2019.1596495","volume":"15","author":"Jung","year":"2019","journal-title":"Autophagy"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s40104-023-00830-7","volume":"14","author":"Li","year":"2023","journal-title":"J Anim Sci Biotechnol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"551449","DOI":"10.3389\/fimmu.2020.551449","volume":"11","author":"Li","year":"2020","journal-title":"Front Immunol"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=91443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=91443","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T04:05:27Z","timestamp":1690257927000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/probiotics-alleviate-chemotherapy-associated-intestinal-mucosal-injury-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":50,"URL":"https:\/\/doi.org\/10.2147\/dddt.s403087","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7]]}}}