{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T03:24:10Z","timestamp":1785727450494,"version":"3.56.0"},"reference-count":26,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s416325","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T11:55:11Z","timestamp":1689076511000},"page":"2051-2061","source":"Crossref","is-referenced-by-count":13,"title":["Phase I, Single-Dose Study to Assess the Pharmacokinetics and Safety of Suramin in Healthy Chinese Volunteers"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Guolan","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruling","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songxia","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiejing","family":"Kai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nana","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lie","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanfang","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Shentu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/S0140-6736(09)60829-1","volume":"375","author":"Brun","year":"2010","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e62","DOI":"10.1038\/emi.2014.60","volume":"3","author":"Ren","year":"2014","journal-title":"Emerg Microbes Infect"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.antiviral.2017.04.016","volume":"143","author":"Albulescu","year":"2017","journal-title":"Antiviral Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.antiviral.2015.06.013","volume":"121","author":"Albulescu","year":"2015","journal-title":"Antiviral Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"314","DOI":"10.3390\/v12030314","volume":"12","author":"Albulescu","year":"2020","journal-title":"Viruses"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1186\/s12985-016-0607-2","volume":"13","author":"Henss","year":"2016","journal-title":"Virol J"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1038\/s41594-021-00570-0","volume":"28","author":"Yin","year":"2021","journal-title":"Nat Struct Mol Biol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00900-20","volume":"64","author":"Salgado-Benvindo","year":"2020","journal-title":"Antimicrob Agents Chemother"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01168-19","volume":"64","author":"Wiedemar","year":"2020","journal-title":"Antimicrob Agents Chemother"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00280-002-0458-y","volume":"50","author":"Ryan","year":"2002","journal-title":"Cancer Chemother Pharmacol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1023\/a:1015666024386","volume":"20","author":"Kaur","year":"2002","journal-title":"Invest New Drugs"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1200\/JCO.2000.18.7.1440","volume":"18","author":"Small","year":"2000","journal-title":"J Clin Oncol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/s0090-4295(98)00544-5","volume":"53","author":"Garcia-Schurmann","year":"1999","journal-title":"Urology"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"2174","DOI":"10.1200\/JCO.1995.13.9.2174","volume":"13","author":"Eisenberger","year":"1995","journal-title":"J Clin Oncol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"3260","DOI":"10.1200\/JCO.2001.19.13.3260","volume":"19","author":"Grossman","year":"2001","journal-title":"J Clin Oncol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1002\/acn3.424","volume":"4","author":"Naviaux","year":"2017","journal-title":"Ann Clin Transl Neurol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"2196","DOI":"10.1200\/JCO.1995.13.9.2196","volume":"13","author":"Kobayashi","year":"1995","journal-title":"J Clin Oncol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1200\/JCO.1989.7.4.499","volume":"7","author":"Stein","year":"1989","journal-title":"J Clin Oncol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1212\/wnl.40.6.954","volume":"40","author":"La Rocca","year":"1990","journal-title":"Neurology"},{"key":"ref20","first-page":"273","volume":"71","author":"Horne","year":"1988","journal-title":"Blood"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/0305-7372(94)90003-5","volume":"20","author":"Eisenberger","year":"1994","journal-title":"Cancer Treat Rev"},{"key":"ref22","first-page":"64","volume":"52","author":"Scher","year":"1992","journal-title":"Cancer Res"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1200\/JCO.1994.12.1.166","volume":"12","author":"Jodrell","year":"1994","journal-title":"J Clin Oncol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1186\/s12889-021-11198-6","volume":"21","author":"Ye","year":"2021","journal-title":"BMC Public Health"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"873","DOI":"10.3390\/v13050873","volume":"13","author":"Eberle","year":"2021","journal-title":"Viruses"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.antiviral.2013.12.008","volume":"103","author":"Wang","year":"2014","journal-title":"Antiviral Res"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=91098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=91098","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T11:55:16Z","timestamp":1689076516000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/phase-i-single-dose-study-to-assess-the-pharmacokinetics-and-safety-of-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":26,"URL":"https:\/\/doi.org\/10.2147\/dddt.s416325","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7]]}}}