{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:32:47Z","timestamp":1789990367363,"version":"4.0.1"},"reference-count":41,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s417954","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T03:55:05Z","timestamp":1694490905000},"page":"2805-2819","source":"Crossref","is-referenced-by-count":19,"title":["Deciphering the Mechanism of Xijiao Dihuang Decoction in Treating Psoriasis by Network Pharmacology and Experimental Validation"],"prefix":"10.2147","volume":"Volume 17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1255-8197","authenticated-orcid":true,"given":"Yicheng","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqun","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guosheng","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijun","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinglong","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2546161","volume":"2019","author":"Bai","year":"2019","journal-title":"J Immunol Res"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.3ma0217-054rr","volume":"102","author":"Costa","year":"2017","journal-title":"J Leukoc Biol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6656622","volume":"2021","author":"Gong","year":"2021","journal-title":"Biomed Res Int"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23084312","volume":"23","author":"Ikeda","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"113","DOI":"10.2147\/PTT.S293107","volume":"12","author":"De Brandt","year":"2022","journal-title":"Psoriasis"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.jaad.2010.11.046","volume":"66","author":"Shapiro","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1001\/jamadermatol.2020.0024","volume":"156","author":"Vaengebjerg","year":"2020","journal-title":"JAMA Dermatol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1080\/14740338.2022.2003328","volume":"21","author":"Van Lint","year":"2022","journal-title":"Expert Opin Drug Saf"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1038\/aps.2012.105","volume":"33","author":"Yang","year":"2012","journal-title":"Acta Pharmacol Sin"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"629513","DOI":"10.3389\/fphar.2021.629513","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Pharmacol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s13568-020-00986-9","volume":"10","author":"Yang","year":"2020","journal-title":"AMB Express"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1016\/j.biopha.2018.03.094","volume":"103","author":"Wang","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"115522","DOI":"10.1016\/j.jep.2022.115522","volume":"297","author":"Zhang","year":"2022","journal-title":"J Ethnopharmacol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1038\/nchembio.118","volume":"4","author":"Hopkins","year":"2008","journal-title":"Nat Chem Biol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1080\/03639045.2020.1788070","volume":"46","author":"Tao","year":"2020","journal-title":"Drug Dev Ind Pharm"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"113214","DOI":"10.1016\/j.jep.2020.113214","volume":"262","author":"Kuai","year":"2020","journal-title":"J Ethnopharmacol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"5882346","DOI":"10.1155\/2022\/5882346","volume":"2022","author":"Wei","year":"2022","journal-title":"Biomed Res Int"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"e352","DOI":"10.1111\/jdv.14154","volume":"31","author":"Goon","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1758-2946-6-13","volume":"6","author":"Ru","year":"2014","journal-title":"J Cheminform"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"D401","DOI":"10.1093\/nar\/gkt1207","volume":"42","author":"Kuhn","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"W32","DOI":"10.1093\/nar\/gku293","volume":"42","author":"Gfeller","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/nrd.2016.29","volume":"15","author":"Scott","year":"2016","journal-title":"Nat Rev Drug Discov"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/ng.311","volume":"41","author":"Nair","year":"2009","journal-title":"Nat Genet"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222112035","volume":"22","author":"Lee","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"5945","DOI":"10.7150\/thno.28068","volume":"8","author":"Zhao","year":"2018","journal-title":"Theranostics"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"6878026","DOI":"10.1155\/2021\/6878026","volume":"2021","author":"Guohua","year":"2021","journal-title":"Oxid Med Cell Longev"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"108824","DOI":"10.1016\/j.intimp.2022.108824","volume":"109","author":"Zhang","year":"2022","journal-title":"Int Immunopharmacol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1007\/BF02975116","volume":"27","author":"Li","year":"2004","journal-title":"Arch Pharm Res"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"113437","DOI":"10.1016\/j.yexcr.2022.113437","volume":"423","author":"Zheng","year":"2023","journal-title":"Exp Cell Res"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1111\/j.1468-3083.2011.04393.x","volume":"27","author":"Zablotna","year":"2013","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"14410","DOI":"10.1074\/jbc.M111.228130","volume":"286","author":"Jung","year":"2011","journal-title":"J Biol Chem"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"5945128","DOI":"10.1155\/2018\/5945128","volume":"2018","author":"Fei","year":"2018","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/j.jid.2020.07.028","volume":"141","author":"Chen","year":"2021","journal-title":"J Invest Dermatol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1016\/j.ymthe.2017.03.020","volume":"25","author":"Cai","year":"2017","journal-title":"Mol Ther"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1111\/bph.15306","volume":"178","author":"Bian","year":"2021","journal-title":"Br J Pharmacol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.ajps.2022.02.003","volume":"17","author":"Chen","year":"2022","journal-title":"Asian J Pharm Sci"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/nm1162","volume":"11","author":"Sano","year":"2005","journal-title":"Nat Med"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1002\/eji.201545883","volume":"45","author":"Hartwig","year":"2015","journal-title":"Eur J Immunol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1038\/nm.1995","volume":"15","author":"Caruso","year":"2009","journal-title":"Nat Med"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1080\/17425255.2019.1681969","volume":"15","author":"Campanati","year":"2019","journal-title":"Expert Opin Drug Metab Toxicol"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=92706","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=92706","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T03:55:08Z","timestamp":1694490908000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/deciphering-the-mechanism-of-xijiao-dihuang-decoction-in-treating-psor-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":41,"URL":"https:\/\/doi.org\/10.2147\/dddt.s417954","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]}}}