{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:03:39Z","timestamp":1790910219346,"version":"4.1.0"},"reference-count":44,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s423333","type":"journal-article","created":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:20:12Z","timestamp":1695774012000},"page":"2969-2983","source":"Crossref","is-referenced-by-count":11,"title":["How Tongxie-Yaofang Regulates Intestinal Synaptic Plasticity by Activating Enteric Glial Cells and NGF\/TrkA Pathway in Diarrhea-Predominant Irritable Bowel Syndrome Rats"],"prefix":"10.2147","volume":"Volume 17","author":[{"given":"Xiaofang","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengsheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1053\/j.gastro.2016.02.031","volume":"150","author":"Mearin","year":"2016","journal-title":"Gastroenterology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/S2468-1253(20)30217-X","volume":"5","author":"Oka","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1053\/j.gastro.2020.04.014","volume":"160","author":"Sperber","year":"2021","journal-title":"Gastroenterology"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1111\/j.1440-1746.2011.06641.x","volume":"26","author":"Liu","year":"2011","journal-title":"J Gastroenterol Hepatol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"709","DOI":"10.20452\/pamw.16067","volume":"131","author":"Bonetto","year":"2021","journal-title":"Pol Arch Intern Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"968930","DOI":"10.3389\/fnut.2022.968930","volume":"9","author":"Xu","year":"2022","journal-title":"Front Nutr"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"9223","DOI":"10.21037\/apm-21-1612","volume":"10","author":"Chen","year":"2021","journal-title":"Ann Palliat Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"554","DOI":"10.20524\/aog.2019.0428","volume":"32","author":"Hadjivasilis","year":"2019","journal-title":"Ann Gastroenterol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1186\/s12906-019-2749-4","volume":"19","author":"Hou","year":"2019","journal-title":"BMC Complement Altern Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1007\/s10620-008-0444-2","volume":"54","author":"Yang","year":"2009","journal-title":"Dig Dis Sci"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1097\/FBP.0000000000000386","volume":"29","author":"L\u00f3pez-P\u00e9rez","year":"2018","journal-title":"Behav Pharmacol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.jcmgh.2018.11.005","volume":"7","author":"Morales-Soto","year":"2019","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"101","DOI":"10.21315\/mjms2017.24.5.11","volume":"24","author":"Arifin","year":"2017","journal-title":"Malays J Med Sci"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"3617","DOI":"10.1111\/bph.15193","volume":"177","author":"Percie du Sert","year":"2020","journal-title":"Br J Pharmacol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"112811","DOI":"10.1016\/j.biopha.2022.112811","volume":"149","author":"Wu","year":"2022","journal-title":"Biomed Pharmacother"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.3389\/fphar.2020.01210","volume":"11","author":"Li","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1538\/expanim.17-0063","volume":"67","author":"Qi","year":"2018","journal-title":"Exp Anim"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s42836-020-00064-2","volume":"3","author":"Chen","year":"2021","journal-title":"Arthroplasty"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"e13430","DOI":"10.1111\/nmo.13430","volume":"30","author":"Zhang","year":"2018","journal-title":"Neurogastroenterol Motil"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"G912","DOI":"10.1152\/ajpgi.00067.2006","volume":"291","author":"Nasser","year":"2006","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1053\/j.gastro.2019.04.019","volume":"157","author":"Simr\u00e9n","year":"2019","journal-title":"Gastroenterology"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2497430","DOI":"10.1155\/2022\/2497430","volume":"2022","author":"Zhao","year":"2022","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref23","volume-title":"Formulas of Chinese Medicine","year":"2010"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"904657","DOI":"10.3389\/fphar.2022.904657","volume":"13","author":"Liang","year":"2022","journal-title":"Front Pharmacol"},{"key":"ref25","first-page":"245","volume":"40","author":"Lin","year":"2020","journal-title":"J Tradit Chin Med"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"3061","DOI":"10.3390\/nu13093061","volume":"13","author":"Aziz","year":"2021","journal-title":"Nutrients"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"9346","DOI":"10.1523\/JNEUROSCI1663-18.2018","volume":"38","author":"Kulkarni","year":"2018","journal-title":"J Neurosci"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1113\/JP271021","volume":"595","author":"Grubi\u0161i\u0107","year":"2017","journal-title":"J Physiol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1002\/ar.24128","volume":"302","author":"Grundmann","year":"2019","journal-title":"Anat Rec"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.ejphar.2017.11.018","volume":"818","author":"Xu","year":"2018","journal-title":"Eur J Pharmacol"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.1111\/nmo.12577","volume":"27","author":"Fujikawa","year":"2015","journal-title":"Neurogastroenterol Motil"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.13703\/j.0255-2930.20220130-0005","volume":"42","author":"Yang","year":"2022","journal-title":"Zhongguo Zhen Jiu"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"325","DOI":"10.2147\/JIR.S285146","volume":"14","author":"Chen","year":"2021","journal-title":"J Inflamm Res"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/papr.12342","volume":"16","author":"Hirose","year":"2016","journal-title":"Pain Pract"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1213\/01.ane.0000275190.42912.37","volume":"105","author":"Thacker","year":"2007","journal-title":"Anesth Analg"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"13644","DOI":"10.1096\/fj.201901192R","volume":"33","author":"Zhang","year":"2019","journal-title":"FASEB J"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/jnc.14797","volume":"151","author":"Kokotos","year":"2019","journal-title":"J Neurochem"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"4390","DOI":"10.3390\/ijms23084390","volume":"23","author":"Levy","year":"2022","journal-title":"Int J Mol Sci"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"E6983","DOI":"10.1073\/pnas.1517045112","volume":"112","author":"Chen","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.3390\/ijms20061482","volume":"20","author":"Baj","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"6077","DOI":"10.3748\/wjg.v25.i40.6077","volume":"25","author":"Bai","year":"2019","journal-title":"World J Gastroenterol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"96","DOI":"10.3390\/brainsci12010096","volume":"12","author":"Xu","year":"2022","journal-title":"Brain Sci"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1744-8069-2-3","volume":"2","author":"Zhou","year":"2006","journal-title":"Mol Pain"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"3132","DOI":"10.4081\/ejh.2020.3132","volume":"64","author":"Li","year":"2020","journal-title":"Eur J Histochem"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=93108","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/getfile.php?fileID=93108","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T00:20:17Z","timestamp":1695774017000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/how-tongxie-yaofang-regulates-intestinal-synaptic-plasticity-by-activa-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":44,"URL":"https:\/\/doi.org\/10.2147\/dddt.s423333","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]}}}