{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T12:12:01Z","timestamp":1781007121304,"version":"3.54.1"},"reference-count":53,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s464712","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T05:15:12Z","timestamp":1731647712000},"page":"5211-5223","source":"Crossref","is-referenced-by-count":2,"title":["Novel Agonists of Adenosine Receptors in Animal Model of Acute Myocardial Infarction"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Fabricio","family":"Beltrame","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Nascimento-Carlos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3946-4753","authenticated-orcid":true,"given":"Jaqueline","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo","family":"Maia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1196-0149","authenticated-orcid":true,"given":"Tadeu","family":"Montagnoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1759-0038","authenticated-orcid":true,"given":"Eliezer","family":"Barreiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5168-8456","authenticated-orcid":true,"given":"Gisele","family":"Zapata-Sudo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0008-6363(01)00434-5","volume":"53","author":"Frangogiannis","year":"2002","journal-title":"Cardiovasc Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1161\/CIRCRESAHA.116.303577","volume":"119","author":"Prabhu","year":"2016","journal-title":"Circ Res"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","volume":"39","author":"Ibanez","year":"2018","journal-title":"Eur Heart J"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.3390\/cells11091386","volume":"11","author":"Venugopal","year":"2022","journal-title":"Cells"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1161\/CIRCULATIONAHA.123.064155","volume":"148","author":"Alex","year":"2023","journal-title":"Circulation"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1172\/JCI31044","volume":"117","author":"Berk","year":"2007","journal-title":"J Clin Invest"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1093\/ehjcvp\/pvy005","volume":"4","author":"Hoedemaker","year":"2018","journal-title":"Eur Heart J Cardiovasc Pharmacother"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1093\/eurheartj\/ehaa575","volume":"42","author":"Collet","year":"2021","journal-title":"Eur Heart J"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.3390\/jcm9051366","volume":"9","author":"Guieu","year":"2020","journal-title":"J Clin Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1016\/j.jacc.2014.09.017","volume":"64","author":"Amsterdam","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1253\/circj.CJ-18-0063","volume":"82","author":"Anzai","year":"2018","journal-title":"Circ J"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.autrev.2010.07.019","volume":"10","author":"Varani","year":"2010","journal-title":"Autoimmun Rev"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"697","DOI":"10.3390\/ijms18040697","volume":"18","author":"Ravani","year":"2017","journal-title":"Int J Mol Sci"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"e112741","DOI":"10.1371\/journal.pone.0112741","volume":"9","author":"Fuentes","year":"2014","journal-title":"PLoS One"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.drudis.2011.10.007","volume":"17","author":"Fishman","year":"2012","journal-title":"Drug Discov Today"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"4963","DOI":"10.1016\/j.bmcl.2009.07.075","volume":"19","author":"K\u00fcmmerle","year":"2009","journal-title":"Bioorg Med Chem Lett"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"553","DOI":"10.2147\/DDDT.S113289","volume":"11","author":"da Silva","year":"2017","journal-title":"Drug Des Devel Ther"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1517\/13543776.2014.959491","volume":"24","author":"Maia","year":"2014","journal-title":"Expert Opin Ther Pat"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s40360-016-0067-8","volume":"17","author":"Arsyad","year":"2016","journal-title":"BMC Pharmacol Toxicol"},{"key":"ref20","unstructured":"Rocha MD Novos prot\u00f3tipos heteroaril-N-acilidraz\u00f4nicos multialvos planejados para o tratamento da hipertens\u00e3o arterial pulmonar [Thesis]. Universidade Feredal do Rio de Janeiro; 2017. Available from: http:\/\/objdig.ufrj.br\/13\/teses\/870915.pdf. Accessed November 4, 2024."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1097\/00001756-199607080-00023","volume":"7","author":"Janigro","year":"1996","journal-title":"Neuroreport"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1038\/sj.bjp.0707242","volume":"151","author":"Barroso","year":"2007","journal-title":"Br J Pharmacol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1093\/eurheartj\/ehq337","volume":"31","author":"Dickstein","year":"2010","journal-title":"Eur Heart J"},{"key":"ref24","first-page":"558","volume":"120","author":"Kazik","year":"2010","journal-title":"Pol Arch Med Wewn"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s40256-019-00345-5","volume":"19","author":"Reiss","year":"2019","journal-title":"Am J Cardiovasc Drugs"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.ejmech.2012.06.056","volume":"55","author":"Leal","year":"2012","journal-title":"Eur J Med Chem"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1038\/ajh.2010.157","volume":"23","author":"Costa","year":"2010","journal-title":"Am J Hypertens"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.lfs.2013.11.012","volume":"94","author":"da Silva","year":"2014","journal-title":"Life Sci"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"18678","DOI":"10.1074\/jbc.271.31.18678","volume":"271","author":"Liang","year":"1996","journal-title":"J Biol Chem"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1111\/j.1752-8062.2008.00027.x","volume":"1","author":"Chan","year":"2008","journal-title":"Clin Transl Sci"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1172\/JCI117653","volume":"95","author":"Duncker","year":"1995","journal-title":"J Clin Invest"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"18","DOI":"10.2174\/1573403x12666160111125116","volume":"12","author":"Nishat","year":"2016","journal-title":"Curr Cardiol Rev"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1124\/jpet.107.127480","volume":"324","author":"Wan","year":"2008","journal-title":"J Pharmacol Exp Ther"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.bcp.2019.01.022","volume":"163","author":"Wan","year":"2019","journal-title":"Biochem Pharmacol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1006\/jmcc.2001.1510","volume":"34","author":"Zhao","year":"2002","journal-title":"J Mol Cell Cardiol"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1590\/S0066-782X2011005000074","volume":"97","author":"Teixeira","year":"2011","journal-title":"Arq Bras Cardiol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s12964-022-00842-2","volume":"20","author":"Chen","year":"2022","journal-title":"Cell Commun Signal"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.yjmcc.2021.06.005","volume":"159","author":"Paterek","year":"2021","journal-title":"J Mol Cell Cardiol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.bbadis.2006.09.002","volume":"1772","author":"Elahi","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"e23411","DOI":"10.1002\/jbt.23411","volume":"37","author":"Hu","year":"2023","journal-title":"J Biochem Mol Toxicol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"100366","DOI":"10.1016\/j.ijcha.2019.100366","volume":"23","author":"Mahmoud","year":"2019","journal-title":"Int J Cardiol Heart Vasc"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1007\/s11033-010-0137-8","volume":"38","author":"Ke","year":"2011","journal-title":"Mol Biol Rep"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1007\/s11655-020-2856-6","volume":"26","author":"Ma","year":"2020","journal-title":"Chin J Integr Med"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"12401","DOI":"10.1111\/jcmm.15748","volume":"24","author":"Zhai","year":"2020","journal-title":"J Cell Mol Med"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24020270","author":"Ibarra-Lara","year":"2019","journal-title":"Molecules"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.lfs.2014.04.020","volume":"106","author":"Li","year":"2014","journal-title":"Life Sci"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1161\/hc3201.092284","volume":"104","author":"Feng","year":"2001","journal-title":"Circulation"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"H1410","DOI":"10.1152\/ajpheart.00860.2005","volume":"290","author":"Toufektsian","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1172\/JCI146926","volume":"132","author":"Humeres","year":"2022","journal-title":"J Clin Invest"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"9603271221077684","DOI":"10.1177\/09603271221077684","volume":"41","author":"Guo","year":"2022","journal-title":"Hum Exp Toxicol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"18842","DOI":"10.1074\/jbc.M500620200","volume":"280","author":"Tanos","year":"2005","journal-title":"J Biol Chem"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1111\/bph.13339","volume":"173","author":"Puhl","year":"2016","journal-title":"Br J Pharmacol"},{"key":"ref53","first-page":"611","volume":"286","author":"Smits","year":"1998","journal-title":"J Pharmacol Exp Ther"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/97331","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/97331","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T05:15:16Z","timestamp":1731647716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/novel-agonists-of-adenosine-receptors-in-animal-model-of-acute-myocard-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":53,"URL":"https:\/\/doi.org\/10.2147\/dddt.s464712","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}