{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:32:58Z","timestamp":1781307178214,"version":"3.54.1"},"reference-count":9,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s472922","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T02:10:13Z","timestamp":1724119813000},"page":"3659-3666","source":"Crossref","is-referenced-by-count":6,"title":["Treatment of Melasma with Tranexamic Acid Essence Combined with Iontophoresis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial"],"prefix":"10.2147","volume":"Volume 18","author":[{"given":"Linghong","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7620-7323","authenticated-orcid":true,"given":"Xu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingfeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqin","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5109-6055","authenticated-orcid":true,"given":"Xian","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1111\/pcmr.12684","volume":"31","author":"Passeron","year":"2018","journal-title":"Pigm Cell Melanoma Res"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1111\/exd.13844","volume":"28","author":"Kwon","year":"2019","journal-title":"Exp Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jaad.2023.07.1045","volume":"90","author":"Desai","year":"2024","journal-title":"J Am Acad Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1590\/abd1806-4841.20143063","volume":"89","author":"Handel","year":"2014","journal-title":"An Bras Dermatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12465","volume":"30","author":"Taraz","year":"2017","journal-title":"Dermatol Ther"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.ijpharm.2011.10.042","volume":"422","author":"Yamamoto","year":"2012","journal-title":"Int J Pharm"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1002\/pst.2215","volume":"21","author":"Flight","year":"2022","journal-title":"Pharm Stat"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2459","DOI":"10.1177\/09622802211037073","volume":"30","author":"Lewis","year":"2021","journal-title":"Stat Methods Med Res"},{"key":"ref9","first-page":"110","volume":"54","author":"He","year":"2021","journal-title":"Chin Jl of Dermatology"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/95056","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/95056","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T02:10:17Z","timestamp":1724119817000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/treatment-of-melasma-with-tranexamic-acid-essence-combined-with-iontop-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":9,"URL":"https:\/\/doi.org\/10.2147\/dddt.s472922","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8]]}}}