{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T07:01:38Z","timestamp":1747206098215,"version":"3.40.5"},"reference-count":44,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s474470","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T05:10:12Z","timestamp":1731042612000},"page":"5073-5086","source":"Crossref","is-referenced-by-count":0,"title":["Population Pharmacokinetic\/Pharmacodynamic Study of Linezolid in Hospital-Acquired Pneumonia Patients with Renal Insufficiency"],"prefix":"10.2147","volume":"Volume 18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1580-5625","authenticated-orcid":true,"given":"Jin-hui","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-long","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiwei","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun-long","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu-fen","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenqi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing-Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-xia","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2024,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1056\/NEJMoa1801550","volume":"379","author":"Magill","year":"2018","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00582-2017","volume":"50","author":"Torres","year":"2017","journal-title":"Eur Respir J"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1590\/s1413-86702009000200004","volume":"13","author":"Gales","year":"2009","journal-title":"Braz J Infect Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"3453","DOI":"10.1093\/jac\/dkz371","volume":"74","author":"Antonelli","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1093\/cid\/ciw353","volume":"63","author":"Kalil","year":"2016","journal-title":"Clin Infect Dis"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/1469-0691.12450","volume":"20","author":"Chastre","year":"2014","journal-title":"Clin Microbiol Infect"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1016\/j.jiph.2016.11.016","volume":"10","author":"Djordjevic","year":"2017","journal-title":"J Infect Public Health"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1093\/jac\/dkz520","volume":"75","author":"Arnaud","year":"2020","journal-title":"J Antimicrob Chemother"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.ekir.2020.10.034","volume":"6","author":"Sakhi","year":"2021","journal-title":"Kidney Int Rep"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2259","DOI":"10.2147\/DDDT.S413662","volume":"17","author":"Wang","year":"2023","journal-title":"Drug Des Devel Ther"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1093\/jac\/dkh048","volume":"53","author":"Cepeda","year":"2004","journal-title":"J Antimicrob Chemother"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1093\/jac\/dkh088","volume":"53","author":"Wilcox","year":"2004","journal-title":"J Antimicrob Chemother"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"967311","DOI":"10.3389\/fpubh.2022.967311","volume":"10","author":"Lin","year":"2022","journal-title":"Front Public Health"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1093\/jac\/dkab499","volume":"77","author":"Hanai","year":"2022","journal-title":"J Antimicrob Chemother"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"167","DOI":"10.2165\/00003088-200039030-00001","volume":"39","author":"Wilson","year":"2000","journal-title":"Clin Pharmacokinet"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.ijantimicag.2012.05.025","volume":"40","author":"Yamada","year":"2012","journal-title":"Int J Antimicrob Agents"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.2165\/00003088-200342130-00004","volume":"42","author":"Stalker","year":"2003","journal-title":"Clin Pharmacokinet"},{"key":"ref18","unstructured":"FDA. Highlights of prescribing information for ZYVOX. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/206473s002lbl.pdf. Accessed October 25, 2023."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1080\/14656566.2016.1182154","volume":"17","author":"Morata","year":"2016","journal-title":"Expert Opin Pharmacother"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"106881","DOI":"10.1016\/j.ijantimicag.2023.106881","volume":"62","author":"Shi","year":"2023","journal-title":"Int J Antimicrob Agents"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e00605","DOI":"10.1128\/AAC.00605-19","volume":"63","author":"Crass","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s10096-019-03754-1","volume":"39","author":"Cazavet","year":"2020","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.844567","volume":"13","author":"Wu","year":"2022","journal-title":"Front Pharmacol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1002\/jcph.133","volume":"53","author":"Tsuji","year":"2013","journal-title":"J Clin Pharmacol"},{"key":"ref25","unstructured":"U.S. Department of Health and Human Services. 2010. Guidance for industry pharmacokinetics in patients with impaired renal function-study design, data analysis, and impact on dosing. Available from: https:\/\/www.fda.gov\/media\/78573\/download. Accessed October 27, 2023."},{"key":"ref26","unstructured":"FDA. Summary of product characteristics, labelling and package leaflet. Available from: https:\/\/www.ema.europa.eu\/en\/documents\/referral\/targocid-article-30-referral-annex-iii_en.pdf. Accessed October 27, 2024."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"3588","DOI":"10.1093\/jac\/dkz374","volume":"74","author":"Cojutti","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"R118","DOI":"10.1186\/cc13914","volume":"18","author":"Peyrani","year":"2014","journal-title":"Crit Care"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.1093\/cid\/ciz181","volume":"69","author":"Kaye","year":"2019","journal-title":"Clin Infect Dis"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1186\/cc11454","volume":"17","author":"Kellum","year":"2013","journal-title":"Crit Care"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1186\/s12879-022-07618-6","volume":"22","author":"Xu","year":"2022","journal-title":"BMC Infect Dis"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1128\/AAC.46.5.1475-1480.2002","volume":"46","author":"Conte","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"2334","DOI":"10.1128\/AAC.01885-13","volume":"58","author":"Boak","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1111\/bcp.13262","volume":"83","author":"Tsuji","year":"2017","journal-title":"Br J Clin Pharmacol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1002\/phar.2719","volume":"42","author":"Sakurai","year":"2022","journal-title":"Pharmacotherapy"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.ijantimicag.2014.05.010","volume":"44","author":"Matsumoto","year":"2014","journal-title":"Int J Antimicrob Agents"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s13613-023-01184-z","volume":"13","author":"Tikiso","year":"2023","journal-title":"Ann Intensive Care"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.ijantimicag.2014.07.001","volume":"44","author":"Luque","year":"2014","journal-title":"Int J Antimicrob Agents"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.ijantimicag.2018.01.021","volume":"51","author":"Ide","year":"2018","journal-title":"Int J Antimicrob Agents"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00133-20","volume":"64","author":"Zhang","year":"2020","journal-title":"Antimicrob Agents Chemother"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1093\/jac\/dky500","volume":"74","author":"Xie","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1016\/j.cmi.2020.04.009","volume":"26","author":"Ehmann","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1177\/0091270009337947","volume":"49","author":"Abe","year":"2009","journal-title":"J Clin Pharmacol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00198-019-05190-5","volume":"31","author":"Goto","year":"2020","journal-title":"Osteoporos Int"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/97110","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/97110","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T05:10:16Z","timestamp":1731042616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/population-pharmacokineticpharmacodynamic-study-of-linezolid-in-hospit-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":44,"URL":"https:\/\/doi.org\/10.2147\/dddt.s474470","relation":{},"ISSN":["1177-8881"],"issn-type":[{"type":"electronic","value":"1177-8881"}],"subject":[],"published":{"date-parts":[[2024,11]]}}}