{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T17:11:14Z","timestamp":1785777074497,"version":"3.56.0"},"reference-count":24,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s495604","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T10:55:14Z","timestamp":1750071314000},"page":"5099-5109","source":"Crossref","is-referenced-by-count":3,"title":["Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Yueting","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuo-Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Feng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2858-9668","authenticated-orcid":true,"given":"Jing-Xiang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"3487","DOI":"10.2147\/dddt.S474854","volume":"18","author":"Zhang","year":"2024","journal-title":"Drug Des Devel Ther"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.23736\/s0375-9393.24.18041-8","volume":"90","author":"Wegner","year":"2024","journal-title":"Minerva Anestesiol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s12871-023-01974-9","volume":"23","author":"Sekiguchi","year":"2023","journal-title":"BMC Anesthesiol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"10595","DOI":"10.12998\/wjcc.v9.i34.10595","volume":"9","author":"Tang","year":"2021","journal-title":"World J Clin Cases"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"110955","DOI":"10.1016\/j.jclinane.2022.110955","volume":"82","author":"Choi","year":"2022","journal-title":"J Clin Anesth"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"e00851","DOI":"10.1002\/prp2.851","volume":"9","author":"Liu","year":"2021","journal-title":"Pharmacol Res Perspect"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"111580","DOI":"10.1016\/j.jclinane.2024.111580","volume":"98","author":"Ju","year":"2024","journal-title":"J Clin Anesth"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.2147\/dddt.S186759","volume":"13","author":"Freyer","year":"2019","journal-title":"Drug Des Devel Ther"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1128030","DOI":"10.3389\/fmed.2023.1128030","volume":"10","author":"Xin","year":"2023","journal-title":"Front Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.1016\/s0140-6736(04)16300-9","volume":"363","author":"Myles","year":"2004","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"6605","DOI":"10.3390\/s130506605","volume":"13","author":"Al-Kadi","year":"2013","journal-title":"Sensors"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"10896","DOI":"10.3390\/s101210896","volume":"10","author":"Musizza","year":"2010","journal-title":"Sensors"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1097\/00000542-200012000-00049","volume":"93","author":"Vuyk","year":"2000","journal-title":"Anesthesiology"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1097\/00000542-200003000-00017","volume":"92","author":"Sch\u00fcttler","year":"2000","journal-title":"Anesthesiology"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jchromb.2014.11.022","volume":"976\u2013977","author":"Zhou","year":"2015","journal-title":"J Chromatogr B"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/bf01117450","volume":"6","author":"Yamaoka","year":"1978","journal-title":"J Pharmacokinet Biopharm"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1037\/a0027127","volume":"17","author":"Vrieze","year":"2012","journal-title":"Psychol Methods"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1023\/b:jopa.0000012998.04442.1f","volume":"30","author":"Zhang","year":"2003","journal-title":"J Pharmacokinet Pharmacodyn"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1023\/b:jopa.0000012999.36063.4e","volume":"30","author":"Zhang","year":"2003","journal-title":"J Pharmacokinet Pharmacodyn"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s00228-019-02800-3","volume":"76","author":"Sheng","year":"2020","journal-title":"Eur J Clin Pharmacol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1111\/cts.12875","volume":"14","author":"Zhou","year":"2021","journal-title":"Clin Transl Sci"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"109899","DOI":"10.1016\/j.jclinane.2020.109899","volume":"66","author":"Zhou","year":"2020","journal-title":"J Clin Anesth"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1213\/ANE.0b013e318241f68a","volume":"115","author":"Wiltshire","year":"2012","journal-title":"Anesth Analg"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1097\/aln.0000000000003103","volume":"132","author":"Sch\u00fcttler","year":"2020","journal-title":"Anesthesiology"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/103924","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/103924","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T10:55:14Z","timestamp":1750071314000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/model-informed-precision-dosing-of-remimazolam-in-general-anesthesia-p-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":24,"URL":"https:\/\/doi.org\/10.2147\/dddt.s495604","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}