{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:04:44Z","timestamp":1767906284681,"version":"3.49.0"},"reference-count":51,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s503757","type":"journal-article","created":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T11:10:12Z","timestamp":1741605012000},"page":"1681-1701","source":"Crossref","is-referenced-by-count":1,"title":["Exploring Mechanisms of Lang Qing Ata in Non-Alcoholic Steatohepatitis Based on Metabolomics, Network Pharmacological Analysis, and Experimental Validation"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Shupei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanlong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haifeng","family":"Lan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingzuo","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/hep.29367","volume":"67","author":"Chalasani","year":"2018","journal-title":"Hepatology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"154241","DOI":"10.1016\/j.phymed.2022.154241","volume":"104","author":"Deng","year":"2022","journal-title":"Phytomedicine"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"155789","DOI":"10.1016\/j.metabol.2024.155789","volume":"152","author":"Han","year":"2024","journal-title":"Metabolism"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1001\/jama.2020.2298","volume":"323","author":"Sheka","year":"2020","journal-title":"JAMA"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1053\/j.gastro.2010.09.038","volume":"140","author":"Williams","year":"2011","journal-title":"Gastroenterology"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1053\/j.gastro.2011.06.061","volume":"141","author":"Charlton","year":"2011","journal-title":"Gastroenterology"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"7440","DOI":"10.1038\/s41598-020-64293-w","volume":"10","author":"Majeed","year":"2020","journal-title":"Sci Rep"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1053\/j.gastro.2015.04.043","volume":"149","author":"Angulo","year":"2015","journal-title":"Gastroenterology"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1002\/hep.27368","volume":"61","author":"Ekstedt","year":"2015","journal-title":"Hepatology"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"155914","DOI":"10.1016\/j.metabol.2024.155914","volume":"156","author":"Zhu","year":"2024","journal-title":"Metabolism"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.atherosclerosis.2014.01.014","volume":"233","author":"Gerry","year":"2014","journal-title":"Atherosclerosis"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"S81","DOI":"10.1016\/S0092-8674(02)00703-1","volume":"109","author":"Ghosh","year":"2002","journal-title":"Cell"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"101349","DOI":"10.1016\/j.molmet.2021.101349","volume":"54","author":"Heida","year":"2021","journal-title":"mol Metab"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.1016\/j.bbadis.2013.09.014","volume":"1832","author":"Bartuzi","year":"2013","journal-title":"Biochim Biophys Acta"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"155832","DOI":"10.1016\/j.metabol.2024.155832","volume":"155","author":"Xu","year":"2024","journal-title":"Metabolism"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"149","DOI":"10.5009\/gnl.2012.6.2.149","volume":"6","author":"Farrell","year":"2012","journal-title":"Gut Liver"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3390\/nu14010042","volume":"14","author":"Aoyama","year":"2021","journal-title":"Nutrients"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1159\/000484908","volume":"44","author":"Xuan","year":"2017","journal-title":"Cell Physiol Biochem"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"104447","DOI":"10.1016\/j.yexmp.2020.104447","volume":"115","author":"Xuan","year":"2020","journal-title":"Exp Mol Pathol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/nrm.2016.25","volume":"17","author":"Johnson","year":"2016","journal-title":"Nat Rev mol Cell Biol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"114969","DOI":"10.1016\/j.jep.2022.114969","volume":"288","author":"Wu","year":"2022","journal-title":"J Ethnopharmacol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"116306","DOI":"10.1016\/j.jep.2023.116306","volume":"309","author":"Zhao","year":"2023","journal-title":"J Ethnopharmacol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"117981","DOI":"10.1016\/j.jep.2024.117981","volume":"326","author":"Zhao","year":"2024","journal-title":"J Ethnopharmacol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"37390","DOI":"10.1038\/srep37390","volume":"6","author":"Vasilev","year":"2016","journal-title":"Sci Rep"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"122512","DOI":"10.1016\/j.jchromb.2020.122512","volume":"1164","author":"Demurtas","year":"2021","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1021\/ac8019366","volume":"81","author":"Zelena","year":"2009","journal-title":"Anal Chem"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/nprot.2012.135","volume":"8","author":"Want","year":"2013","journal-title":"Nat Protoc"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"111820","DOI":"10.1016\/j.diabres.2024.111820","volume":"217","author":"Colosimo","year":"2024","journal-title":"Diabetes Res Clin Pract"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1007\/s00204-019-02440-7","volume":"93","author":"Wang","year":"2019","journal-title":"Arch Toxicol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1016\/S0140-6736(20)32511-3","volume":"397","author":"Powell","year":"2021","journal-title":"Lancet"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24065843","volume":"24","author":"Wang","year":"2023","journal-title":"Int J mol Sci"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1106875","DOI":"10.3389\/fendo.2022.1106875","volume":"13","author":"Lv","year":"2022","journal-title":"Front Endocrinol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.biopha.2018.06.134","volume":"108","author":"Liu","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.3389\/fphar.2018.01459","volume":"9","author":"Zhang","year":"2018","journal-title":"Front Pharmacol"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"110286","DOI":"10.1016\/j.biopha.2020.110286","volume":"128","author":"Chen","year":"2020","journal-title":"Biomed Pharmacother"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1002\/hep.31749","volume":"74","author":"Lan","year":"2021","journal-title":"Hepatology"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"2536","DOI":"10.3390\/nu11102536","volume":"11","author":"Mun","year":"2019","journal-title":"Nutrients"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"117828","DOI":"10.1016\/j.jep.2024.117828","volume":"325","author":"Zhang","year":"2024","journal-title":"J Ethnopharmacol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.jhep.2017.10.031","volume":"68","author":"Santhekadur","year":"2018","journal-title":"J Hepatol"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.3748\/wjg.v18.i19.2300","volume":"18","author":"Takahashi","year":"2012","journal-title":"World J Gastroenterol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.jhep.2018.08.026","volume":"70","author":"Zhang","year":"2019","journal-title":"J Hepatol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"5105","DOI":"10.3748\/wjg.v25.i34.5105","volume":"25","author":"Yang","year":"2019","journal-title":"World J Gastroenterol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"917","DOI":"10.3892\/etm.2018.6256","volume":"16","author":"Tsai","year":"2018","journal-title":"Exp Ther Med"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"155658","DOI":"10.1016\/j.phymed.2024.155658","volume":"132","author":"Qiu","year":"2024","journal-title":"Phytomedicine"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.2147\/JIR.S343236","volume":"15","author":"Saha","year":"2022","journal-title":"J Inflamm Res"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"605064","DOI":"10.3389\/fphar.2020.605064","volume":"11","author":"Liu","year":"2020","journal-title":"Front Pharmacol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.7150\/ijbs.26086","volume":"14","author":"Li","year":"2018","journal-title":"Int J Biol Sci"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1002\/hep.30215","volume":"69","author":"Wang","year":"2019","journal-title":"Hepatology"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1038\/nrgastro.2013.149","volume":"10","author":"Wree","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1016\/j.jhep.2017.01.022","volume":"66","author":"Mridha","year":"2017","journal-title":"J Hepatol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"400","DOI":"10.21037\/atm.2020.02.184","volume":"8","author":"M\u00e9ndez-S\u00e1nchez","year":"2020","journal-title":"Ann Transl Med"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/100959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/100959","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T11:10:15Z","timestamp":1741605015000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/exploring-mechanisms-of-lang-qing-ata-in-non-alcoholic-steatohepatitis-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":51,"URL":"https:\/\/doi.org\/10.2147\/dddt.s503757","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3]]}}}