{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T11:31:41Z","timestamp":1769513501678,"version":"3.49.0"},"reference-count":62,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s519597","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T13:45:12Z","timestamp":1751550312000},"page":"5709-5725","source":"Crossref","is-referenced-by-count":3,"title":["Significant Predictors of Azithromycin in Population Pharmacokinetic Analysis: A Systematic Review"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Runcong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuebin","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinhui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiming","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weibin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuetian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2222-8228","authenticated-orcid":true,"given":"Bin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.pharmthera.2014.03.003","volume":"143","author":"Parnham","year":"2014","journal-title":"Pharmacol Ther"},{"key":"ref2","unstructured":"ZITHROMAX\u00ae. (Azithromycin) Tablets [Prescribing Information]. Groton: Pfizer, Inc; 2021."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.imj.2021.11.001","volume":"1","author":"Abdallah","year":"2022","journal-title":"Infectious Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"3g5237","DOI":"10.1136\/bmj.g5237","volume":"49","author":"Aaron","journal-title":"BMJ"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1056\/NEJMoa1104623","volume":"365","author":"Albert","year":"2011","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1016\/j.rmed.2013.05.004","volume":"107","author":"Donath","year":"2013","journal-title":"Respir Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/j.chest.2017.04.167","volume":"152","author":"Henkle","year":"2017","journal-title":"Chest"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60953-2","volume":"380","author":"Wong","year":"9842","journal-title":"Lancet"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e1002835","DOI":"10.1371\/journal.pmed.1002835","volume":"16","author":"Arzika","year":"2019","journal-title":"PLoS Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1038\/s41467-022-28565-5","volume":"13","author":"Arzika","year":"2022","journal-title":"Nat Commun"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.1056\/NEJMoa1811400","volume":"380","author":"Chandramohan","year":"2019","journal-title":"N Engl J Med"},{"key":"ref12","unstructured":"WHO Database [homepage on the Internet]. Global Antimicrobial Resistance and Use Surveillance System (GLASS) report antibiotic use data for 2022; 2025. Available from: https:\/\/www.who.int\/pubLications\/i\/item\/9789240062702. Accessed May 14, 2025."},{"key":"ref13","unstructured":"Centers for Disease Control and Prevention Database [homepage on the Internet]. Outpatient antibiotic prescriptions \u2014 United States, 2022; 2025. Available from: https:\/\/archive.cdc.gov\/#\/details?url=https:\/\/www.cdc.gov\/antibiotic-use\/data\/report-2022.html. Accessed May 14, 2025."},{"key":"ref14","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/s002849900290","volume":"36","author":"Champney","year":"1998","journal-title":"Curr Microbiol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1007\/s002849900402","volume":"37","author":"Champney","year":"1998","journal-title":"Curr Microbiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/s1097-2765(02)00570-1","volume":"10","author":"Hansen","year":"2002","journal-title":"Mol Cell"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"3485","DOI":"10.1128\/aac.00527-07","volume":"51","author":"Dahl","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/s0009-9236(97)90098-9","volume":"61","author":"Luke","year":"1997","journal-title":"Clin Pharmacol Ther"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1007\/bf01975839","volume":"10","author":"Coates","year":"1991","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref20","first-page":"505","volume":"43","author":"Singlas","year":"1995","journal-title":"Pathol Biol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/jac\/37.suppl_c.1","volume":"37","author":"Lode","year":"1996","journal-title":"J Antimicrob Chemother"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1093\/jac\/dky548","volume":"74","author":"Kong","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1177\/0091270010382021","volume":"51","author":"Hassan","year":"2011","journal-title":"J Clin Pharmacol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1097\/01.inf.0000148927.48680.fc","volume":"24","author":"Jacobs","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1128\/aac.00771-09","volume":"54","author":"Salman","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1093\/cid\/cit137","volume":"56","author":"Coles","year":"2013","journal-title":"Clin Infect Dis"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/0010-4809(72)90051-1","volume":"5","author":"Sheiner","year":"1972","journal-title":"Comput Biomed Res"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.2217\/pgs.09.65","volume":"10","author":"Sasaki","year":"2009","journal-title":"Pharmacogenomics"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"n71","DOI":"10.1136\/bmj.n71","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s40262-013-0114-1","volume":"53","author":"Jamsen","year":"2014","journal-title":"Clin Pharmacokinet"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1007\/s40262-015-0236-8","volume":"54","author":"Kanji","year":"2015","journal-title":"Clin Pharmacokinet"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/bcp.12233","volume":"79","author":"Duffull","year":"2015","journal-title":"Br J Clin Pharmacol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1080\/17512433.2023.2219055","volume":"16","author":"Mao","year":"2023","journal-title":"Expert Rev Clin Pharmacol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1038\/ki.2009.504","author":"Christians","year":"2010","journal-title":"Kidney Int Suppl"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700","volume":"62","author":"Liberati","year":"2009","journal-title":"Journal of clinical epidemiology"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"662","DOI":"10.5414\/cpp48662","volume":"48","author":"Zhang","year":"2010","journal-title":"Int J Clin Pharmacol Ther"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1093\/jac\/dkq398","volume":"66","author":"Muto","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"e103","DOI":"10.1038\/psp.2013.80","volume":"3","author":"Sampson","year":"2014","journal-title":"CPT Pharmacometrics Syst Pharmacol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/1475-2875-13-36","volume":"13","author":"Zhao","year":"2014","journal-title":"Malar J"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"6675","DOI":"10.1128\/aac.02904-14","volume":"58","author":"Zheng","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s13318-018-0522-6","volume":"44","author":"Wu","year":"2019","journal-title":"Eur J Drug Metab Pharmacokinet"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1002\/cpt.2665","volume":"112","author":"Chotsiri","year":"2022","journal-title":"Clin Pharmacol Ther"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1128\/aac.00717-11","volume":"56","author":"Fischer","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2127","DOI":"10.1128\/aac.02183-12","volume":"57","author":"Viscardi","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1128\/aac.03951-14","volume":"59","author":"Merchan","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00686-18","volume":"62","author":"Zheng","year":"2018","journal-title":"Antimicrob Agents Chemother"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1016\/j.xphs.2024.01.012","volume":"113","author":"Zhang","year":"2024","journal-title":"J Pharm Sci"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"3194","DOI":"10.1128\/aac.02430-12","volume":"57","author":"Pene Dumitrescu","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1080\/17512433.2023.2196401","volume":"16","author":"Li","year":"2023","journal-title":"Expert Rev Clin Pharmacol"},{"key":"ref50","volume-title":"Copyright \u00a9 2025","year":"2025"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1128\/aac.39.8.1875","volume":"39","author":"Nahata","year":"1995","journal-title":"Antimicrob Agents Chemother"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1080\/10408398.2011.640757","volume":"54","author":"Bourlieu","year":"2014","journal-title":"Crit Rev Food Sci Nutr"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.ejps.2018.07.022","volume":"123","author":"Van Den Abeele","year":"2018","journal-title":"Eur J Pharm Sci"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1515\/cclm-2014-1273","volume":"53","author":"Jahnel","year":"2015","journal-title":"Clin Chem Lab Med"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.4269\/ajtmh.2007.76.1153","volume":"76","author":"Amsden","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/s0029-7844(99)00533-5","volume":"95","author":"Leslie","year":"2000","journal-title":"Obstet Gynecol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1128\/aac.48.3.809-814.2004","volume":"48","author":"Sugie","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"151221","DOI":"10.1016\/j.semperi.2020.151221","volume":"44","author":"Pinheiro","year":"2020","journal-title":"Semin Perinatol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1007\/s00228-003-0651-x","volume":"59","author":"McGready","year":"2003","journal-title":"Eur J Clin Pharmacol"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.seizure.2007.11.017","volume":"17","author":"Ohman","year":"2008","journal-title":"Seizure"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/s0149-2918(96)80179-2","volume":"18","author":"Amsden","year":"1996","journal-title":"Clin Ther"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jac\/dki241","volume":"56","author":"Girard","year":"2005","journal-title":"J Antimicrob Chemother"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/104478","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/104478","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T13:45:14Z","timestamp":1751550314000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/significant-predictors-of-azithromycin-in-population-pharmacokinetic-a-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":62,"URL":"https:\/\/doi.org\/10.2147\/dddt.s519597","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]}}}