{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:53:20Z","timestamp":1790596400958,"version":"4.1.0"},"reference-count":51,"publisher":"Informa UK Limited","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DDDT"],"DOI":"10.2147\/dddt.s523836","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T09:25:14Z","timestamp":1750238714000},"page":"5209-5230","source":"Crossref","is-referenced-by-count":10,"title":["Multi-Target Mechanism of Compound Qingdai Capsule for Treatment of Psoriasis: Multi-Omics Analysis and Experimental Verification"],"prefix":"10.2147","volume":"Volume 19","author":[{"given":"Yuanyuan","family":"Qiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2897-5208","authenticated-orcid":true,"given":"Canzhe","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chupeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peilin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxiang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7313-1859","authenticated-orcid":true,"given":"Na","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangyong","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1001\/jamadermatol.2023.4990","volume":"160","author":"Eichenfield","year":"2024","journal-title":"JAMA dermatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.2174\/1389450122666210118103455","volume":"22","author":"Singh","year":"2021","journal-title":"Current Drug Targets"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"115078","DOI":"10.1016\/j.psychres.2023.115078","volume":"321","author":"Liu","year":"2023","journal-title":"Psychiatry Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/s12964-023-01381-0","volume":"22","author":"Liu","year":"2024","journal-title":"Cell commun signal"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"941071","DOI":"10.3389\/fimmu.2022.941071","volume":"13","author":"Kamata","year":"2022","journal-title":"Front Immunol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"11574","DOI":"10.3390\/ijms222111574","volume":"22","author":"Vi\u010di\u0107","year":"2021","journal-title":"Int J Mol Sci"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"13313","DOI":"10.3390\/ijms241713313","volume":"24","author":"Lee","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref9","first-page":"261","volume":"35","author":"Zheng","year":"2021","journal-title":"Chin J Dermatovenereol"},{"key":"ref10","first-page":"2776","volume":"17","author":"Shi","year":"2022","journal-title":"World Chin Med"},{"key":"ref11","unstructured":"Committee on Psoriasis CSoD. Guideline for the diagnosis and treatment of psoriasis in China (2023 edition). Chin Jl of Dermatol. 2023;56(7):573\u2013625."},{"key":"ref12","first-page":"871","volume":"22","author":"Yang","year":"2022","journal-title":"Eval Anal Drug-Use Hospitals China"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e976","DOI":"10.1002\/ctm2.976","volume":"12","author":"Deng","year":"2022","journal-title":"Clin transl med"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"155231","DOI":"10.1016\/j.phymed.2023.155231","volume":"123","author":"Lv","year":"2024","journal-title":"Phytomedicine"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/s42256-021-00325-y","volume":"3","author":"Schulte-Sasse","year":"2021","journal-title":"Nature Mach Intell"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"i501","DOI":"10.1093\/bioinformatics\/btz318","volume":"35","author":"Sharifi-Noghabi","year":"2019","journal-title":"Bioinformatics"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"240","DOI":"10.3390\/genes10030240","volume":"10","author":"Xie","year":"2019","journal-title":"Genes"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1142\/S0192415X22500045","volume":"50","author":"Chen","year":"2022","journal-title":"Am J Chin Med"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1111\/exd.14497","volume":"31","author":"Solvin","year":"2022","journal-title":"Exp dermatol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.jdermsci.2023.01.003","volume":"109","author":"Blauvelt","year":"2023","journal-title":"J Dermatological Sci"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"W726","DOI":"10.1093\/nar\/gkac297","volume":"50","author":"Gallo","year":"2022","journal-title":"Nucleic Acids Res"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1038\/s41698-025-00825-9","volume":"9","author":"Henke","year":"2025","journal-title":"NPJ Precision Oncol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.ijrobp.2023.08.042","volume":"118","author":"Salazar","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3390\/biom13050723","volume":"13","author":"Dong","year":"2023","journal-title":"Biomolecules"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"D368","DOI":"10.1093\/nar\/gkad1011","volume":"52","author":"Varadi","year":"2024","journal-title":"Nucleic Acids Res"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.jaci.2020.04.034","volume":"147","author":"Sch\u00f6n","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1007\/s10787-023-01198-w","volume":"31","author":"Shahine","year":"2023","journal-title":"Inflammopharmacology"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"116935","DOI":"10.1016\/j.jep.2023.116935","volume":"318","author":"Xie","year":"2024","journal-title":"J Ethnopharmacol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1016\/j.jid.2019.01.006","volume":"139","author":"Moos","year":"2019","journal-title":"J invest dermatol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"3000605221117138","DOI":"10.1177\/03000605221117138","volume":"50","author":"Li","year":"2022","journal-title":"J Int Med Res"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"4526","DOI":"10.1002\/ptr.7155","volume":"35","author":"Zhang","year":"2021","journal-title":"Phytother Res"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"279","DOI":"10.5021\/ad.2019.31.3.279","volume":"31","author":"Zhang","year":"2019","journal-title":"Annals dermatol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"40228","DOI":"10.1021\/acsami.3c07582","volume":"15","author":"Zhang","year":"2023","journal-title":"ACS Appl Mater Interfaces"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1089\/ars.2019.7835","volume":"35","author":"Tsai","year":"2021","journal-title":"Antioxid Redox Signaling"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"11146","DOI":"10.1080\/21655979.2022.2062090","volume":"13","author":"Tao","year":"2022","journal-title":"Bioengineered"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/exd.13511","volume":"27","author":"Tang","year":"2018","journal-title":"Exp dermatol"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"113331","DOI":"10.1016\/j.jpba.2020.113331","volume":"186","author":"Chen","year":"2020","journal-title":"J Pharmaceut Biomed Anal"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1016\/j.jid.2022.02.018","volume":"142","author":"Huang","year":"2022","journal-title":"J invest dermatol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"3867","DOI":"10.3390\/cells11233867","volume":"11","author":"Dorai","year":"2022","journal-title":"Cells"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1208\/s12249-023-02678-6","volume":"24","author":"Dadwal","year":"2023","journal-title":"AAPS Pharm Sci Tech"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"598","DOI":"10.4103\/ijd.ijd_10_21","volume":"66","author":"Wang","year":"2021","journal-title":"Indian j dermatol"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1038\/s41416-024-02584-z","volume":"130","author":"Shah","year":"2024","journal-title":"Br J Cancer"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"4631","DOI":"10.18632\/aging.205618","volume":"16","author":"Li","year":"2024","journal-title":"Aging"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1007\/s10616-021-00496-x","volume":"73","author":"Fang","year":"2021","journal-title":"Cytotechnology"},{"key":"ref45","first-page":"1","volume":"2024","author":"Chen","year":"2024","journal-title":"J Adv Res"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"6618924","DOI":"10.1155\/2021\/6618924","volume":"2021","author":"Kumar","year":"2021","journal-title":"Mediators Inflammation"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"e557","DOI":"10.1111\/jdv.19701","volume":"38","author":"Bachelez","year":"2024","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1002\/ptr.8405","volume":"39","author":"Gupta","year":"2025","journal-title":"Phytother Res"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"118166","DOI":"10.1016\/j.jep.2024.118166","volume":"330","author":"Wang","year":"2024","journal-title":"J Ethnopharmacol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"155381","DOI":"10.1016\/j.phymed.2024.155381","volume":"128","author":"Wang","year":"2024","journal-title":"Phytomedicine"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.3390\/nu16162690","volume":"16","author":"Jo","year":"2024","journal-title":"Nutrients"}],"container-title":["Drug Design, Development and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.dovepress.com\/article\/download\/104015","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.dovepress.com\/article\/download\/104015","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T09:25:20Z","timestamp":1750238720000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dovepress.com\/multi-target-mechanism-of-compound-qingdai-capsule-for-treatment-of-ps-peer-reviewed-fulltext-article-DDDT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":51,"URL":"https:\/\/doi.org\/10.2147\/dddt.s523836","relation":{},"ISSN":["1177-8881"],"issn-type":[{"value":"1177-8881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]}}}